Microdosing Tren on TRT

[readalot]

Yes. Body produces and eliminates free T.

Naturally High Test & Estradiol, Still Feel Awful

The conventional thinking is that higher SHBG reduces free testosterone and causes hypogonadal symptoms as a result. The Sponge Theory of SHBG suggests the conventional thinking is wrong: SHBG only influences total testosterone, and your body will regulate to its preferred level of free testosterone regardless of SHBG value. Regardless of what you believe about SHBG though, free testosterone isn’t your problem here, because your free testosterone values are high normal. You’re at the top of …

We have been discussing this quite a bit here and on Excel Male.

First Cycle Questions for 46Y/O

I won’t link to EM anymore but there are lots of good analogies over there if you take a look @Andrewgen_Receptors The idea of SHBG as a sponge that sucks up large amounts of testosterone and leaves your free T low doesn’t seem to be how it really works. The way I understand it, high SHBG makes your meager production (revealed by the free T) look like it’s normal or even high when it isn’t. The SHBG is basically extending the half-life of the testosterone you’ve produced and the relationship s…

800mg Test Cyp a Week, Total Test Is Only 1406!

TLDR: doesn’t matter. More details that are of probably little help but may interest some. Thought about your question which was reason for delay in responding and trying to answer as succinctly as possible based on the constructive feedback I’ve received recently. I FAILED! If your goal with respect to question is to maximize muscle growth then my short answer is I don’t think it matters. Area under the curve (how much your body processes) will be proportional to dose so whether you do cy…

Naturally High Test & Estradiol, Still Feel Awful

Thanks for clarifying the ranges and units. Good job getting decent fT test through Quest (equiibrium dialysis). More mythology IMO. Intelligent opinion and clinical data indicate HPTA controls free testosterone (fT) not total testosterone (TT) and SHBG+fT yields TT. Hence, if you waved a magic wand and lowered your SHBG your fT would stay the same and TT would drop. I tried this on myself by using medication (oxandrolone) that lowers SHBG. Some additional comments about this: @FunkOd…

First Cycle Questions for 46Y/O

@Andrewgen_Receptors https://academic.oup.com/jcem/article/91/11/4669/2656842 More posts from @cataceous over on my What is TRT… thread at EM regarding paper above. You’d do well to study this if you want to understand. The issue with this study is that they are basing MCR on total T rather than free T. The standard equation used is: Production_rate = MCR * Hormone_concentration But as I argued above, the proportionality applies to free testosterone, not total. So the equation should be: …

Been On TRT For A Year. Is It Time to Add In Another Compound?

@mnben87 Also, here’s a better description of the “apparent MCR” we discussed above. I took some shortcuts in the description. The above is how it would actually work. The paper I mention in the above quote is linked in this post: If you want to read an in depth review go over to ExcelMale and search for clearance rate and SHBG and filter by user “cataceous”. He really goes in depth and it’s a nice summary of the whole thing. Then you get into accurately measuring free T and the typical…