[quote]wannabebig250 wrote:
i wish i could get my hands on some arimidex 
[/quote]
Research chems distributors or out of country pharmacies would be your best bet.
[quote]MAF14 wrote:
[quote]wannabebig250 wrote:
i wish i could get my hands on some arimidex
[/quote]
Research chems distributors or out of country pharmacies would be your best bet.[/quote]
yea but ive read too many posts about bunk liquidex from these research chem sites.
Hmm just curious in regards to Waylanderxx post. Does anyone know if a combination DAA + Trimethylglycinwould would elevate the T levels in someone who has normal or slightly above normal levels? Anyone have experience with this? I recently stopped all supplement use with the exception of whey protein because I came to the conclusion it was all bullshit.
[quote]paulieserafini wrote:
[quote]wannabebig250 wrote:
4 in the morning, 3 at night. 5 days on 2 off, bottle lasts a month. i have yet to try it im kind scared its pretty powerful hahah[/quote]
lol my fear would be they didn’t put the amount requested for all the stuff[/quote]
lol well i just popped 2 when i wokeup and will pop 2 more before my workout today so we’ll see if its dosed properly.
i got
zinc gluconate 30mg
zinc monomethionine 30mg with vitamin b-6 pyridoxine hcl 20mg
magnesium citrate 400mg
grape seed (standardized 95% (47.5mg) proanthocyanidins) 50mg
and also
grape seed extract 95% polyphenols 100mg, with vitamin c (as ascorbic acid) 200mg
are any of these better than the other?
anyone know the dosing for grape seed extract?
i figured id have like 200mg 2x a day?
[quote]paulieserafini wrote:
i got
zinc gluconate 30mg
magnesium citrate 400mg
grape seed (standardized 95% (47.5mg) proanthocyanidins) 50mg
are any of these better than the other?
anyone know the dosing for grape seed extract?
i figured id have like 200mg 2x a day?[/quote]
grape seed extract 200mg 2x a day is correct. you want the 50mg as it is standardized to proanthocyanidins, while the other one is just listed as polyphenols. the proanthocyanidins are what work their anti aromatase magic.
zinc gluconate is good enough you dont really need the other one.
okay sweet thanks.
i was trying to find dosing protocols for the grape seed extract. some say 50-300mg a day
others say 300mg a day for 3 weeks and then a maintinenance of 50-100mg a day
can you link me to your source that says 400mg a day indefinitely?
edit. holy shit that stuff is 16$ dollars a bottle and it looks as if there is only enough for a weeks worth if that damn!
edit again, found a cheaper source that also says proanthocyanidins on the label
[quote]paulieserafini wrote:
okay sweet thanks.
i was trying to find dosing protocols for the grape seed extract. some say 50-300mg a day
others say 300mg a day for 3 weeks and then a maintinenance of 50-100mg a day
can you link me to your source that says 400mg a day indefinitely?
edit. holy shit that stuff is 16$ dollars a bottle and it looks as if there is only enough for a weeks worth if that damn![/quote]
im just going by what patrick arnold says. he knows his shit. im still interpreting some medical studies trying to find out the dosages in them.
ive seen as high as 1000mg, there is no toxicity really, its more about what you can afford and the point of diminishing returns.
theres a book called the testosterone syndrome by dr eugene shippen and he prescribes grape seed extract for estrogen but i havent bought the book so im not sure the dose he recommends.
“For grape seed extract, a daily dosage of 200 to 400 mg is used to treat edema and 150 to 300 mg to treat chronic venous insufficiency, notes the University of Maryland Medical Center. You could take 25 to 150 mg of grape seed extract up to three times daily for general antioxidant effects.”
vitshoppe brand this is what i want right?
GRAPE SEED EXTRACT (MEGANATURAL GOLD) (VITIS VINIFERA)(SEED) STD. TO 90% PROANTHOCYANIDINS 90MG
100 Mg
http://www.denvernaturopathic.com/news/dietaryaromataseinhibitors.html
The current Phase I trial of grape seed extract is attempting to measure whether it prevents cancer in women with risk factors for developing breast cancer. Doses being tested range from 50 mg to 300 mg per day.
