[quote]KSman wrote:
There are some dopamine tests, but I do not think that they would be very useful. The best diagnostic is a trial of a dopergenic drug and your own observations. Cheaper than labs and very specific to you.[/quote]
sounds good, I will get on this,I kept the meds you described,thanks again
Ksman…with my long history of symptoms,we have talked about taking EPHEDRA,stimulints etc…I was doing
some research and long term use of methylprednisolone can and does cause CUSHING DIEASE,which blows out ANDRENALS and we not what that can do,I have been getting these injections for years,and go every 3 weeks,you
ever hear anything about that,probs with my adrenals which we have talked in the past,so would make me feel shitty…thanks alot,to you,and anyone with any info
“Methylprednisolone has serious side effects if taken long-term, including weight gain, glaucoma, The most serious side effect occurs after the adrenal glands cease natural production of cortisone, which methylprednisolone will replace”.
When one takes cortisone type drugs, natural production of cortisol is reduced or shut down. There are many other related negative effects. If you stop the cortisone suddenly, death can result.
With cortisone type drugs one can have muscle wasting and arms/legs can become thin while the body becomes fat. One can see this body shape change at a glance. People taking these corticosteroids should be given testosterone to prevent muscle wasting. In your case, you are doing that. If testosterone is not used, there can be severe bone loss for some and that can be seen as a loss of height as the spinal column becomes compressed and compacted.
Why did you ever start methylprednisolone and do you still have those same symptoms. Injecting every 3 weeks is a hammer. You could try to get off of the methylprednisolone by tapering onto daily oral drugs that probably need to be taken more than once a day. Then you can make other changes that are adrenal supportive and try to taper out of the adrenal steroid drugs. You would need to carefully read Wilson’s book. You would need to take DHEA and use small amounts of OTC progesterone cream.
Are your methylprednisolone injections targeted to specific locations. All of these issues and effects are dose related.
Stimulants are hard on the adrenals. That includes caffeine. Many can change their life styles to reduce stresses that create flight or fight adrenal responses. In your case, you need that response to survive your combat sports. You will need to be calm outside of sparing and fighting.
[quote]KSman wrote:
Why did you ever start methylprednisolone and do you still have those same symptoms. Injecting every 3 weeks is a hammer. You could try to get off of the methylprednisolone by tapering onto daily oral drugs that probably need to be taken more than once a day. Then you can make other changes that are adrenal supportive and try to taper out of the adrenal steroid drugs. You would need to carefully read Wilson’s book. You would need to take DHEA and use small amounts of OTC progesterone cream.
Are your methylprednisolone injections targeted to specific locations. All of these issues and effects are dose related.
I got a rib injury,5 years ago,went to 5 dr’s including a pysiatrist(prob spelled wrong)
hes like a super pain doc,MRIS,CT SCANS,EXRAYS,NERV TESTS.ETC…
was going to have the nerve injected with alsohol,as this kills the nerve and all feeling and pain there,but no dr would do it,as to if I broke my rib,i would not feel it,and it would go though my lung…so I found a dr,well respected,big time these parts,started treating the band of muscles over the rib,etc…seems to work, the other dr’s would use MARICAINE,LIDOICAIN,KENALOG,ADRENILIN…Im due for another injection on wednesday…
and he injects along the 5th rib,about 4 spots along the lenght of the rib,not up and down
I always wondered. about long term use,but I know its a hefty bill he charges…
on a good note,I pulled the bait n switch…got a dr to give me adex…showede to my friend dr,and now he gave me adex for as long as i choose…so thank you for that
BUMP Ksman,
hello ksman,Im going to the dr. today we talk about dompine,which you think mine is low from years of stimulints…ive read Zoloft,is the only 1 that will increase DOMPINE ?
,and that most other only increase seritonin ? .today at dr,which do you think I should ask for ? anyone taking these,please feel free to reply…thanks guys…
I have been on zoloft…not fun. Cabergoline or selegiline has worked for me as well as sinemet.
