Best Way to Dose Acetyl-L-Carnitine?

What do you guys think for boosting androgen receptors. How about 1 gram at night and 1 gram in the morning?

What nobody at T-Nation has an opinion they feel like sharing?

Sorry, I’ve never used Acetyl-L-Carnitine or any product that contained it so I can’t comment on it. I do know its in ReceptorMax and is found here at the store. Maybe read more up on ReceptorMax or the dosage of Carnitine in ReceptorMax for a better understanding.

i use it 2g in every shake until about 3/4pm cuz i cant sleep if i take it after that…

I think i have become tolerent to it thou.

Scott

i use it…

notice nothing after the first 2 weeks

2g in every shake.

[quote]elusive wrote:
Sorry, I’ve never used Acetyl-L-Carnitine or any product that contained it so I can’t comment on it. I do know its in ReceptorMax and is found here at the store. Maybe read more up on ReceptorMax or the dosage of Carnitine in ReceptorMax for a better understanding.[/quote]

x2.
I was going to take just ALC, but it was going to be like $25, for another $20 you can get all the ingredients in ReceptorMax

I started taking it recently, I get it cheap so I thought I’d give it a try.

First thing I noticed was how potent it smells when you open the container, like vinegar powder I almost got high off the fumes :slight_smile:

I take 3 grams with a glass of water each day I workout (5 days),pre workout and I’ve noticed an increase in energy during and post workouts.

I’ve been taking it for about 2 weeks now.

There is a danger with ALC. Take alpha lipoic acid with it or you may be reducing your lifespan; possibly dropping years off your life. The reason has to do with the mitochondria in the body’s cells.

It is the same principle behind caloric restriction extending lifespan and exercise increasing lifespan. Basically, the mitochondria are the cells’ power plants. They use electricity to burn fuel with oxygen. If you have too much energy with nowhere to go, the sparks escape and damage your cells and DNA. Over a lifetime the mitochondria run down, the cells and then the body run down, and you get all the degenerative diseases of age.

Alpha lipoic acid is one of the few antioxidants that can enter into the mitochondria and clean that mess up.

[quote]jehovasfitness wrote:
elusive wrote:
Sorry, I’ve never used Acetyl-L-Carnitine or any product that contained it so I can’t comment on it. I do know its in ReceptorMax and is found here at the store. Maybe read more up on ReceptorMax or the dosage of Carnitine in ReceptorMax for a better understanding.

x2.
I was going to take just ALC, but it was going to be like $25, for another $20 you can get all the ingredients in ReceptorMax[/quote]

That’s not fair comment in my opinion. You have more ALC to play around with if you were to buy the powder straight.

Plus, Biotest doesn’t release the amount of each ingredient in R-Max so you don’t know if you’re getting enough of each ingredient for YOUR body to make a difference.

I did not notice much from ALC taking 3g each morning on an empty stomach (per an old article on here, I think it was Poliquin). I’ve heard good things with PLCAR so I’m willing to experiment once with that.

[quote]bushidobadboy wrote:
For me personally, ALCAR is unuseable. It makes me increadibly sleepy. Like falling asleep behind the wheel sleepy. Tired irritated eyes and no motivation to do anything but snooze on the couch.

Strange but true. I know of at least one other person who also has this sort of paradoxical reaction.

BBB[/quote]

I’ve been using 1 gram in the morning with my test boosting stack for the last 6 weeks. I think it’s helping a bit. Stacks going great. Mine doesn’t smell bad though so The poster above me may have a bad batch.

[quote]valiant knight wrote:
If you have too much energy with nowhere to go, the sparks escape and damage your cells and DNA. [/quote]

This made me laugh.

I use 1.5g in the morning and pre-workout (or late afternoon if not working out). It gives a bit of a pick me up.

is Acetyl-L-Carnitine same as L-Carnitine??

Acetyl-L-Carnitine has no demonstrated effect on androgen receptors.

The study was performed with L-Tartrate-L-Carnitine.

Volek, Jeff S., Kraemer, Wiliam J., et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physio Endocrinol Metab 282: E474-E482, 2002.

Biotest, however, put acetyl-L-carnitine in ReceptorMax. I do not know why.

I stopped using ReceptorMax when I learned of this fact and lost some respect for Biotest, though I still love their other products.

[quote]Brant_Drake wrote:
valiant knight wrote:
If you have too much energy with nowhere to go, the sparks escape and damage your cells and DNA.

This made me laugh. [/quote]

:wink: I copied verbatim from a time I had to think of a way to convey to a younger audience just what it meant.

[quote]valiant knight wrote:
Brant_Drake wrote:
valiant knight wrote:
If you have too much energy with nowhere to go, the sparks escape and damage your cells and DNA.

