Read about it aswell.
No idea mate, so many theories in my head now but that might be it!
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I can confirm adderall doesnāt quite have that dopamine hit like it used to. And I donāt mean desensitization due to chronic use. A once in a while pill does still have a kick over all, that rush of dopamine just isnāt there.
Permanent desensitisation
This study showed higher test and lower e2 with subq though:
I know, Iāve seen that one though.
Meanwhile among all this discussion Iām actually starting to have success by raising my dose high enough to tolerate taking an aromatase inhibitor.
Kept crashing your E2 before?
I was always trying to keep my dose at 140ish or below so even .125mg of anastrozole or 6.25mg of exemestane would crash it.
I tried the whole lower dose, frequent injection thing for years with many combinations of dose and frequency with no symptom relief. I tried the whole let the E2 ride as high as it goes thing for years too. I know I feel better and start getting symptom relief on the higher dose, but libido issues persisted as well as anxiety with the higher E2 which I didnāt even realize at the time.
Now Iām up at 200mg a week with the lower dose AI and I feel like Iām getting all the benefits. Libido and erections are not 100 percent yet but much better than where they were and Iām going to give it the full 8 weeks and see how I do/run labs.
I suspect that I convert just slightly higher to estradiol than is optimal for me, probably given the steady state levels, and that actually raising my dose high enough to tolerate the low dose AI is taking the edge off, so to speak.
I am similar to you but can never figure out the right regimen long term when it comes to higher dose + AI.
Who knows if Iāll be able to dial it in perfectly, just know itās an improvement overall so far. I tried a dose similar to what youāre on now for over a year and felt terrible unfortunately.
I believe that taking injectable estradiol possibly was making me hypothyroid. Iām currently thinking of really dialing in thyroid medication and increasing test to see if that helps along with dropping the estrogen therapy for now. Also amazingly Iāve dropped starch and am eating high carb still from juice and honey. All water retention gone within a day. Seeing veins havenāt seen in years.
Since you have low e2 maybe ramping up dose want call for an ai even into blast territory but maybe find relief at some point. Iāve been low dose the whole way myself and never have felt right.
I like the bit about āenough E2 to use an aromatase inhibitor.ā Thats fascinating on its face. Regardless this thread shows that optimizing levels of some hormones in the body is like optimizing some ingredients in a meal. A lot more to it.
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So those clients that where using e2 valerate stopped taking it and there low e2 symptoms never returned?
Correct, none of them stayed on it for an extended period.
What were the parameters to do it? I have a problem in where anything over 100mg gives me problems. The thing is I am not a high aromitizer. If their E2 was above 20 did you still do it?
My girlfriend has a month of unused Loryna left over, not sure if I should try that due to the added diuretic.
None in particular, but if I recall those that took E2 were in single digits prior to starting testosterone and did not see much of a boost from just testosterone.
Maybe.
Why ya guys so afraid of taking some estrogen, nothing bad will happen LOL, just take it.
U too high inhibition, u just need to try fucking shit til it all sticks
Dont think too much, just do
DO DO DO DO DO DO DO
Only simply because the birth control I can get access to from my girlfriend has a diuretic in it as well.
make sure its only estradiol, no damn weird progesterone shit etc etc