We have also examined the effect of GSE on aromatase expression. Reverse transcription-PCR experiments showed that treatment with 60 mug/mL of GSE suppressed the levels of exon I.3-, exon PII-, and exon I.6-containing aromatase mRNAs in MCF-7 and SK-BR-3 cells.
[quote]paulieserafini wrote:
vitshoppe brand this is what i want right?
GRAPE SEED EXTRACT (MEGANATURAL GOLD) (VITIS VINIFERA)(SEED) STD. TO 90% PROANTHOCYANIDINS 90MG
100 Mg
[/quote]
yea thats a good one. 3-4 pills a day and youre good.
Some natural supplements may assist in reducing the symptoms of estrogen dominance, including a daily dose of up to 1,000 mg of grape seed extract, up to 4 grams of taurine or a daily capsule of fish oil (derived from deep-water fish).
Grape Seed Extract Inhibits Lipases without the, uh, Bottom Effects
For those whose dietary and exercise habits are less than perfect and who would like to battle the bulge without setting up shop in the bathroom, there is a promising alternative: grape seed extract. Its abundance of polyphenolic compounds is believed to be largely responsible for its health benefits, which include an antiobesity effect and an enhancement of insulin sensitivity (which is the opposite of insulin resistance). Most notable among these compounds are anthocyanins and proanthocyanidins, which are two types of flavonoids. Also present are nonflavonoid polyphenols, such as the longevity-inducing compound resveratrol (see ?Revolutionary Antiaging Discovery with Resveratrol? in the January 2007 issue).
Like orlistat, grape seed extract (GSE) inhibits lipases?but not as strongly, so social faux pas are not as likely to occur. Furthermore, and unlike orlistat, GSE is absorbed by the gut and enters the circulation, where it can also exert its effects on lipases found there. In a paper published in 2003, a group of American researchers who were interested in this effect wrote,1
Ingestion of natural antioxidants, such as grape seed extract (GSE) rich in proanthocyanidins, has been demonstrated to improve insulin sensitivity and/or ameliorate free radical formation and reduce the signs and symptoms of chronic age-related disorders, including syndrome X.
(Syndrome X is the metabolic syndrome; see the sidebar.) To gain insight on how GSE accomplishes this, the researchers studied its inhibitory effects on three lipases: pancreatic lipase, which is found in the intestine and is the most important enzyme for digesting dietary fats; lipoprotein lipase, which is found in the blood; and hormone-sensitive lipase, which is found in adipose tissue (fat). All three tend to promote the storage of body fat, but by somewhat different mechanisms.
Grape Seed Extract May Help Prevent Insulin Resistance
The researchers tested GSE?s effects on the first two of these enzymes (from human sources) in test-tube experiments and on the third enzyme in cultured mouse adipocytes (fat cells). Test tubes and mouse fat are far cries from actual human beings, but it?s a start. The results showed that, in a dose-dependent manner, GSE strongly inhibited pancreatic lipase; it also inhibited lipoprotein lipase, less strongly but still significantly.
In the third experiment, the researchers incubated the cultured mouse adipocytes with GSE for 18 hours and then used a chemical agent to stimulate the breakdown of triglycerides to produce fatty acids and glycerol. They observed that GSE inhibited the breakdown (again in a dose-dependent manner), presumably by inhibiting hormone-sensitive lipase. This finding implies that human adipocytes might take up GSE from the circulation (in contrast to orlistat, which, as noted above, works only in the intestine and never reaches the circulation in the first place). If this were true, it could potentially reduce the levels of circulating free fatty acids and thus help prevent the development of insulin resistance in obese people.
A Single High Dose Improves Lipid Profile
In related research, Spanish investigators analyzed the acute effects of grape seed proanthocyanidins, the most abundant polyphenols in red wine, on healthy male rats with normal blood lipid levels.2 Each rat received a very high but nontoxic oral dose of an extract consisting almost exclusively of proanthocyanidins. Five hours later, the animals were killed for analysis of their blood lipids and their liver, muscle, and fat tissues. The purpose was to evaluate the rats? ?atherosclerotic risk index? by examining the effects of red wine polyphenols that reportedly protect and enhance the function of both heart and blood vessels.
