[quote]TTewell342 wrote:
jsbrook wrote:
I think they have been bought out by Clinuvel. But I think Clinuvel just may have the rights to Melanotan [I} which does not have the libido effecs as Melanotan II does but does produce the darkening. Clinuvel plans to have this on the market by 2009.
So, I’m looking around on Bloomberg for this company and i come up with 2 different stocks for Clinuvel. Is it CLVLF or CLVLY that I want? CLVLY is the higher priced stock.[/quote]
I don’t think it’s actually on the American stock exchange yet.
[quote]TONEdef wrote:
TTewell342 wrote:
So, I’m looking around on Bloomberg for this company and i come up with 2 different stocks for Clinuvel. Is it CLVLF or CLVLY that I want? CLVLY is the higher priced stock.
Remember that they are in the tertiary phase of testing with Melanotan. If that goes to plan I’d expect the share price to rocket as soon as the product hits the market.
[quote]T Ham wrote:
Unfortunately, it seems to be mostly in the form of injectable, so you have to learn how to inject.[/quote]
This wont necessarily always be the case. Clinuval are working on one in the form of a transdermal spray and one in a slow release implant, but these will not be available until 2009. Currently the only tried and trusted method is injection, but subQ injections are really not that hard.
I did some researching a while back on this compound when I was looking to invest some how. Heard about it on Dean Edell radio show. It has actually been around for a while, Melanotan II was developed at University of Arizona in the 90s, and they reached a deal with Competitive Technologies (CTT) to handle the licensing arrangements. They licensed Epitan, Ltd. to develop the tanning aspects of the compound, and Palatin Technologies of New Jersey (PTN) to develop the sexual and appetite suppression properties.
Palatin seems to be further along to possible FDA approval than Epitan. The compound they have developed, pt-141, was shown in a phase three trial to have a 60-70% success rate for female sexual dysfunction. They are attempting to initially get it approved for female sexual dysfunction, as this may be an easier route to go politically (their aren’t yet any other effect drugs for FSAD) The results for male sexual dysfunction are reportedly spectacular, like 100% effective. Viagra compared to pt-141 is like Tylenol compared to morphine. Because it works through CNS pathways, it is the only drug that promotes desire for sex, unlike others that work solely on the vascular system. So no heart attacks while on pt-141(or maybe not?). Palatin has partnered with King Pharmaceuticals to develop it, and King may actually have a larger share now, I’m not sure. In any event once it gets approved they probably will have to partner with/sell to big pharma to get it mass produced. I bought 1000 shares of PTN at 2.06. I could lose it if things don’t work out, but what’s 2000 bucks for a potential 30 bagger?
Because Epitan was facing the prospect of getting their drug approved for broad cosmetic/non-essential purposes they decided to first get it approved for treatment of various skin disorders (hence the name change to Clinuvel). It may still be a long while until it is ready for general use for tanning, they need to have it to market I believe by 2008 or they lose the rights.
[quote]TONEdef wrote:
T Ham wrote:
Unfortunately, it seems to be mostly in the form of injectable, so you have to learn how to inject.
This wont necessarily always be the case. Clinuval are working on one in the form of a transdermal spray and one in a slow release implant, but these will not be available until 2009. Currently the only tried and trusted method is injection, but subQ injections are really not that hard.[/quote]
Yeah. It will never have the popularity it could if they only stay with the injection. But in the meantime…how do you inject? And what’s a good online source for needles and a syringe with measured increments? Can someone PM me one?
You can usually buy needles and syringes at any retail pharmacy. However, depending on your state they may require you to have a rx for insulin in order to buy them
Since they’re subcutaneous injections, you could simply get insulin syringes. Look online, you’ll probably find some pretty easily. You can also find quick tutorials online probably on how to do subcutaneous injections. They’re a LOT simpler and less risk involved than intramuscular injections (no risk of hitting a vein/artery and injecting into your blood stream). They probably don’t get as sore as IM injections.
[quote]speed wrote:
Aragorn wrote:
So does that mean a fair skinned viking such as myself probably wouldwes the effect seem to even out and eventually turn into an even tan?
And how long are these individual cycles supposed to last/resulting tan last?
Pardon me, usually I do my reading up first to find what I can, but I’ve got bleeding slow dialup at my temporary summer addy.
No. You would get a solid tan, you would just be more likely to develop freckles than a naturally darker individual would. You might not even get freckles.
The tan will last a while as long as you continue to get some sort of sun exposure. I shot 10 mg/week for about 10 weeks and I still have the tan and i’ve been off for 6 weeks already. But in all fairness, I tan very easily as I’m armenian so I can’t speak for fair-skinned individuals.
