Testosterone Replacement and Estrogen Levels

[quote]ChrisM wrote:
KSman wrote:
SERMs are selective estrogen receptor modulators. These are chemically estrogens that block E in some tissues and may act like estrogen in some others. Using a SERM will make the estrogen receptors in your breast tissue unable, less able, to react to your E2 levels. SERMs do not lower E. In guys who are not on TRT, SERMs can be expected to increase E2 levels. AIs reduce E levels by reducing T–>E aromatization rates. You can reduce your E2 to E2=22pg/ml by increasing the anastrozole dose by: current dose * (current serum E2 / 22 pg/ml). This calc will also reduce your dose if current level is < 22pg/ml.

The SERM will help shrink the breast tissue and it will be short term use. The breast tissue needs to be estrogen starved. Lower E2 levels may not be enough.

I had to stop the Adex due to joint sensitivity and pain. Tried a short dose of Nolvadex but it also bothered my joints(I hope that this is what’s bothering my joints)…
I decided to stop all AI and blockers beacuse I’d rather be able to work out without joint pain and if the gyno gets bad enough, I may consider surgery.
Is joint pain that common of a problem with Adex and Nolvadex? I’m assuming that’s all the choices I have??
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The last time I “od’d” on adex, I had an on demand erection that just wouldn’t finish. My woman was happy time after time, but I was not. I also had elbow pain that was getting pretty ugly, and even though the pain is gone, the creaky poppy joints are still acting up.
I am currently on 2-1/4 mg’s of adex tabs a week, and I feel “normal” again.
If what you have is gyno, you need some dosage of adex to at least help keep it in check. This time be conservative with your dosing as it takes about two weeks for adex levels to even out. So a good plan is take the same dosage for a month and see how you feel. If you feel better but not great, take a slight increase for another month and then check how you feel again.