The Systemlord Callout Thread

Isopropyl alcohol is a solvent. Ethyl alcohol is the type of alcohol contained within alcoholic beverages

Don’t drink isopropyl alcohol… don’t drink ethanol either…

Alcohol is one of the most harmful recreational drugs available. People make the excuse “but you can have one drink, the same isn’t true with cannabis or whatever”… BS, not true, the prospect microdosing exists for just about every psychoactive substance in the book

Not going to go on a tangent though lol

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Don’t be a dick systemlord. I deadlift 2.5 times my weight and can run a 6:00 minute mile. Social health is very important too. No judgement on pot from me either. Everything in moderation is a very useful tool to elevate life.

Hoping this message came off as playful. Not sure how it sounds when it’s read haha

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But to answer your question… Yes

But the advertisements… the advertisements

Honestly, it was these kind of advertisements that rather than acting as an effective deterrent, pushed many away

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I tend to not use emojis so it’s hard to tell if I’m serious, I was totally being humorous. I never acquired the taste for alcohol and if it hits my tongue I want to puke.

That doesn’t mean anything. Water is quite a powerful solvent and will dissolve more things than any other liquid.

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It is a poison though, inducing dose dependent extensive toxicity

The entire post was not to be taken serious.

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LOL this thread is like the definition of roid rage

People who misuse anabolic steroids report more anger than nonusers,80 as well as more fights, verbal aggression, and violence toward their significant others,81 sometimes called “roid rage.”

It’s dependent on the compound though

Clinical data showcases testosterone, even when administered within supraphysiologic dosages doesn’t alter manic scores, subjects didn’t feel as if overall levels of anger increased… nor was a behavioural alteration detectable (600mg for 10 wks)

Another study found 600mg for 6 wks induced symptoms of mania for a very small subset of subjects… literature is typically rather flawed in that it groups all AAS into one subgroup. Same goes for literature which stipulates AAS are commonly faked… I’ve read it all, but I’ve never come across TESTOSTERONE (not synthetic derivitaves) that was faked… underdosed, unsterile (very rare) yes… but very few labs fake testosterone (there’s also boards that review different UGL’s, not getting into this now, but there’s slightly more quality control than the medical community would have you believe… albeit nowhere near what you’d get on a pharmaceutical level… although some UGL’s operate in a grey area of legality… their products are legitimately sold as prescription meds in third world countries, yet they also make it onto the black market, sometimes the manufacturers are complicit within this practice)

Lumping ALL AAS and stipulating “roid rage” is like saying “drugs will kill you” but not differentiating between marijuana and fentanyl

There ARE certainly compounds prone to making users aggressive

  • masteron
  • fluoxymesterone
  • trenbolone
  • nandrolone (because there is data regarding the administration of nandrolone inducing increased aggression)

But this hasn’t exactly been demonstrated with test… I’m sure it may occur within a select few, however anecdotal reports and data would generally suggest testosterone doesn’t induce anger

Also pertaining to test being faked… I’ve probably had bloods taken from half a different UGL products (TNE, test prop, test E/C, it’s never come out fake or underdosed compared to my stuff on script)

If you’re wondering why I’d choose to go UGL sometimes for testosterone when I’ve got a perfectly fine dose on script (140mg weekly)… it’s because picking up a script is rather expensive at times, there’s always the dirty looks, people questioning me etc. I don’t wish to be punished for having a legitimate medical condition.

Also, just an anecdote… I haven’t been in a fistfight since I was about fifteen… prior to getting on TRT/using anything. Masteron made me slightly more irritable… feel angry at times when people would try provoke me which made it considerably harder to walk away (dropped it because of this)… it was either that or because things in general have been somewhat difficult recently… not important… my anecdote aside from fighting was, as a preteen/young teenager I was far angrier than I am now.

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Wonderful, isn’t it? Anytime someone has to make a statement as I have we get accused of roid rage. Could I have not made the same statement while not on TRT? Yes. What difference does that make? My TRT protocol has zero impact on the topic at hand.