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[quote]KSman wrote:
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[/quote]
Also got my labs back… E2 77 REF- 40.0-115.0 ,and thats on .5 mg 3x a week
free test 17.9- ref 10.8-40.0
think I used the same lab…gonna find old labs…
old labs from DEC say ESTRA was 45 REF (12-41),so must be differnt lab…but either way,its still high at 77, THATS ON .5 3X A WEEK…I dont feel anyworse, might be me,but seems a lil joint probs very min,a quick ache,then gone,but could be just me,I train hard…
thank you very much
[quote]KSman wrote:
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[/quote]
ok so Ill go with WELLBUTRIN 1st…unless you suggest something else…
E2 labs: Please post the exact description of the labs with units pg?ng per ml?dl?. Range seems bogus.
Was that free or total estradiol?
Blood work or saliva?
I do not think that we can compare the two labs at this point.
Found:
“”"
Estrogen, Total, Serum
CPT Code(s): 82672
Specimen Container:
No additive (red-top)
Preferred Specimen:
1.5 mL serum (1 mL minimum)
Transport Temperature:
Refrigerated
Reject Criteria:
Received room temperature
Methodology:
Extraction, Radioimmunoassay
Reference Range:
Total Serum Estrogen pg/mL
Males:
Prepubertal: <40.0
Adults: 40.0 - 115.0"“”
You seem to have total estrogens, not estradiol.
Suggest .75 mg adex 3x/week and get the proper testing done.
Did you tell the doc to test for estradiol or estogens?
[quote]fightu35 wrote:
[quote]KSman wrote:
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[/quote]
Also got my labs back… E2 77 REF- 40.0-115.0 ,and thats on .5 mg 3x a week
free test 17.9- ref 10.8-40.0
think I used the same lab…gonna find old labs…
old labs from DEC say ESTRA was 45 REF (12-41),so must be differnt lab…but either way,its still high at 77, THATS ON .5 3X A WEEK…I dont feel anyworse, might be me,but seems a lil joint probs very min,a quick ache,then gone,but could be just me,I train hard…
thank you very much[/quote]
[quote]KSman wrote:
E2 labs: Please post the exact description of the labs with units pg?ng per ml?dl?. Range seems bogus.
Was that free or total estradiol?
Blood work or saliva?
I do not think that we can compare the two labs at this point.
Found:
“”"
Estrogen, Total, Serum
CPT Code(s): 82672
Specimen Container:
No additive (red-top)
Preferred Specimen:
1.5 mL serum (1 mL minimum)
Transport Temperature:
Refrigerated
Reject Criteria:
Received room temperature
Methodology:
Extraction, Radioimmunoassay
Reference Range:
Total Serum Estrogen pg/mL
Males:
Prepubertal: <40.0
Adults: 40.0 - 115.0"“”
You seem to have total estrogens, not estradiol.
Suggest .75 mg adex 3x/week and get the proper testing done.
Did you tell the doc to test for estradiol or estogens?
[quote]fightu35 wrote:
[quote]KSman wrote:
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[/quote]
Also got my labs back… E2 77 REF- 40.0-115.0 ,and thats on .5 mg 3x a week
free test 17.9- ref 10.8-40.0
think I used the same lab…gonna find old labs…
old labs from DEC say ESTRA was 45 REF (12-41),so must be differnt lab…but either way,its still high at 77, THATS ON .5 3X A WEEK…I dont feel anyworse, might be me,but seems a lil joint probs very min,a quick ache,then gone,but could be just me,I train hard…
thank you very much[/quote]
[/quote]
TOTAL SERUM ESTROGEN
ADULT 40.0-115.0PG/ML
MINE WAS 77.0 THAT WAS A BLOOD TEST…
says ESTROGEN,I seen on the forms the test for ultra sensitive ?
you tell me what to exactly and I can get it done right away…
on the form I seen like 3 tests…thanks again…but either way its high right ?
so do the adjust ? or wait ?..THANK YOU !
I think that someone has there labs mixed up. Challenge someone to backup what they are doing.
