This natural compound boosts longevity and sexual health. That's a win-win.
There are supplements for better sex and there are supplements for better health. These categories sometimes overlap.
Punicalagin is a multitasking ingredient that fits both categories.
What is punicalagin?
Punicalagin ➔ Buy at Biotest is a type of polyphenol found in small amounts in pomegranates. It's both a health/longevity supplement and a bedroom performance booster. Here are some of the ways punicalagin or its metabolites support both goals:
1. Punicalagin is nature's Viagra
Punicalagin elevates levels of nitric oxide (NO), which relaxes the smooth muscle fibers of penile arteries so they allow more blood to flow into the penis. A double-blind crossover study with 61 male subjects found that 47% reported improved erections with punicalagin.
2. Punicalagin keeps blood vessels healthy
Punicalagin can raise levels of NO, which opens up blood vessels, but it also improves circulatory function in general through its powerful antioxidant capability. Multiple studies show that it enhances blood flow and even reverses arterial plaque growth. (Roto-rooter out the plaque and you automatically improve blood flow.)
As a bonus, erections are all about hydraulics, and if the “hoses” (blood vessels) are strong and clear of gunk, they provide a lot of the pressure needed to initiate liftoff.
3. Punicalagin blocks testosterone-to-estrogen conversion
The parent compound and its metabolite are powerful inhibitors of aromatase activity, which means punicalagin thwarts the conversion of testosterone into estrogen, thereby elevating T levels naturally.
One study of men and women found that punicalagin raises levels of testosterone by an average of 24%. Punicalagin blocks the conversion of testosterone to DHT and inhibits the 5-alpha reductase enzyme. This results in less testosterone being converted to DHT, thereby promoting a normal PSA level and preventing prostate growth (thus making it easier to pee).
A new superpower: immunity support
Researchers recently uncovered another benefit of punicalagin: stronger immune defense.
After passing through the gut, punicalagin is converted by bacteria into ellagic acid and then into compounds called urolithins. These compounds strengthen immunity by triggering mitochondrial autophagy in T cells, clearing out damaged mitochondria and replacing them with new ones. The result is rejuvenated T cells that function more effectively.
In studies, this process restored the activity of tumor-fighting T cells that had become suppressed, allowing them to attack cancer cells again.
Even better, many of the resulting cells were T memory cells. Once these cells encounter a pathogen, they remember it, producing faster and stronger responses if it returns.
One complication is age. Older adults produce about half as much urolithin due to microbiome changes. But consuming punicalagin can restore meaningful urolithin levels, helping the immune system stay sharp.
Where do I get punicalagin?
You might be thinking about chugging pomegranate juice to increase your punicalagin intake. Unfortunately, punicalagin is mainly present in the root, bark, and leaves of the pomegranate, none of which is used to make commercial pomegranate juice. You'll get a little from the juice, but not enough for a pharmaceutical-like effect. The best way to augment your intake of punicalagin is to take a supplement.
Punicalagin is the backbone of P-Well ➔ Buy at Biotest. Each serving contains 180 mg. of punicalagin (from pomegranate), along with 30 mg. of lycopene and 500 mg. of cranberry whole fruit concentrate. That makes P-Well a multi-functional supplement for vascular sexual health, urinary tract health, prostate support, and now, based on the latest research, a powerful immune-enhancing supplement.
Does it work for women?
While women of course don’t have prostates, P-Well provides many other beneficial effects to female vascular sexual health and urinary tract health, as well as providing a host of other health benefits, none of which are gender specific.
