[quote]progwizard wrote:
I found this article for people interested in piperine interactions of different drugs.
http://www.delano.com/Articles/piperine-multiplies.html [/quote]
Thanks for the info. Good read.
[quote]bluebear wrote:
As much as you seem to be lovng flaming my post, it irritates the hell out of me that the medical profession in general looks down on nutraceuticals as lesser products than a new chemical entity that has been through all 3 trial phases for its marketing authorisation.
The use of clinical claims on food products is now regulated by the European Medicines Agency and each member states legislation, its one reason that certain yoghurt manufacturing companies are spending huge amounts of Euro’s on performing clinical trials to back up their claims on their products.
The supplement industry suffers even more as the general masses of medical professionals who do not do their reading on the background, such is cited on the Biotest product pages.
[/quote]
I have to admit that my curiosity was a tad piqued when I read the article, considering that they are basically admitting to “curing” pain to a certain degree… I know there is linguistics to consider and that is generally how the supplement industry skirts the FDA (Statements like “Boosts the immune system” and “Heart healthy” instead of “Lower your cholesterol” or “Kills bacteria”)
This one just seemed to be riding that fine line a little bit more than there other stuff…
My two bottles arrived today. I’ll start taking it with dinner tonight.
Does this product work like a blood thinner?
For example, is it possible to use it to replace the “A” (Aspirin ) inside the E/C/A stack?
The end result is the most powerful curcumin formulation ever available.
Enter Biotest’s Curcumin 500, the first potent and fully natural pain reliever that’s also good for you.
It’s not like this (Curcumin + Bioperine) hasn’t been done before. Better ways of improving Circumin bioavailability exist.
Is there any Biotest supplements this shouldn’t be stacked with? I see HOT-ROX has Piperine in it already.
Im not entirely familiar with this supp. Would it be suitable as a replacement for a joint supp such as glucosamine, MSM, etc?
If so that would be great.
Can this be used while taking Alpha Male?
[quote]stevewar wrote:
I’m confused, but I am used to Biotest comming up with revolutionary compounds and formulas, which appears not to be the case this time. Adding piperine to curcumin forumlas has been done since 1998. Further, there are many other ways of increasing the bioavailability of curcumin including nano encapsulation and lipidation (neither of which are mentioned in the article.)
finally, there are several 95% pure curcumin formulas with piperine in them avaiable just about anywhere for a similar cost.
So my question is, what did Biotest do that was so revolutionary and hardcore to this formula?[/quote]
Exactly! I’ve been so disappointed with the recent product lineup: Rhodilia Rosea, Alpha-GPC and now this. These are all basic supplements that can already be found from many other companies so why not try and go above and behond and make something great. This place is Testosterone Nation so there should be more products geared at building muscle, I feel like this is Men’s Health or something
[quote]billwise23 wrote:
Does this product work like a blood thinner?
For example, is it possible to use it to replace the “A” (Aspirin ) inside the E/C/A stack?[/quote]
BW23,
Curcumin can decrease platelet aggregation, so it may have blood “thinning” properties. But as with all supps, the effect is dose related. That said, curcumin in no way should be used to replace the aspirin in the ECA stack.
TZ
[quote]redgladiator wrote:
Is there any Biotest supplements this shouldn’t be stacked with? I see HOT-ROX has Piperine in it already.[/quote]
RG,
Stacking supps is always a tricky proposition, and impossible to predict with certainty on an individual basis, so stick closely to the recommended use guidelines for all Biotest supps. (Not a cop-out, just my honest opinion.)
TZ
[quote]nick1990 wrote:
Im not entirely familiar with this supp. Would it be suitable as a replacement for a joint supp such as glucosamine, MSM, etc?
If so that would be great.[/quote]
N1990,
Not a replacement per se, but an add-on to enhance joint health. For example, use of C500 may allow you to reduce your dosages of glucosamine, MSM, etc and still maintain a desired (or even an enhanced) effect.
TZ
[quote]PecDec wrote:
Can this be used while taking Alpha Male?[/quote]
PD,
Again with the caveat that I am not a MD and my opinion is not a substitute for medical advice…I do not see why Alpha Male and C500 couldn’t be used together.
TZ
Here is my initial anecdotal feedback:
Just coming off of a 2 week deload phase due to joint pain and general fatigue, so I was feeling pretty fresh yesterday…though weak due to the reduced workload.
After Warmup
5 Cycles of
Clean & Press 185lbs (5 Reps)
Supersetted with Chins to Failure
Supersetted with Pistols - 8 Reps each leg
90 Seconds Rest
Deads (first time in a long time)
315 x 3
405 x 2
455 x 2
Triple Drop Set Hip Sled for 3 Cycles (squats are a can’t do at the moment due to the ROM for my knees)
3 Sets of Negative Only Glute Ham x 5 Reps
Woke up this AM and was quite sore across the traps, hams are very painful, quads sore, but not too bad - and my knees felt like they usually do after a hard leg session - like my cartilage has been replaced by shards of glass, acutely painful (due for a double scope this summer)to the point that a body weight squat was quite painful up until I ingested the supplement.
Upon waking, had some blueberries and Grow! Shake, along with my usual coffee.
90 Minutes Later - took two caps. About 45 minutes later I noticed:
1 - Slightly ‘warm’ feeling, not like HOT-ROX, but milder…it felt good.
2 - My joints felt (including elbows) like they were ‘lubricated’ to a greater extent. Based upon the bodyweight squat comparison, I’d say that the pain was reduced by about 50%, which in my mind is outstanding due to the prior pain index.
3 - Soreness in my traps, reduced by approximately 75% - Ham Soreness about 75% reduced, and they HURT beforehand.
