That’s what a lot of guys say. I sometimes will feel great 8-9 days after injection.
If I’m not mistaken, robroy was saying that too.
Yes and not only that. At times the sudden reintroduction of a bolus I feel great the next day as well.
Just took 4mg of Estradiol 2mg tablets. Going to see how i feel, dont plan on taking this dose daily, but because of low e2 symptoms (mainly dry, painful joints) i wanted to give myself a little boost, will see how i feel and keep this log updated. Hopefully this can help offset the lowering effects of Tadalafil and Vitamin D, which are the 2 meds that i want to keep taking that lower my e2.
Friday, took 6 total MG. Saturday took 4mg total. Complete joint pain relief by Sunday AM.
I’m 17 days into taking estrogen at 2mg.
I haven’t felt much of a difference, but I wouldn’t say it’s doing nothing. I have a been sexually active, and I have the motivation to do it. I still need cialis and levitra, that will probably never change. But when I do take it, I get horny.
I compare this to the times where I was completely numb, like I didn’t even want to pursue women. It could be the estrogen, or it could be that I’m less stressed over work, etc. Still too soon to tell.
I’ll put it this way…on a scale of 1-10, my libido at my worst (most of the time) was a 1. Now I feel like I’m at a 2-3.
I won’t say it’s estrogen yet, I have to be on it for longer to truly find out. In review, I’m taking 100mg weekly test and 1,000ius hcg twice weekly. I’m going to see if I can get test pushed up to 120mg weekly.
I’m going to do at least 30 days of 2mg estrogen. If there isn’t much difference, I will start 4mg.
As far as estrogenic sides…I have zero. I don’t think anyone is at any real risk with a 2mg dose of estrogen. I feel pretty much the same.
the wikipedia article says that at 6mg per day, you will triple your shbg. From the studies in PCOS women it seems that even after discontinuation the SHBG will stay roughly within the same ballpark, so idk if your problem is your SHBG (havent read all your posts) but if it is, you might wanna bump it up to 6 and take it for a month and then see what happens when you get off of it
I just bumped it up to 4mg the other day. Still not feeling much different but I’m not in the weeds.
The thing that amazes me is that I’m not getting sensitivity in my nipples. When I first started taking testosterone (500mg weekly) years ago, I needed an ai.
Now I take test at higher doses and have no issues with gyno. Even when taking estrogen I have zero issues. It must be desensitization to estrogen.
same here, maybe its because of the high conversion to estrone, idk how that binds to or affects breat tissue but that might be the reason
apparently almost everything of it gets converted to estrone so theres only a little bit of actual estradiol as a result, so probably even with higher dosages youre likely never gonna get to a problematic level of actual e2
or maybe the estrone has a higher affinitiy to the breast tissue? idk
This is by far the most amazing thing. Thanks for the data.
Any updates on your end? Did you see any results from moving to a once-a-week shot? Did you pick up estradiol again?
If you were to do volumetric dosing for Estradiol Valerate, what solution would you use to dissolve it? I used Everclear 95% alcohol, but the contents did not dissolve, even though the product information says they could. Am I missing something?
Product Information: β-Estradiol 17-valerate
Chemical Information Estradiol valerate
That’s interesting. I’d love to try it, but I can’t seem to find any. Could someone tell me where to find it in Canada without a prescription?
No, I decided to go the plant medicine route as nothing in my hormone therapy was working despite having perfect numbers. I did my first retreat in December '24 with three ceremonies and it was pretty underwhelming cause nothing happened.
I went back home and about a month later, I noticed that my sleep had improved and I was waking up full of energy and ready to conquer the world. I had so much energy that I was going to the gym twice a week.
I stopped taking my sleep medication and I was still able to sleep and even reintroduced morning coffee! My sleep is still trash but it is significantly better than the misery I was living with prior taking the plant medicine.
I decided to go back for a second retreat in the last week of February '25 hoping it would permanently fix my sleep which will hopefully lead to symptom resolution of all my other problems.
If the first retreat is any indication, I anticipate to see some changes one month after the retreat and I am approaching the one month mark at the end of next week.
I booked a third retreat for the first week of May '25 and really hope this shit works!
Came across this thread and figured I’ll try this experiment.
A little background about me:
June 2022 - Oct 2023 I was on TRT. It was a disaster top to bottom. Other than muscle and fitness, I had every side effect under the sun. Tried all different dosages and protocols yet couldn’t resolve anxiety, high BP, libido, ED, acne, insomnia, etc.
Oct 2023 - May 2024 I felt so miserable on TRT that I had no choice but to PCT and come off. Bloodwork was good, and most symptoms resolved themselves pretty quickly, but libido and acne persisted.
May 2024 - Today I’ve been on Nandrolone and hCG (no Test), and while I feel SO much better than on Test, libido and sensitivity are really the only things lagging. EQ is great, but sex feels pointless when there’s almost no pleasure associated with it. While I do feel mental benefits from hCG, with regards to sex it does practically nothing. The first month I ever tried hCG was the only time that it worked for me as expected; sex/orgasms/load sizes were all like normal. After that, garbage.
I got some sublingual estradiol yesterday and plan on taking 2mg/day for the next few weeks as an alternative to hCG. Stay tuned.
Well, it’s been 10 days. There’s definitely an improvement in libido and my testicles have reinflated to their former glory. Still waiting for improvement in sensitivity and orgasm quality, but there is hope. I’ll be getting bloodwork in the next few weeks to see what’s going on.
Super interesting. So you’re only doing HCG + sublingual estradiol? What dosages and frequency of both?
I’m doing 150mg NPP and 1,000iu hCG split 2x per week and 2mg sublingual e2 daily.
Some notes for context:
-I do have prescribed Deca but, even though they’re technically the same, I’m afraid to change anything because I’m feeling good on NPP.
-I also got prescribed compounded e2 cream 0.25mg 3x a week. I haven’t received it yet. Not sure if I’ll make the switch when it arrives. TBD. The sublingual e2 I’m using now is UGL.
How come you’re on deca?
I had a terrible time on Test and after coming off for 8 months some symptoms never resolved themselves. I had no choice but to try something. NPP ended up working well for me.