Start of Experiment: Estradiol Valerate

If I see a woman using the products on Amazon, it is because it is not working.

You’re looking at foods, soy, fennel, sesame seeds, garlic, flax seeds, red wine, etc.

So you are saying, to use these to increase Estradiol, instead of this cream…

Did you confirm vitamin D dropping your E2 on blood test with no other factor involved. I’ve had bad luck with vitamin d supplements before, just felt funny.

Tested low recently and started using them again. Almost done with whole months worth of capsules and been having brain fog last week or so with dry cracked lip.

Yes. I dropped all of my supplements and vitamins, leveled out, took labs and got an E2 reading. Took 5k vitamin D a day for about 1 week and retested and it dropped my E2 considerably.

Maybe after my levels bounce back from this whole month I can maintain with 5k twice a week.

In my experience, the people I see that used the OTC hormone creams are talking to me (because now they want HRT) because they did not work. I’m not saying they do not work on anyone, some must think they do or they wouldn’t exist. So, I see a biased sample.

No harm trying, if it does not work you simply move on the something else.

I referenced some food off the top of my head known to support estradiol. I’ve known guys that used beer after crashing E2 with an aromatase inhibitor.

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Thank you for your information. Any concern with the other ingredient, as i understand which is estrone? From what i understand, is largely inactive in males.

none

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Inspired by @Robroy I got my doctor to prescribe me estradial pills, I will start with 1mg/day, do labs after four weeks and titrate upwards if necessary.

Similar to rob, I’ve been on TRT for three years now, tried every protocol under the sun to no avail.

Numbers have always come back looking good but I have always suspected that my E2 was too low relative to my Total test. For reference, when I was at 1500 test, my E2 was 40 and at 1100 test, my E2 was 24. I feel like my E2 should be in the 75-100 range at a test of 1100 so that’s what I’ll be shooting for.

I have all the low T symptoms of low mood/libido/strength/endurance/stamina/etc but my main issues are low penile sensitivity and sleep problems which I feel are linked to estrogen imbalance.

I will update the thread if/when I experience something noteworthy, wish me luck!

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I’ve tested with E2 in a ratio of 40:1 when I went higher dose peepee worked so so.

Stopped messing with estrogen for a long while and last tested around 20:1 ratio with E2 being 38 on trough injecting twice a week. Dick was pretty much useless.

Dropped T for a dose or two and went down to 100mg without messing with E2 or anything and it’s working pretty reasonable again.

Not sure what my problem is with higher dosing and losing all function of my dick as I said higher estrogen, lower estrogen, higher ratio, lower ratio, nothing god damn works for me when I inject higher dose even if it’s within TRT parameters of 140-160mg. (Overall though letting my E2 rise that much made things worse, or not better at the very least not sure. For certain higher dosing just kills me)

Good luck Bill!

I’m on 3mg estradiol/day; with TT around 1300, Free-T in the low-mid 20’s, and E2 ~70 I feel better than I have in years. I must not be an aromatizer and my SHBG is also high so whatever estrogen I was producing may have been getting bound up. Even on TRT my E2 (unsupplemented) was in the 20’s and 30’s.

I was also experiencing persistent low penis sensitivity, weak orgasms, and meh libido even on TRT. Since the whole reason I got on TRT was my very high SHBG and resultant low free T, I speculated that my symptoms may be from low estrogen (low free estrogen, especially, given my history with high SHBG) relative to my TT.

A few months after being on estradiol and the low sensitivity, weak orgasm, and libido issues have completely dissipated. I started out on 1mg estradiol/day for 30-60 days, then bumped to 2mg, and finally 3mg to try to push my T:E ratio down to around 20:1.

Oddly, even the somewhat frequent shoulder/back/chest acne flareups I would get since starting TRT have also completely gone away the last few months which may be further circumstantial evidence my T and E are pretty balanced.

Good luck on your journey man! Took me a ton of fiddling and 2.5 years to get dialed in (and a great GP that allowed me to research and expirement, within reason) so don’t get disheartened. If you can find a good balance for you it’s definitely worth the time and energy!

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Thank you for sharing your experience; it is very encouraging!

Men taking estrogen pills are definitely a minority, as I’ve only come across a handful of testimonials on this.

I truly hope this is the missing piece. I have been at it for three years, and I can’t spend the rest of my life in this state of misery.

Hopefully, I will have some good news to report in a few weeks. :crossed_fingers:

Very similar to me with all the symptoms and then improvement but not with higher E2, just simply lowering my T dose. Higher dose with the same “ratio” does shit for me.

Interesting. Crazy how different so many people are WRT what works and what doesn’t.

Hello sir!
Would it be OK if I reached out to you personally through email?
I am in the exact same situation you are and had some questions about exogenous estradiol supplementation
I appreciate it in advance,
Your story is a massive inspiration for guys like me! :+1:t2:

Update 1: Hi Guys, please find below my lab results after four weeks of taking 1mg estradiol tablets. This is not estradiol valerate; it’s just estradiol pills in case that matters.

Total Testosterone: 1380.2 (up from 653)

Free Testosterone: 57.83 (up from 31.41)

Estradiol: 43.5 (up from 20.3)

SHBG: 33.4

In addition to the pills, my TRT protocol is 160mg/ week, injected into my glutes twice a week. This is an increase from the 128mg which I was injecting SubQ twice a week. I also take 200 IU of HCG, injecting it twice a week, but I plan to discontinue this once the vial is empty.

Regarding my response to the pills, the only noticeable change is that I now experience random erections from erotic thoughts or while looking at porn. The most significant difference is that I now produce precum when I’m aroused. For context, I previously needed a significant amount of stimulation to achieve an erection, let alone produce precum. Now, I wake up with a boner and dripping precum which is hopefully a sign of good things to come :crossed_fingers:

That being said, my sexual function is still impaired, and I have yet to see any symptom resolution. I’m therefore increasing the dose to 2mg, will do labs after another four weeks, and report back. I’m aiming for 100pg/mL as that would be a good ratio with my current test levels. I might reduce my testosterone dose as I don’t need my levels that high but just want to focus on estradiol for now and not change multiple variables.

Please let me know if you have any feedback, thanks!

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This is good info. Where did you source the meds if you dont mind me asking. I Have problems crashing my e2 on normal TRT doses with just about every supplement. Sucks.

I am a patient at Marek Health.

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I recently upped my Test dose to achieve TT 1875ng from 1050ng and e2 78pg from 33pg. My libido has never been higher lol. I would usually be using an AI to keep my e2 below 50pg as I thought that was my threshold point, but apparently can go much higher and be fine. I’ve given up on the “low e2 is better for libido” ideas at this point.

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Yeah, there are definitely many misunderstandings about the role of estrogen in the TRT forums. The last clinic I visited didn’t even measure E2 because they believed it wasn’t important. Hopefully, I will have some good news to share with the group soon. :crossed_fingers:

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