[quote]KSman wrote:
I think that someone has there labs mixed up. Challenge someone to backup what they are doing.[/quote]
I hear ya…Ill go Monday for new test…and ask for what test you think is best…
also…how did my free test go to 17.9 ref 10.8-40.0 pg/ml
total was 533
[quote]fightu35 wrote:
also…how did my free test go to 17.9 ref 10.8-40.0 pg/ml
total was 533[/quote]
I do not understand the question. In general, FT increases when TT increases. The ratio of FT:TT can increase if SHBG goes down. Lower E2 can do that. And when T levels are even higher, that also lowers SHBG.
At this point, it looks like you need a higher dose of T.
[quote]KSman wrote:
[quote]fightu35 wrote:
also…how did my free test go to 17.9 ref 10.8-40.0 pg/ml
total was 533[/quote]
I do not understand the question. In general, FT increases when TT increases. The ratio of FT:TT can increase if SHBG goes down. Lower E2 can do that. And when T levels are even higher, that also lowers SHBG.
At this point, it looks like you need a higher dose of T.[/quote]
now I need more higher dose ?,with all due respect,has to be another way to fix this with out just upping TEST… the dose cant just keep going up,he wont do it…so what should
I do, when I had blood drawn,I watched her fill out the paper work on the pc screen,there was like 4 types of ESTROGEN tests…I seen ultra sensitive…and other, what is the exact test I should ask for,will have blood drawn in the am…
Suggest .75 mg adex 3x/week and get the proper testing done.
I have the 1mg tabs…
Get liquid or dissolve tabs in vodka.
[quote]KSman wrote:
Get liquid or dissolve tabs in vodka.[/quote]
my Arimidex is free,so rather not pay for it,but…
dissolve in vodka ? for real ? then what ,how…
going for blood work today…to make sure I get the right test for estrogen,whats the exact name i tell i want…
[quote]KSman wrote:
E2 labs: Please post the exact description of the labs with units pg?ng per ml?dl?. Range seems bogus.
Was that free or total estradiol?
Blood work or saliva?
I do not think that we can compare the two labs at this point.
Found:
“”"
Estrogen, Total, Serum
CPT Code(s): 82672
Specimen Container:
No additive (red-top)
Preferred Specimen:
1.5 mL serum (1 mL minimum)
Transport Temperature:
Refrigerated
Reject Criteria:
Received room temperature
Methodology:
Extraction, Radioimmunoassay
Reference Range:
Total Serum Estrogen pg/mL
Males:
Prepubertal: <40.0
Adults: 40.0 - 115.0"“”
You seem to have total estrogens, not estradiol.
Suggest .75 mg adex 3x/week and get the proper testing done.
Did you tell the doc to test for estradiol or estogens?
[quote]fightu35 wrote:
[quote]KSman wrote:
Zoloft is an SSRI:
You need to refuse any SSRIs. SSRIs have too many side effects.
I do not know what you are reading.
Sertraline is primarily a serotonin reuptake inhibitor (SRI) and a mild dopamine reuptake inhibitor
Bupropion/Wellbutrin is a dopamine and norepinephrine reuptake inhibitor.
It is about twice as potent an inhibitor of dopamine reuptake than of norepinephrine reuptake.
[/quote]
Also got my labs back… E2 77 REF- 40.0-115.0 ,and thats on .5 mg 3x a week
free test 17.9- ref 10.8-40.0
think I used the same lab…gonna find old labs…
old labs from DEC say ESTRA was 45 REF (12-41),so must be differnt lab…but either way,its still high at 77, THATS ON .5 3X A WEEK…I dont feel anyworse, might be me,but seems a lil joint probs very min,a quick ache,then gone,but could be just me,I train hard…
thank you very much[/quote]
[/quote]
OK got my new ESTRADIOL TEST BACK,you was right they tested ESTROGEN last time
its 13 ref ( 12-41) this is on arimidex .5mg 3x a week for 3 weeks,before this my levels where 27-33…now what…