Super interesting study with T levels in the 2000s

‚We found that administration of testosterone caused participants to punish their opponents more frequently than those administered placebo and that higher testosterone levels were specifically associated with increased punishment of opponents who made unfair offers. Importantly, this punishment was costly to the participant and could not be used as an instrument to coerce their opponent into offering them larger amounts, because their opponents’ behavior was known by participants to be predetermined. Thus, unlike previous studies, we can conclude that testosterone can indeed cause male aggression (13) and that this aggression was not mediated by an increased motivation to maximize task earnings or altered beliefs about the strategic influence of their actions on others (33).

Testosterone has been suggested to selectively potentiate aggression that is reactive, or in response to provocation (30). Our results support such an interpretation, showing that, in the absence of provocation, as when they received large offers, participants in the treatment group were not less likely to reward these offers than those in the control group. Rather than giving rise to indiscriminate aggression, testosterone seemed to intensify aggression in social contexts where social status may be under threat. This effect is consistent with the idea that testosterone-induced aggression may be a tool to achieve social dominance and garner reproductive opportunities (13).‘

https://www.pnas.org/content/113/41/11633

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These ads are both ridiculous and somewhat accurate. I’m pro decriminilization of marijuana. But an honest accounting of It’s pharmacology and side effects makes it clear that it is not as benign, nor as beneficial, as many want us to believe. There is a significant correlation betweenthe incidence of psychotic episodes and long term high potency cannabis use. And the prevalence and availability of highly concentrated medical marijuana products will only exacerbate this. It’s efficacy with respect to things like pain, which many people report as their reason for using, is questionable. People jump on the ‘well its better than being addicted to opiates!’ argument. While that is true, it doesn’t mean it’s necessarily the next best option. Those with a co-diagnosis of a mental health disorder (a significant portion of the population) should be very careful. Not to mention that the long term effects on memory from consistent use are proven across the entire population. The latest research I’ve seen showed that users are more susceptible to being coerced to believe events that never happened and fabricate facts. Personal anecdote, I just ended a relationship with my fiancé. There were many issues. But she was also a legal medical marijuana user. And I could tell the change in her when she’d had too much. She was naturally prone to jealousy and relationship paranoia. But it was compounded by the cannabis use. And was one of the driving factors for the end of the relationship. One of the biggest issue with the exploding field of medical marijuana is that there is very little guidance on dosing. With my TRT I take the exact same amount everyday and use the least amount that produces the best outcome. On the surface, there may be some merit for the use of marijuana for a variety of ailments. But if X is the amount for adequate relief, many use 2X, 3X, 4X because there is very little guidance on dosing. And it gets them really high and they like it. So we’ve just created a new group of medically emboldened drug abusers.

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If you don’t stop posting about roid rage, I’ll kick your ass.

Kidding (obviously)

Though it is detracting from the purpose of the thread… Kinda.

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Not necessarily. The point of the thread was to highlight systemlord’s misguided and one sided ‘lower your dose’ ‘worry about estrogen’ argument. The conversation has morphed into a discussion on respecting the upper bounds of dosing with Testosterone(and other compounds). There are proven side effects and consequences. To suggest that a substance who’s very purpose is to impart virile characteristics wouldn’t, in high doses, amplify those same characteristics seems misguided.

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I see no connection between testosterone in the 2000s and TRT levels of 1000-1500 that most of us have when optimized

2000s and above is a bodybuilding range

Fair enough

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I’ll respond to this as some of you’re points

  • psychotic episodes (tends to be largely dependent on genetic predisposition)
  • cognitive stunting

Have been debated as to whether they occur or not within medical literature, and if they occur tend to be dependent on heavy, HEAVY levels of abuse

I support full legalisation/regulation on the notion of “if alcohol is so much worse… which it is, I can create a new thread and link like 100 studies within relation to even occasional heavy drinking inducing statistically significant, measurable cognitive deficits… why should I be fined or criminalised for cannabis?”

This isn’t appropriate conversation for this thread. Though it’s a conversation I’m very interested in having, therefore if you wish to talk about this we can make a thread on the off topic forum or speak via email :slight_smile:

I don’t condone frequent, heavy usage either… a new study has come out linking regular usage to deleterious morphological cardiac alterations with an associated sub clinical decrease in function/output. Whether it’s due to cannabis alone or the fact that the majority of non Americans unfortunately mix with tobacco is unknown.

