I’ve done dailys since my second week on trt
Josh what is your dose again?
When I hit a dose that is too high for me it makes me insanely anxious and crazy paranoid. It’s actually painful until the peak subsides. There is no way in shit my body would ever “get used” to such a dose.
140, I’ve experimented all the way up to 250, and down to 112, I just seem the same level of activated no matter the dosage… Maybe lesser amounts on lower. Gonna try out 100-112 and see from there. Upping my ssris and working on my mental health…
I don’t want to suggest another dose change for you but it could certainly be too high. For me 92mg a week and higher puts me in that awful state while 80mg does not.
If you have it built up in your system you have to give it time because for me a single dose of 80 which followed several 92s would still put me in that state due to half life.
And 80 is still an effective dose for me. In fact 80 is still too high but it doesn’t cause all the anxiety and paranoia.
I will keep expiermenting and researching, I appreciate the input and am not giving up. If anyone has any input on tests affect on the fight or flight I’d appreciate it.
Due to trauma at a bad age, I lived in fight or flight mode for a very long time. It was really bad for my body. I did finally get on top of it but then anxiety appeared again with my Low T which I couldn’t really shake.
I can only say that when my Test is right, my fight or flight only appears when summoned. T has a wonderful calming effect on me, to the point where even shit like getting chewed out or shouted at doesn’t faze me. That effect does not appear right away, but once it settles in, it generally stays until I change my dose.
But I did do work on myself over the course of several years to shed the fight or flight mode, which was essentially PTSD. I honestly don’t know what the PTSD would have been like in terms of anxiety on the correct dose of T had I not done that work years ago. I don’t think it would have cured it. But it may have made life easier.
Thanks I appreciate the insight, mine seems to stem from genes and trauma I guess but I personally don’t suffer psychologically in fear of some certain trigger like most people, just a fear of anxiety itself and full blown panic and constant vigilance. Its tough and exhausting.
I don’t know if I already did this with you Josh, but let me direct you to a post I made over the summer which outlines a technique which may help you deal with your mind and anxiety a little.
Please give it a try. In your situation, I believe every bit helps:
Anxiety aside for a bit…
I went to donate blood due to just feeling like I was wearing a thick blanket, fealt hard to get a satisfying breath. When they tested my hct and hmg at the red cross it said 18.4 - I know these arent that accurate
I tested my hct and hmg about a month ago and it was like 16.8.
My ex told me my snoring was so bad the pictures on the wall would shake, so I am planning to get a sleep study however I have to wait until feburary 20th to get a consultation.
My question is what should I do with my testosterone dosage until that date? I feel my hct and hmg creeps up too fast due to apnea.
Also phyisque update 180 lbs - I started test at 180 lbs… My body completely recomped losing fat and gaining muscle
This was 180 lbs starting 3 months ago
I would reduce to 80mg per week. Will get you to around 600 to 700 ng/dl on average which is average for your age group and significantly higher than pre TRT.
I’ll most likely do that temporarily until I get apnea squared away
Question;
How does trt affect the Hpa?(not to be confused with hpta)
I am now thinking it has to be physiological, I am 100% mentally calm and it feels like my body is just dumping adrenaline on me. My heart rate sky rockets for no reason, it doesnt bother or scare me, it just is and is uncomfortable. Also very tense and irritable and antsy for noo reason. I’ve even upped my meds and am just mentally zen and observing my body.
I’ve researched in how trt can disrupt the hpa and stop the negative feedback loop in the adrenals.
Pitutiary sends acth → asks for cortisol → trt smashes cortisol → body sends message of lack of cortisol to adrenaline ratio → brain assumes needs more during stress response → sends more acth → which sends more adren → repeat
Anyone know how to fix and raise cortisol? Its not adrenal fatigue, its adrenal insufficiency.
Will get both tested soon
Really late replying (28 days) after @enackers tagged me in your thread here, sorry. What’s your current protocol? Are you still experience hyper vigilance and panic attacks?
100mg per week, and yep still hyper vigilant, irritable 24/7. Mentally I’m calm, but the way things feel is irritating
Gotcha, if you haven’t yet, try the cream. If you look through my old threads I felt like a mess with the injections. 24/7 jumping out of my skin, jittery, panic attacks, racing thoughts, insomnia, etc. The scrotal application of the cream changed everything. I hesitated for months to try it, glad I finally did.
Some guys simply don’t react well to injections. Reactions like yours are not uncommon.
Further reduce your dose to 80 per week. Evaluate in 2 to 3 weeks. I think you are still overdosed taking into consideration the anxiety disorder.
I need to know why though, what process in the brain is causing this? I’m very data driven. What does testosterone affect that causes this?
Gaba? Serotonin? Amygdala? Hypothalamus etc?
