Punicalagins: The tomorrow molecules

[Biotest]

Start taking this supplement today and your future self will thank you.

Here's an interesting training philosophy: Train today for how you want to feel when you're older. If you want to be strong, healthy, and mobile in the future, think about how today's workout contributes to that goal.

We could say the same about supplements: Supplement today in a way that makes you healthier tomorrow. So, what can we take today to stave off many of the issues that come along with aging? Emerging research points to punicalagins ➔ Buy at Biotest.

What are punicalagins?

Punicalagins are ellagitannins, bioactive polyphenols primarily in pomegranates. And all of those health benefits you get from pomegranates? They come from its punicalagin content. The only problem is that getting enough punicalagins from pomegranate juice is almost impossible. But we'll get to that below.

You probably know about the two major benefits of punicalagins: erection health and prostate support. So, here's a quick summary, plus some emerging research on punicalagins and longevity.

1. Punicalagins vs. prostate issues

Prostate issues are now affecting more men and starting at younger ages. Even if successful, modern treatment modalities lead to sexual side effects. Punicalagins can help:

• Punicalagins help reduce inflammation in the prostate gland. This protects against oxidative stress and important for maintaining prostate health.
• Punicalagins promote healthy new-cell proliferation.
• Punicalagins help maintain healthy prostate size by processing, conversion, utilization, and clearance of sex hormones.

2. Punicalagins vs. limp noodles

Here's a benefit with immediate and long-term effects: punicalagins help you get it up and keep it up.

Punicalagins improve endothelial function. The endothelium is the layer of cells lining the interior surface of blood vessels. In a nutshell, improved function leads to more nitric oxide (NO) and better blood flow to the penis. Strong erections are all about blood flow.

3. Punicalagins vs. cognitive decline (brain fog)

Punicalagins are metabolized by your gut into urolithin A, a compound that improves cellular energy by cleaning up damaged mitochondria, leading to improved learning and memory.

Weak mitochondria build up and affect brain function. A healthy brain is designed to use urolithin A to clean up the weak cells, for optimal cognitive function.

Emerging research also suggests that urolithin A supports synaptic function and promotes the formation of new neurons, critical for memory and overall cognitive function.

4. Punicalagins vs. looking old

One study found that punicalagins reduced signs of aging saggy skin. This is attributed to their ability to modulate skin's elastin (elasticity) and collagen (firmness) by suppressing matrix-degrading enzymes improving remodeling.

5. Punicalagins vs. fatty liver

Punicalagins help protect against excessive accumulation of fat in liver cells, often caused by metabolic decline.

So, just drink pomegranate juice?

Drinking 100% pure juice doesn't hurt, but it's very difficult to get a therapeutic amount of punicalagins. To get 180 mg of punicalagins (an effective dose), you'd need to consume up to 30 ounces daily. That's over 500 calories and about 125 grams of sugar. So, supplementation is the wise choice.

P-Well ➔ Buy at Biotest contains 180 mg of punicalagins per serving, along with lycopene and cranberry.

Biotest P-Well is designed to amplify nitric oxide, promote reproductive blood flow, fortify prostate and reproductive tissues, keep the urinary tract clean and flowing well, and support the body’s normal processing, conversion, utilization, and clearance of sex hormones.

P-Well ➔ Buy at Biotest

References

1. Siffiqui et al. Multifaceted Neuroprotective Role of Punicalagin: A Review. Neurochemical Research, 12 December 2023.
2. Xu et al. Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases. J. Antioxidants.
3. Pomella Pomegranate Ellagitannins Show Promise In Polyphenol Conversion Capabilities Of Urolithins. Verdure Sciences.
4. Hou et al. Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions. Journal Alzheimer's & Dementia. 16 May 2024.

[TrainForPain]

I have been taking P-Well for a little over a month and just noted in my own log the difference I already feel.

Point #1 has been obvious. I’m not old (42), but I was definitely waking at night to go to the bathroom. The last couple weeks I’ve been able to sleep through.

Point #2… yep.

Point #4-5: I swear my knees and elbows feel better. I’ve noted in some of my workouts I haven’t worn neoprene sleeves (normally a must for me), and I’ve done pretty well. I think I’m getting some benefit here as well. I also take Flameout, but that’s not a new variable, so I think we can chalk some improvement up to the P-Well.