Well, I don’t know if this would help you feel the effects any less, but High Intensity Training (HIT) is based around maximizing results from minimal work… you may find some relief here. Of these methods, I’ve used DoggCrapp, Fortitude, and am currently running Jordan Peter’s Full Body>PPL progression - all of which use a HIT approach.
I used to do a ton of volume and did pretty well, but when I switched to HIT, I saw a big improvement in gains.
This took a little over a year and some dieting, but this all happened with HIT training. It’s not the only answer, but it’s really worth looking into for the reasons you’ve described in this thread.
Wish I knew the answer here - honestly I don’t. I do know that certain peptides are very beneficial for ‘recovery’, but I cannot speak to how well they help the brain ‘recover’. BPC-157 may be worth looking into (I’m assuming by your physique that you’re in the sphere of ‘enhanced’).