Your Metformin Use

It all comes down to what is effective for each individual. Our bodies can process grains just as well as meat as long as all systems are working properly. It’s all dependent upon which systems in the body are optimal and which ones are lacking as to which dietary options will work best for an individual.

If you have gall bladder issues, you might want steer clear of red meats. If you have type 2 diabetes, then sugars are a thing of the past without medication. If you are borderline, then that’s where things get nit picky. Too little of one food will reverse the effects of one condition, but potentially train the body to create another condition, and vice versa. Moderation and constant fine tuning is my motto.

PhysioLojik was a HUGE advocate for metformin. I have diabetes in my family so based on his recommendation, I started taking it. I think it makes me less insulin resistant. Helps with my blood sugar too.

I love that avatar. I used to use it on a different forum.

@hardartery :joy:

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My wife has been given metformin before our next ivf cycle 500mg 3 times a day, (very complicated reason why) but she had very bad nausea when up to 1000mg. Been switched to slow release which seem better at the minute.

Do you guys have any issues with nausea? Any ideas to limit it? It’s really important that she takes these for 3 months at 1500mg a day and at the minute that looks unlikely with the sickness.

That’s a common side effect according to he interwebs. Haven’t tried it yet myself though.

Make sure take with meal. I take 1000 mg xr at once with dinner and so far so good

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Tell her to make sure she takes it split-dose. Half with breakfast and half with the last meal of the day. Also the doses should be taken with the first bite of food. I read a lot about this before I started and this is how I’ve done it. Haven’t had a single issue with nausea.

Edit to add …

If she still has issues with 750mg a dose, then try splitting it further into 500mg breakfast, lunch, and dinner.

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I never had nausea, but when I first started taking it had a week or so of really bad diarrhea.

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Im interesting case for example.
My insulin sensitivity seems to be shitty and also my glucose fasted at morning is a bit high:

Glucose S 5.19 mmol/l 2.80 - 6.10 HK

Seems Im predisposed to both kind of diabetes so eating carbs especially fast seems like a no-no for me. And all my life so far I’ve eaten a lot of carbs because I was feeling high after eating them and well satisfied in terms of hunger. But after a few hours Im starving to eat more, and more…

I am of the same mind…I think eating low carb or keto or paleo only avoids the problem which remains. Sure, you’ll have improved glucose readings, but that’s only because there’s not much glucose in the system. It’s not because sensitivity has been re-established.

I have a friend who is of the mind that insulin sensitivity is an autoimmune problem brought on by a bad omega 6/3 ratios. He went from full blown type 2 diabetic to no diabetes and now eats tons of carbs and fruits. He says his body soaks up sugars like crazy now. Obviously this is only an example of one, and it could be called bro-science, but in his case, he actually is a scientist, and a high level one at that.

I was just wondering if anyone else has heard the autoimmune angle from anyone anywhere out there? Because like I said, I certainly don’t buy the whole, “reducing carbs increases insulin sensitivity” angle…although I think it’s a great idea to avoid table sugar because of the fructose which goes only to the liver, and a fatty liver has been shown to contribute to insulin resistance I believe…

A shitty diet and less than ideal numbers doesn’t necessarily make you genetically predisposed to anything. Does diabetes run in your family?

No, but my brother has slight insulin resistance and takes metformin so seems I’m predisposed from my blood levels

No your blood levels do not predispose you. It just serves as a warning that your diet is putting you at risk. ANY normal, healthy person could eat poorly for 6 months and start seeing elevated FBG. It doesn’t make them predisposed, it just makes them the victim of their own poor choices.

Someone who is predisposed can eat the cleanest diet possible and do everything right, but is still at risk no matter what they do. Poor diet choices for these people are even more detrimental.

I was stupid growing up. I was at risk genetically, AND I ate a shitty diet most of my life. I shot my own self in the foot so now, I have to be very careful diet wise, and utilize the help of modern medicine to keep things in check.

New A1C today. Different lab. 5.2 this time. So, swing from 7.5 to 5.2 in three days. Guess I’m looking for lab number three.

Been using 2 x 1000mg a day for insulin resistance. No side effects except it dropped my B12 and folic acid to almost non - existent. (B12 under 100). Currently on Hydroxocobalamin 1000mcg EOD. After the loading phase I will keep injecting once a month. It is worth checking your B12 and folic acid when you are on Metformin. Other than that dropped from 30% bf to almost 20% in less than 6 months.

Lets resurrect the subject: I started using again this week the metformin XR (Glucofage I believe is the brand). It is 1000mg so I split it into two, I know it shouldn’t be split but I dont care because I can feel it acting long time.
So I started with a half of 500mg evening time. First time I took it on the next day felt terrible - very weak, forgetting things, cannot focus and when I had my lunch my energy completely crashed. I needed to take some sugar and additional vitamin d to resurrect myself(literally).

I took it again at evening and the next day was much better.

Also today I feel sleepy, but nothing dramatic. Hope all shitty sides disappear so I will be able to stay on this drug.

I’ve been fascinated looking at metformin. However, lately I read that it increases SHBG and so decreases free T. Has anyone heard of this?

I started 1000 mg xr in June. Lost 5 pounds. I am not even prediabetes and even have a fasting glucose under 80.
Am hoping it reduces my belly visceral fat soon.

I use to get higher numbers on 88 mg test a week. I believe it was the metformin that lowered my total and free t To low normal. I increased my injections to 104 mg gradually to compensate.

Will retake labs soon. Full labs including insulin , dhea, thyroid, b12-folate,lipids etc

I will post on my thread

You still taking metformin? What’s the plan