Has anyone done a protocol where they supplement estradiol vs trying to maintain estrogen with ai’s And the right test ratio?
Curious what dosing would be used, roughly to maintain a consistent low level of estrogen.
No right or wrong ratio. Dosing is usually 2-3mg per day.
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Why would you do that as a man? You will always have plenty of estrogen if you take Test unless you suffer from the inability to aromatize.
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Do you personally do this? I was thinking start at 1mg a day and do labs in a few weeks.
If you don’t want to use test you do. And HCG alone does not give me consistency or enough estrogen.
But that would also mean HCG is not generating enough Test as well, since T is precursor to E2 in men. Hence you need to take Test.
Unless you have the aromatization defficiency mentioned earlier.
I have and I know others. I did it for six weeks as an experiment to help with joint pain. I did not get blood tests while taking it though. May try it again as it helped and I had no negative effects.
Why do you think you need it?
I’m tired of the marginal benefit of test and too much or too little estrogen. I’m there are plenty of inexperienced opinions on this but my plan is to run boldenone for numerous reasons, mainly no side effects what so ever for me. Better joint health, lower inflammation, better sex drive (with adequate estrogen) But I don’t aromatize enough to maintain a normal estrogen level. Dose dependent of course, but I don’t want to take gross amounts just to maintain estrogen.
Dependent on your levels starting out, I’d do 1-2mg then. I’ve known of some going as high as 8mg, but that was with a lot of testosterone.
I’ll try it. I appreciate the input. For me I can’t go over 20pg/dL without side effects creeping up
Definitely do not go over 1mg then.
Looking through the more-recent estradiol valerate thread but came across several older posts like yours highpull, regarding EV dosing.
For those that have tried estradiol valerate, or prescribers that sometimes prescribe it, I assume these are 1mg or 2mg tablets?
It appears most/all of the estradiol products out there are injectables, patches, or creams. Having a hard time finding tablets at American pharmacies that are pure EV and not mixed with other hormones.
We use estradiol, compounded, capsules, 1-3mg. We also use cypionate and creams.
Thanks very much!
I think I found some near me, 2mg generic that seems widely available. Will try those before going the compounding route.
I know your male patients on estradiol are a small fraction of your practice but does it seem to be well-tolerated for those who do take it?
Have you seen men in your practice achieve symtpom relief from it?
I think I saw you reference men not typically staying on it long-term. Is this because taking it seems to reset estrogen/serotonin balance or receptor function (or whatever mechanism underlies the low-estrogen symptoms for some men) and staying on it long-term isn’t necessary, or because your Pts tried it and found that it didn’t achieve the intended result?
Yes.
Yes.
My guess is estradiol eventually built up on its own so we could stop supplementing it.
I did, love it, best thing i ever did in my roid-life, it fixed my dead cock which ive had since 2017.
Extreme pumps, zero joint pain, great libido, great erection, good good good
Started mine today. You’ve been my inspiration to try; if I experience half of the positive effects you experienced I’ll be ecstatic. 
Doing 1 mg/day initially for 4 weeks, will see how I feel over next several weeks and get some bloods at that time.
I’m high(er) SHBG (now finally down to mid-40’s after years in the 60’s/70’s). My E2 seems to vasciallate between 20-40 but has settled in around 35 the last year or so. Running 120 mg/week cypionate split into two doses per week. Total T is around 1300.
Started TRT two years ago at 45 YO with clinically normal T (400-900, depending on time of day) but with very high SHBG, so my free T was tanked and I was getting all the low T symptoms.
Sleep, mood, muscle gain, got better at 100 mg/week. Libido mildly better but not great. Erection quality and sensitivity still very poor relative to pre-onset of symptoms at the beginning of 2020.
At that time I’d been intermittent fasting and low carb for a few years and think what kicked me into this hormonal imbalance was some combination of keto and unintentional calorie restriction from the IF causing high cortisol/stress/whatever and my axis got out of whack.
Have run up to 160/week over last couple of years and tried splitting doses vs. one dose, with no signficant difference in sexual side effect relief at any T dosage or frequency. Have supplemented DHEA, Pregnenalone at various dosages with no change in symptoms. Am on daily Cialis and it may help mildly but not substantially. Aside from poor erection quality definitely just don’t feel turned on/sensitive/eager the way I did pre-symptoms, not even close.
The best I’ve felt was back in the fall when, due to high hematocrit, I cut my dose from 150/wk down to 120/wk and stopped DHEA and preg. For a couple of weeks I was getting way more nightime boners and felt more sensitive.
Looking back at my bloods from that time a couple of weeks ago, I noticed my estrogen was the highest its been (although still not high at around 40) and started wondering if feeing good at that time was due to my T levels dropping but E2 maybe lingering at a higher level for a couple of weeks before settling down again. I don’t aromatize much so even at 160/wk TT my E2 doesn’t get out of the 40’s, and with my higher SHBG what E2 I do have gets bound up.
We’ll see if bumping E2 to get more up to that 20:1-type ratio moves the needle. (Or the “needle”, hah!). Would be ecstatic for even moderate improvement in libido, erection quality, and sensitivity.
Have you experienced any sides other than mood (acne, oily skin, tingly nips, etc.)?
Also have you ever gotten bloods post-estradiol supplementation?
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No sides mate, zero!
No bloods yet, ima retard freestyler baby.
I dont even get bloat, like Nothing.
When i upped to 4mg a day i felt nostalgia and shit, so dropped it.
Also the first days on 2mg, also great great nostalgia thinking about the good old days but that dissapeared quickly.
Good luck mate
Notice anything at all after first few doses?
Nada so far, good or bad. I keep imagining stuff but I’m pretty sure it’s psychosomatic. 
Only been 4 doses of 1mg so far though. Planning to give it 4 weeks regardless and do bloods and see how I’m feeling at that time.
Unless I start growing a Sidney Sweeney pair. Then I’m out. 