There must be an explanation. I am 100% MENTALLY calm, yet physically I’m on edge and feel like I’m going to explode 24/7, yet mentally I’m not mad, sad or anything at all, i am also very paranoid, I basically feel like what everyone says tren sides are. My thoughts arent feeding these feelings, I just feel them and don’t even react yet they intensify. I’ve tried propanolol to see if its an adrenaline think, nope, I’m on an ssri but that doesn’t override it, I’ve tried gabapentin to see if its gaba, but that doesnt seem to effect it. Benzos somewhat dull everything, but they always do.
At this point its anger and irritability, yet I am calm but for some reason just feel like im always on edge about to lose control and explode and it scares me and makes me panic, almost becomes a cycle. I am a very calm person off testosterone, never anger, very passive, if I ever show anger its irratibility passive aggression.
Idk if its dht sensitivity or what. But it makes no sense on this low of a dosage, because it makes me almost reach my natural levels. I am on defys pharma test.
I’m on a mission to figure this out, my ocd tendancies dont allow me to give up. Not unless theres a clear cut explanation as to why this happens.
You are screwing with something that is most likely not the cause of your problems. You are literally lowering your dose to decrease these issues while others increase to normal dose.
This 600-800 is nonsense. Today we know that men and woman have 30-40% less hormones than they did many decades past. It’s a epedemic. Our body needs what it needs.
I would stop blaming T for all these issues and man up and give the body what it needs. I would focus on my mental aspect. I would use the cream and at night I would take shit to help
Me sleep. GABA THEANINE MELATONIN MAGNESIUM GLYCINATE.
The majority of folks who complain of anxiety on TRT have had anxiety before TRT. TRT simply makes you livelier. You just haven’t learned to manage your anxiety.
Pray meditate accept life for what it is. It might not be chemical. It might be your OCD brain mind fucking itself every 5 mins. You make a change and expect it to help and it never does.
To me that’s insanity. Doing the same thing over and over again expecting different results.
I get anxiety. It’s life. Life is hard. I manage. I don’t go change my dose because T causes my anxiety. I review my acceptance of how my life is going at the moment and learnt I stay positive and tell my brain to PLEASE stfu” . Because it will kill me otherwise.
This is the traditional approach of medical care in the USA. Mom died and you are depressed? Divorced recently? Here take an SSRI.
Oh no you have anxiety. Here is some Xanax.
It’s not like people take this shit temporarily and are better after a three month run of it . It is not therapy. It’s suppression of symptoms. If one does not deal with the inability to accept the fact that people die and they got divorced, they will continue having these issues.
There are folks who have chemical imbalances and they need medicine. But they manage and many learn how to live life to it’s optimal without Relying on medicine and quick fixes (alcohol drugs food gambling sex).
I hope this makes sense because you are being led to insanity by the folks who constantly affirm what your brain is saying.
Just get off the TRT and stop complaining if it’s really the T fault. If you don’t want to, then learn to live with it.
Sometimes we don’t get to know why. Sometimes we just have to make changes and allow our bodies to dictate how it’s going utilize the chemicals we put in it. There are a lot of biological effects that we know for a fact these hormones have on us. On the other hand, everyone is biochemically unique and some of us (a lot on this website) are wildcards.
I have literal diagnosed OCD, when I felt like you I was out of control with the research, among other horrific outcomes of that disorder. It never got me anywhere, I spun my wheels until they burned. Just go look at my threads, every participant had a theory, I’m sure someone was right about the minutiae of what’s going on biochemically. However, it didn’t matter, we can’t directly influence those effects. The downstream effects of these “master” hormones are seemingly infinite and new ones are being discovered every day.
I can tell you my OCD was practically non-existent after only a couple months on the cream. All you can do is try new approaches and see what eventually sticks.
GABA THEANINE MELATONIN MAGNESIUM GLYCINATE.
Taken all of that for years, nothing is new to me. I don’t expect trt to be a cure for my anxiety anymore, I just want TRT to work for TRT benefits, Energy, libido, sexual function and muscle gain. However for some reason it poses many side effects for me and I would like to know why, what makes me so different? You all discuss the science and pros/cons to high e2, low e2, high t low t, and all of the other hormones in balance, well mine are in balance and were in balance pre trt and on trt, there is almost no difference to my pre trt and my current protocol yet I feel this way on pharma grade, even with dif oils, I tried cream today and that actual amplified how I feel. I’m totally chill and calm about it but just observing whats going on.
I just wanna find an answer, you guys seem to have it all figured out so I don’t see what’s lacking here. I love the way trt makes me feel, the only thing that sucks is the anxiety/irritability/aggression(or whatever this feeling is, its like a blind uncontrollable unprovoked anger @ nothing, I’ll be totally chill and feel like I wanna hit something for no reason).

