My father has this, as well, and it’s no fun. He will be 50 this year, but has had it for probably 15 years now. His started in the same place as yours, but he also got it across the palm, and small lumps of it near the ball of the thumb.
Take it seriously. His came from freezing his hands a lot, and abusing them on things like rachets and wrenches. It’s caused largely by impact to the hand, but pressure is also problematic. Hopefully you don’t get the overgrowths on the knuckles as well, but I’m not sure if that is a separate issue.
As for lifting, I haven’t given it up, though I have already had the first little lump appear on my own hand (hooray genetics) Start wearing gloves for any lifting that involves the weight sitting on your hand (bench, for example) If you can stand to have them on for all exercises, that would be even better, but I can’t manage DL with them on.
Choose a glove that has some sort of gel inserts to protect your hand (mechanics gloves often have this) and wear them any time you will be lifting/doing manual labour. Don’t fuck around, or your hand will end up curled into a fist permanently (which happened to my grandfather, the mechanic)
A sidenote on surgery: it can be done to remove the build-up, but typically removal of the tissue pads in your hand must happen at the same time, leaving you with no padding over your tendons. Also, if it isn’t completely removed, you may have it grow back bigger as a result of the trauma during the operation. Talk to your doctor about getting some sort of anti-inflammatory for post-surgery, as that may help keep it from coming back.
A sidenote on heredity: Yeah, it’s a little odd that you ended up with it…Typically it travels along specific bloodlines. You’re most likely to get it if:
a)your father/grandfather has it
b)you’re of scottish/irish descent
c)you genetically have large, broad hands
Sex doesn’t seem to matter, as both my aunt and my older sister have shown signs of it.
Be careful, and as gentle as you can with your hands. Best of luck.