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One injection…would have been even more interesting to see how these guys did with the game at the end of the week, at trough, comparing results within the subjects. Also, wish they would have put them on a normal TRT protocol and followed them for several weeks. Also, they played a game, it would be cool to somehow measure real life actions and decisions. Not sure what that could be, business decisions, financial, stepping out on committed relationships, etc.?

Appointment 3: Injection.

At the third appointment, participants received a single i.m. injection. Participants in the treatment group were administered a 1-mL dose of testosterone enanthate (250 mg; Androtardyl/Testoviron Depot), whereas participants in the placebo group were administered 1 mL saline; i.m. testosterone enanthate is a long-acting ester of testosterone. The pharmacokinetics of testosterone enanthate yields supraphysiological testosterone levels in serum as early as 2 h after injection, reaching peak levels four to five times above basal between 8 and 24 h after injection (72, 73).

Appointment 4: Testing.

At the fourth appointment, which took place on the following day, blood samples were collected for the measurement of serum testosterone concentrations. These samples were collected 17.5–20 h after the injection of testosterone or placebo. All participants were then given oral and written instructions for both the modified UG task (Fig. 1) (detailed below) and a gambling task not presented here. Participants rated pictures of the proposers’ faces for trustworthiness, dominance, frustration, angriness, friendliness, happiness, and attractiveness and played a short practice session before undergoing MRI. The scanning lasted ∼80 min (15 min of anatomical imaging and 65 min of functional imaging), during which participants completed both the modified UG task and the gambling task. After scanning, participants again rated the proposers for trustworthiness, dominance, frustration, angriness, friendliness, happiness, and attractiveness and completed the SADI, the BDI, the POMS, the IPIP, the Mach IV, the EPQ-R, the BAI, and the certainty equivalents task. Participants also reported whether they believed they had received testosterone and described the effects that they would expect testosterone administration to have on themselves and others. Participants were paid their summed earnings from the UG task, the gambling task, and the outcome of a randomly selected trial from the certainty equivalents task or €80, whichever was greater. The analysis of the neuroimaging data will be presented in a separate paper.

Appointment 5: Medical Follow-Up.

Finally, participants attended the endocrinologist again 4–6 wk after the injection. A physical examination was carried out, and blood samples were collected and analyzed for hematocrit, lipid profile, PSA, liver, renal profile, and hormonal status to assess any potential changes after testosterone administration. Paired sample t tests were used to compare the parameters at baseline and follow-up. There were no significant changes in hemoglobin, hematocrit, total cholesterol and its fractions, and PSA concentrations after either of the injections. Two men enrolled in the study reported pain at the injection sites, which fully resolved after 2 d. One participant in the placebo group reported increased libido after injection. Participants were paid €50 for attending this appointment.

Firstly

  • ONE SINGULAR injection (vs repeated 600mg dosages for ten weeks)
  • small sample size (as was present within the studies that I referenced, but didn’t link)

We now have data that conflicts, further follow up studies are required to acquire a consensus of plausible certainty

Rodent models would agree with the notion “Testosterone induces aggressive behaviour, but stanozolol/certain other compounds don’t?”

Given rodents have differing metabolic/elimination pathways, generally have far less restraint/more disinhibition compared to a human, results can’t be garnered with 100% certainty regarding “this is what happens to humans”. I’d agree perhaps there may be a net impact on mood (neurologically the effects mediated by sex hormones, metabolites of sex hormones etc are very powerful)… however I don’t think that @dbossa having a FT 2x the ref range (say 50) is going to induce a violent outburst. I believe the creation of this thread is in response to building frustration with systemlord that had been present for a while.

I’ll say this though, higher dosages tend to make me more prone to irritation when provoked… but it doesn’t appear to dramatically change my response. I believe some people have more inhibition than others, I’d say I’m of the more inhibited types. Even when say… I’m drunk, I won’t say wildly inappropriate things/make TERRIBLE decisions like many do. I tend to always think meticulously of the potential consequences that may stem from my decisions.