[/quote]
That’s a pretty hefty cycle. I don’t think I have a line of credit big enough for that kind of thing at the prices listed earlier . Is that what’s recommended? I thought recommended use was 1mg/injection/day for about 1-2 weeks.
That’s a pretty hefty cycle. I don’t think I have a line of credit big enough for that kind of thing at the prices listed earlier . Is that what’s recommended? I thought recommended use was 1mg/injection/day for about 1-2 weeks.[/quote]
You’re right it is. I used it right when MR started carrying it and I was experimenting with the doses. But yes the recomended use is around 1mg per day for a couple weeks. Either way, it worked fantastic for me. Next time I use it I am going to try more of the recommended dose.
[quote]chrismcl wrote:
Since they’re subcutaneous injections, you could simply get insulin syringes. Look online, you’ll probably find some pretty easily. You can also find quick tutorials online probably on how to do subcutaneous injections. They’re a LOT simpler and less risk involved than intramuscular injections (no risk of hitting a vein/artery and injecting into your blood stream). They probably don’t get as sore as IM injections.[/quote]
It’s pretty easy, right? You basically just pinch a skindfold, and inject into the skinfold being careful not to go to deep, right? 90 degree angle, maybe?
Just thought I’d point out that according to melanotan.org, people ARE experiencing side effects from this. Mostly shortly after the injection. People complain about feeling nauseous, flushed, worn-down, and even getting the shakes. One guy was even complaining about how a couple hours after he would inject, if there would be any movement to his pants, he would get a raging hard-on. LOL
[quote]bushidobadboy wrote:
More of a 45 degree angle, kina perpedicular to the peice of skin as it is pulled away from the body before it gets trapped between your finger and thumb - does that make much sense lol?[/quote]
Back in the day when I tended cattle for a living, we used a technique called “tenting”. You grab the skin between the index finger and thumb, pull the skin aout perpendicular to the body, and inject in the tent you made.
I have never tried this out on a human, or myself for that matter, but it seemed to work really well for the bovines. No absesses, and it no inadvertant IM injections.
[quote]bushidobadboy wrote:
More of a 45 degree angle, kina perpedicular to the peice of skin as it is pulled away from the body before it gets trapped between your finger and thumb - does that make much sense lol?[/quote]
Sounds good. Anybody have thoughts on what size needle and syringe you’d want to use for this product?
I think over on the melanotan.org board they recommend either 1/2 cc or 1 cc syringes. Basically insulin syringes. As for the needle, you can use 28, 29, 30 gauge. Basically the larger the number the smaller the bore in the needle is and the less it should hurt.
I will probably go with 1 ml and 29 gauge when i finally order some
[quote]PharmD Pete wrote:
I think over on the melanotan.org board they recommend either 1/2 cc or 1 cc syringes. Basically insulin syringes. As for the needle, you can use 28, 29, 30 gauge. Basically the larger the number the smaller the bore in the needle is and the less it should hurt.
I will probably go with 1 ml and 29 gauge when i finally order some[/quote]
Thanks. Sounds good. I’m not sure of the pharmacy’s policy in New York where I am this summer. But I’ll probably just order those online. Anyone know how long a bottle of this lasts at the recommended dosage?
[quote]TONEdef wrote:
rainjack wrote:
Are there any reports of bad sides? It scares me when everyoe talks about how great a new product is with no discussion of the possible cons to it.
But with that said - Sounds like a cool as hell product.
As far as I’ve been able to find out, there isn’t much in the way of sides. Some people have reported an increase in freckles and of course with Melnotan II there is increased libido in both sexes. It also has weight loss properties, which can only be a plus point for those who are cutting. It does seem to exert some action on the vascular system. People have also said they’ve experienced numb lips, sore muscles and tingling sensations, but not to any great degree.
Tone [/quote]
Side effects that have been noted thus far:
transient facial flushing and lethargy
but in greater doses nausea and vomiting were reported for the so called MT1. The same is probably true for the MTII.
The developers of these peptides have stated when MTII or PT-141 (PT-141 is a metabolite of MTII) are used for erectile dysfunction they are not likely to increase skin pigmentation or decrease appetite under normal use due to the requirement of prolonged dosing for enhanced pigmentation.
By the way MTI and MTII were developed by somewhat of a “Dream Team” or “Arizona Team” as they like to say. Vic Hruby, Robert Dorr and Mac Hadley are all stars in their own fields. Many who have taken an endocrinology course in the last 20 years might remember Mac Hadley.