4 - A general feeling of well being…interesting, obviously highly subjective, and could be attributed to the reduced inflammation/pain?
A key differentiator, is that before I took it, the last thing that I wanted to do was think about hitting it again today. After my dose, I feel much better, and will absolutely do some HIIT Cycling in the late afternoon.
In my mind, this is a key benefit for any athlete - especially a competitive athlete…the ability to recovery faster, (reduction of inflammation) which faster return to functionality in the gym/field, which is further enhanced by the removal of the ‘mental’ block that pain/inflammation can sometimes induce.
I think that majority of people really don’t understand the signficant impact that inflammation has on athletes, specifically from a recovery perspective. Just a thought.
So there it is - my unscientific/highly subjective feedback - Based upon the mix of acute pain, and DOMS related soreness, I’d give this supplement a 4 Star Rating based upon my initial experience, and when combined with the other health benefits, I think its a no brainer at this price point.
now if one were to use this only for basically joint health, reduced soreness and less inflammation would he just take it twice a day daily for as long as he likes?
[quote]Beej1989 wrote:
stevewar wrote:
I’m confused, but I am used to Biotest comming up with revolutionary compounds and formulas, which appears not to be the case this time. Adding piperine to curcumin forumlas has been done since 1998. Further, there are many other ways of increasing the bioavailability of curcumin including nano encapsulation and lipidation (neither of which are mentioned in the article.)
finally, there are several 95% pure curcumin formulas with piperine in them avaiable just about anywhere for a similar cost.
So my question is, what did Biotest do that was so revolutionary and hardcore to this formula?
Exactly! I’ve been so disappointed with the recent product lineup: Rhodilia Rosea, Alpha-GPC and now this. These are all basic supplements that can already be found from many other companies so why not try and go above and behond and make something great. This place is Testosterone Nation so there should be more products geared at building muscle, I feel like this is Men’s Health or something[/quote]
In reponse to this, you guys make solid arguments but I like the fact that I can get almost everything I need at T-Nation. I’m not saying I buy evrything here. But since they’ve expanded the repertoire, things have got a lot more convenient then they used to be when I had to shop online, shop in person, get a hook-up, etc.
similar, sometimes better cost, free shipping, and I can get direct feedback from the company and others on what works and what doesn’t.
Rosea has been a life saver for my changes in work schedule, and if the curcumin works out the way I think it will, once again they save me some extra time and cost. Not to mention I can finally ditch the Advil. Since as I said in earlier posts my knowledge in this field is limited.
And since I am now beginning to sound like a Biotest whore I will end my post.
My question is more in terms of treatment rather than prevention of cancer.
Honestly I am at a point of desperation. My mother has a severe case of cancer (Merkel Cell Carcinoma) and is in the middle of her 4th out of 6 consecutive rounds of chemo. She has had surgery, radiation and now the chemo. Surgery and radiation did very little to halt the spread, while the chemo has seemed to have halted the spread, although it is still not shrinking the tumors. My fear is that once the chemo inevitably stops the tumors will start growing again.
This cancer is quite rare and her doctor works with multiple hospitals throughout the country in discussing my mother’s case. The one area they all seem lacking is of course supplementation.
I have convinced my mom to give this product a try. Maybe it does nothing, but to me it is worth a try at this point
I am thinking 3 caps a day? I also tried to get her to try Superfood but to no avail.
Grasping at straws here…any advice (understood this is not medical advice) would be appreciated.
[quote]Tim Ziegenfuss wrote:
Slay the Dragon wrote:
I noticed the main types of pain mentioned were related to inflamation, how would this supplement aid someone with a herniated disk? Would there be a noticeable difference?
STD,
Curcumin 500 is often used as a substitute for NSAIDs, but it depends on the nature of the disk herniation. One thing is for sure, it can’t hurt.
TZ[/quote]
It’s a moderatley herniated disk between L5-S1. Whats your opinion?
[quote]Slay the Dragon wrote:
Tim Ziegenfuss wrote:
Slay the Dragon wrote:
I noticed the main types of pain mentioned were related to inflamation, how would this supplement aid someone with a herniated disk? Would there be a noticeable difference?
STD,
Curcumin 500 is often used as a substitute for NSAIDs, but it depends on the nature of the disk herniation. One thing is for sure, it can’t hurt.
TZ
It’s a moderatley herniated disk between L5-S1. Whats your opinion?
[/quote]
STD,
I see your from NJ. Make an appt with Dr. Hector Lopez from the Performance Spine & Sports Medicine. Tell him I recommended you. 
http://www.njspineandsports.com/index.html
TZ
[quote]rmnelson75 wrote:
My question is more in terms of treatment rather than prevention of cancer.
Honestly I am at a point of desperation. My mother has a severe case of cancer (Merkel Cell Carcinoma) and is in the middle of her 4th out of 6 consecutive rounds of chemo. She has had surgery, radiation and now the chemo. Surgery and radiation did very little to halt the spread, while the chemo has seemed to have halted the spread, although it is still not shrinking the tumors. My fear is that once the chemo inevitably stops the tumors will start growing again.
This cancer is quite rare and her doctor works with multiple hospitals throughout the country in discussing my mother’s case. The one area they all seem lacking is of course supplementation.
I have convinced my mom to give this product a try. Maybe it does nothing, but to me it is worth a try at this point
I am thinking 3 caps a day? I also tried to get her to try Superfood but to no avail.
Grasping at straws here…any advice (understood this is not medical advice) would be appreciated.[/quote]
RMN75,
I’d recommend going to lef.org and reading up on their recommendations for cancer treatment. Lots of good ideas there.
Best of luck.
TZ