This made me laugh.

:wink: I copied verbatim from a time I had to think of a way to convey to a younger audience just what it meant. [/quote]

Are you a professor or something?

[quote]absolute3 wrote:
Acetyl-L-Carnitine has no demonstrated effect on androgen receptors.

The study was performed with L-Tartrate-L-Carnitine.

Volek, Jeff S., Kraemer, Wiliam J., et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physio Endocrinol Metab 282: E474-E482, 2002.

Biotest, however, put acetyl-L-carnitine in ReceptorMax. I do not know why.

I stopped using ReceptorMax when I learned of this fact and lost some respect for Biotest, though I still love their other products.[/quote]

That seems a little quick to sit in judgment and condemn.

First, do you think in the bloodstream L-tartrate-L-carnitine yields a different form of carnitine than L-carnitine?

It doesn’t. The tartrate is a counterion; together with carnitine it forms a salt, which ions go their separate ways in solution.

Why did Kraemer et al use this form? If I recall correctly one of them was asked and the answer was the sole reason was not wanting to have issues with bulk powder changing properties over time, which is an issue with carnitine powder.

So now we are down to only acetyl-L-carnitine vs carnitine.

I was not involved in the decision but doubt that it was in error.

First, there is a high degree of interconversion between the forms. In other words, ALC yields some L-carnitine in large amounts – the L-carnitine seems to be the active species actually – and L-carnitine yields some ALC.

ALC has higher bioavailability. So it can be a better way of delivering carnitine.

It is highly unlikely that ALC does not do what L-Tartrate-L-Carnitine does in the regards in question. (There are no other known regards where carnitine does something ALC does not.)

I doubt the reason was being cheaper. ALC is not cheaper than L-carnitine, and adding a tartrate salt actually decreases cost per kilo, and would increase cost per amount of actual L-carnitine only very slightly.

[quote]absolute3 wrote:
Acetyl-L-Carnitine has no demonstrated effect on androgen receptors.

The study was performed with L-Tartrate-L-Carnitine.

Volek, Jeff S., Kraemer, Wiliam J., et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physio Endocrinol Metab 282: E474-E482, 2002.

Biotest, however, put acetyl-L-carnitine in ReceptorMax. I do not know why.

I stopped using ReceptorMax when I learned of this fact and lost some respect for Biotest, though I still love their other products.[/quote]

That seems a little quick to sit in judgment and condemn.

First, in the bloodstream does L-tartrate-L-carnitine yields a different form of carnitine than L-carnitine? If one thought so, then one might conclude, as you did, that the study has no relevance.

But it doesn’t. The tartrate is a counterion; together with carnitine it forms a salt, which ions go their separate ways in solution.

Why did Kraemer et al use this form? If I recall correctly one of them was asked and the answer was the sole reason was not wanting to have issues with bulk powder changing properties over time, which is an issue with L-carnitine powder.

So now we are down to only acetyl-L-carnitine vs carnitine.

I was not involved in the decision but doubt that it was in error.

First, there is a high degree of interconversion between the forms. In other words, ALC yields some L-carnitine in large amounts – the L-carnitine seems to be the active species actually – and L-carnitine yields some ALC.

ALC has higher bioavailability. So it can be a better way of delivering carnitine.

It is highly unlikely that ALC does not do what L-Tartrate-L-Carnitine does in the regards in question. (There are no other known regards where carnitine does something ALC does not.)

I doubt the reason was being cheaper. ALC is not cheaper than L-carnitine, and adding a tartrate salt actually decreases cost per kilo, and would increase cost per amount of actual L-carnitine only very slightly.

Anyway, with regard to the original question, I don’t know the amount of ALC in Receptormax. However the dosing in the Kraemer study was amounts having 1 g of L-carnitine content (the remainder being tartrate content, which is not an active) at breakfast and again at lunch, for a total of 2 g/day.

Myself, I had thought 3 g/day of L-carnitine or ALC a reasonable minimum if using it, just as a personal value with no research behind it, but I certainly never demonstrated that there was no or no substantial benefit with less. It may also be that the 2x/day dosing is much more efficient than the 1x/day dosing I was employing, and perhaps 2 g total per day is as or more effective than 3 g/day the way I was doing it.

[quote]bushidobadboy wrote:
For me personally, ALCAR is unuseable. It makes me increadibly sleepy. Like falling asleep behind the wheel sleepy. Tired irritated eyes and no motivation to do anything but snooze on the couch.

Strange but true. I know of at least one other person who also has this sort of paradoxical reaction.

BBB[/quote]

myself,my mother and my 25 year old brother all have this same effect.

we all complain of a “brain fog” type weird feeling while taking it.