Start of Experiment: Estradiol Valerate

My problem with higher dosing honestly I am learning is ED, physical. Not libido, not mental, as if anything the libido is actually there.

Although when I initially go higher dose it’s the best result, but just at start.

This is such a common issue in the TRT world in my opinion. Initial increases in dose almost always feel good. Then a few doses later the problems you were seeking to solve can get worse. It can lead to “chasing the dragon” at the higher doses that never really offered any benefit besides a quick dopamine boost and initial hormone spike in the first place.

This is where my confusion about all the supposed goodness of E2 comes in mind. I raise the dose, E2 is technically lagging, I feel good until I don’t.

I lower dose, E2 lagging now to come down, I feel better eventually.

So the assumption is more E2 for me is not the next best thing since sliced bread.

The more E2 is better thing was most likely a result of the pendulum swinging back in the other direction in the rise of TRT clinics crushing estrogen with the over prescription of arimidex. E2 is definitely beneficial but I have a feeling that once you’re outside of what’s roughly normal range, it’s more of a matter of how much you can get away with tolerating, than any additional benefits gained simply by running it higher (for the average person)

How you feel when you also take an AI?

Better short term, can never dial it in long term or very risky game with crashing my E2.

I wrote my last post quick but I forgot there is also the possibility that it just may be too much T/androgens all together and initially I feel good until full saturation, and then desaturation in reverse. To be fair and play devils advocate that can be the case too. But how can people feel god like doing full on cycles then is beyond me. Why am I so special that just higher doctor regulated TRT protocols are a no go for me?

Perhaps people like you and I are androgen sensitive enough that lower doses give the stimulation needed that other guys get at the more common clinic dosages, and that the higher doses give us much higher saturation/stimulation than other people so we run into issues sooner (purely speculation). Also tons of people ignore sides or take tons of other meds to feel good running higher trt dosages.

I’m using an AI with higher doses now and although it’s feeling good and I’m going to stick it out until I get labs, it definitely is not as good as running lower doses like I have in the past. ED is more hit or miss because there are more moving parts and arimidex can crush and rebound estrogen quickly. I can see how I would feel “good enough” and tolerate the sides for a cycle, however, even a decade ago when I felt “good” running cycles, it was such a sense of relief to come off. You don’t realize how much you’re redlining your body at bodybuilding dosages until you come off. Kinda like how guys don’t realize how much drinking or tons of fast food was messing up their gut until they cut it out, etc.

Would this experiment work with estradiol hemihydrate?

Not sure some of us are special. I am at 63 mg/wk and feel overall much much better than when on 80 mg/wk. Getting labs in the next few days since it has been 10 weeks since i lowered. Erections are light years better too, tons of night wood. Head is clearer and workouts better. I think because we are on this site we feel we are laggards or something. Maybe we just don’t know all of the sides others are feeling? What you can tolerate (100 mg/wk?) would render me functionless.

Lot’s of people on excel male at much lower doses than people claim here. I don’t necessarily think being able to tolerate large doses translastes to strength. I could care less if my bench dropped 15% or whatever. If I feel good then I am satisifed with my TRT

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Might just be sum else.

Try inject 1g for a couple months, then ull figure out if u are really that “androgen sensitive”.

My money is on, u not

I have in the past. It’s overkill for me. I feel sick on that high of a dose.
Also don’t mistake androgenic activity with anabolism as far as hyper responsiveness for muscle growth which has a ton of other factors besides testosterone levels, I’m not talking about hypertrophy.

Ye probably just me getting accustomed to it being a roidhead LOL

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I’m glad you’re enjoying it and having success lol makes me miss the old days.

@Robroy

Did you ever get blood work done at any point. I’ve had libido issues after 1 month of taking gear (which was over 10 years ago) - Battled with every TRT dosing schedule with no results. I am going to try this protocol, I am just waiting on my Valerate being delivered.

Out of curiosity, did your SHBG improve?

I recently heard a theory that as SHBG comes from the interaction in the liver with E2, conversion from test to E2 does not pass through the liver for some due to the higher androgen, by taking it orally it stimulates SHGB directly from the liver and in turn raises SHBG resulting in a higher libido. I always thought my low E2 was the culprit but after mega dosing HCH I was able to raise my E2 but no libido improvement. The only constant is my low SHBG (SHBG - 8 (18.3 - 54.1) nmol/L

I am just curious what the bloods looked like after taking. I am going to try it regardless, I am absolutely certain that E2 is the key to libido and EQ but I suspect SHBG might be the glue that holds it all together.

Great work on the log btw - You’ve given me some serious hope as this libido crap has been ruining my life for years.

Always low shbg. 18-20 BEFORE TEST, after that around 8, sometimes 12.

Yes, it might be that e2 increased shbg, i dont know yet.

I REALLY DO BELIEVE that might be the case, actually. As low shbg people OFTEN OFTEN OFTEN have problems with libido on gear.

Try up it with t3 or t4 or whatever it is, also try CLOMID for it, see what happends. Clomid gave me great erections aswell!

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Oh theres hope for sure, its just machinery basically, or a robot. Put in the right code and it works, lmfaoo

You sure it’s not just all in his head? Maybe he just needs vitamin E and high dose omega 3s?

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Maybe he compensated for his heterozygous MTHFR mutation by eating enough leafy greens three weeks ago, finally corrected his elemental boron deficiency and only faps to girl on girl now.

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Yeah, right right, more bananas and potatoes will do it.

No but srs, yes, my shbg was always low, natty around 20, on trt down to fucking 8, 12 etc. I know estrogen increase shbg, so maybe thats the reason, I DUNNO MATE, I JUST KNOW IT WORKED

TRY IT OUT BOYOSS

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Are you still off the EV and doing well or back taking it?