In the authors? words, the extract ?drastically improved plasma lipidic profile.? Specifically, it lowered triglycerides by 50% and apolipoprotein B (a potentially harmful lipoprotein) by 40%. It also significantly lowered free fatty acids and LDL-cholesterol (?bad cholesterol?) while slightly increasing HDL-cholesterol (?good cholesterol?); oddly, though, total cholesterol levels were unchanged.
The rats? livers showed suppression of some enzymes and enhancement of others, including one whose overexpression implies an increased elimination of cholesterol via the bile. Muscles had more lipoprotein lipase (useful for extracting energy from fats), and fat tissue had less. A key signaling protein was also increased. (The level of each enzyme or protein was inferred from the measured amount of the mRNA molecule that codes for it.)
Anyone heard of nicotine gum reducing estrogen?
MAF
any reason why you took your zinc in the morning instead of at night like most ZMA users do?
okay so for now ive decided to go with:
Rhodiola 300mg in the morning 30 minutes before breakfast
vit D3 6,000 IU with breakfast
1 alaskan fish oil pill with breakfast and another at my 6pm meal
grape seed extract 200mg 8-9am with breakfast and another 200mg with my 3:00pm meal
animal pak multivitamins with my 6-7pm meal
zinc gluconate 30mg and magnesium 400mg at 9:30-10pm just before bed
ill be getting a blood test in 3-4 weeks hopefully this helps i feel like im taking 100 pills a day.
grape seed extract. should i ever cycle this? assuming it works awesome.
[quote]paulieserafini wrote:
MAF
any reason why you took your zinc in the morning instead of at night like most ZMA users do?[/quote]
I didn’t have ZMA at that point, I had separate bottles of Zinc and Magnesium. Aside from that zinc is best taken on empty stomach (so taken in morning) and magnesium is supposed to help with sleep (taken 30 mins per bed).
About your cortisol, supplements may help but you also need to rest and relax. I have adrenal insufficiency - low cortisol - and the only way I started feeling better was from lifting less, eating more, and taking a few supplements that helped… Or most likely a combination of all of them.
[quote]paulieserafini wrote:
okay so for now ive decided to go with:
Rhodiola 300mg in the morning 30 minutes before breakfast
vit D3 6,000 IU with breakfast
1 alaskan fish oil pill with breakfast and another at my 6pm meal
grape seed extract 200mg 8-9am with breakfast and another 200mg with my 3:00pm meal
animal pak multivitamins with my 6-7pm meal
zinc gluconate 30mg and magnesium 400mg at 9:30-10pm just before bed
ill be getting a blood test in 3-4 weeks hopefully this helps i feel like im taking 100 pills a day.
grape seed extract. should i ever cycle this? assuming it works awesome.[/quote]
good plan. if the GSE works for you i see no reason to cycle it. maybe cut back to a maintenance dose of 200mg. its just a really powerful antioxidant, so no cycle is needed.
[quote]wannabebig250 wrote:
Some natural supplements may assist in reducing the symptoms of estrogen dominance, including a daily dose of up to 1,000 mg of grape seed extract, up to 4 grams of taurine or a daily capsule of fish oil (derived from deep-water fish).
[/quote]
Why not just take an anti estrogen. Oh wait, this is supposed to be natural.
[quote]roguevampire wrote:
[quote]wannabebig250 wrote:
Some natural supplements may assist in reducing the symptoms of estrogen dominance, including a daily dose of up to 1,000 mg of grape seed extract, up to 4 grams of taurine or a daily capsule of fish oil (derived from deep-water fish).
[/quote]
Why not just take an anti estrogen. Oh wait, this is supposed to be natural.[/quote]
what would you suggest? ive tried Androst-3,5-dien-7,17-dione already. if GSE doesnt work my last resort is arimidex.