Puts you at higher risk for clots if it’s not your own E2.
Really? is it the same for women on birth control?
Yes. However the risk increase isn’t terribly significant.
Isn’t bc typically estrogen and progesterone? I think that might make a difference as progesterone can oppose estrogen and can be given in women experiencing estrogen dominance.
I’m the same. I’ve run 750mg test weekly with no AI, but around 240mg-360mg I need to control e2 for sure.
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Makes me think its possible to overwhelm aromatase. After all, 50 soldiers might put up a sustained fight against 100, but 1000 would make it perhaps not a fight at all.
The more testosterone = the more work to do
Regular amount = work gets done
High amount = lots of work gets done
Super high amount = workers exhausted before more workers arrive, work piles up
I mean aromatase is made too. If the amount of test is always enough to be handled by whats on-hand, youd get a dose dependent cascade of effects based on whatever ratio. If aromatase gets used up faster than its produced, the bottom of that ratio freezes and the top piles up.
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I think this is reasonable. If you crank you FT up, eventually all or nearly all of the aromatase enzyme will be saturated by FT.
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Side effects would still happen on large doses, but perhaps be caused by the original population of aromatase in full effect, NOT an infinite % scale of testosterone being aromatized. Some sides also could be affected by more testosterone acting in concert with whatever. Could be why many guys on massive doses dont need commensurately massive AI but many on moderate doses benefit from something.
Something like:
50mg: low t/e effects
100mg: t replacement, no e effects
150mg: upper range effects, positive benefits of more t and more e
200mg: anabolic benefits, begin erectile dysfunction
300mg: begin gyno
aromatase exhausted_
500mg: roidz zone, but AI usage should “complement” or consider the 200-300mg range where aromatase activity started side effects
1000mg: same as above
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This is something I thought about a few years ago when thinking about some of the reported doses used by competitive BBers and strength athletes. Like how can they be running 2-3g of Test a week, and not have E2 issues, or not popping adex like skittles. When I saw the E2 response to FT graph (it not being linear, and leveling out), it made a lot more sense to me. It was a light bulb moment. Same for DHT. Like how do some of these guys have any hair. The thing is their DHT did go up, but more like double that of a strong TRT dose, but they are using 10X that strong TRT dose.
I don’t seem to be very sensitive to E2. I seem to be able to run a whole range of doses from TRT to a pretty high cycle dose of Test without high E2 issues.
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I noticed a few early posts saying that Estradiol Valerate is just birth control… I’m pretty sure most birth controls are multiple different forms of different hormones. I don’t even think Estradiol Valerate is sold just as its self as birth control. So I would probably advise against just picking up random birth control to try this.
Correct me if I’m wrong anyone.
Correct. Theres combined ones thats progesterone and estrogen. And progesterone only.
Any updates @royrob ?
No news, no labs yet, just insane libido, consistent.
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How long have u been doing this now?
And how long are u planning on doing this?
Looks like something i would defenitly like to try… but i dont see how i would get my hands on estradiol valerate without a prescription here in europe 
Since around september, probably forever, gon check bloods soon enough i think.
Libido is thru the roof.
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Can’t wait to see your bloods!
Updates?
I tried this for 21 days. Usual terrible side effects from high estrogen (bloating and increased anxiety) and no increase in libido. Also got what appears to be permanent skin tags from it. No bueno.
Note: I’m not on a cycle like @Robroy
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Crazy how individual this is.
I even tried 6mg a couple of days.
Only thing that happends is i get tons of nostalgia, thining about the good old days as a kid, wanting to go back. But no acne, no anxiety and no bloating.
I guess we’ll see when you get bloods. Based on past blood work, if i was running Test at 300mg per week, my trough blood levels on a twice per week schedule would be around 2400 ng/dl. I’m guessing that you’re a low converter so your E2 couldn’t keep up with your Test. Will be interesting to see your ratio.