Maybe hours. Days is a bit of a stretch, IMO.
Hang around a job site. They have their own laugh that you can spot once you know it.
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Are you positive they are not smoking on the way to work, or on break? I am pretty skeptical that any noticeable impact from THC would be around days later.
Maybe you perceive things better than I do.
The guys who smoke heavy on the weekends definitely are like this, the guys who burn daily but not excessively get it after a few years. Occasional users don’t.
Are you sure that they aren’t high when you notice it? I have never noticed consistent weird laughs from notable people like: Snoop, Willie, Dave Chappelle…
You can never be 100% certain of anything, not even if you ask directly. It is something you see when you’re around them, mostly when they are relaxed or just doing things without regard for who is watching. If they go completely off for a while, like a few months, it goes away.
Interesting I am not saying you are wrong, just that I haven’t ever experienced anything like that.
Not entirely true, the recreational window for MDMA can be as little as 40mg and as high as say 175mg… that’s a fairly wide therapeutic window… and many do take more, especially at festivals here when exposed to police/sniffer dogs (they down everything they have)
The notion of hyperthermia is also a risk with amphetamine/methamphetamine. Some may disagree with me but it is of my opinion that the risk for these adverse effects, providing you’re actually getting mdma and dosing reasonably (I’ve never used MDMA btw but I’ve seen hundreds of kids use it) the risk for hyperthermia is rather low.
I’d assume the ruptured vessels occur as consequence of a hypertensive crisis, adequate hydration can go a long way in relation to mitigating harm here. I will quote what neuropsychopharmacologist David Nutt said, who said the risk of death from taking mdma is estimated to be less than that of partaking in horseback riding.
Biggest concern with MDMA is long term cardiac and neuropsychiatric effects from prolonged usage
This is entirely true, however most individuals within MY demographic strictly speaking don’t tend to drink like this. The notion other compounds can’t be used in a similar manner isn’t true either. Whilst I don’t condone it… and I actually think it’s retarded… microdosing certain compounds (including MDMA) is gaining traction (particularly psychedelics), I think it’s arupid as we have no literature to even stipulate as to what the long term effect may be.
As for cannabis… yes, residual impairment in terms of cognitive functioning may persist for up to 36 hours post doob, I suppose it’s dose dependent though, I could take a singular drag out of a joint and be 100% fine as viewed by me and everyone around me
It’s not “okay” to use drugs, it’s not “okay” to get drunk… but as to quote the punisher guy on this forum people tend to make not okay decisions, and that’s alright, it’s on them… so long as they’re fully potentially aware of what they’re getting themselves into
Not really, residual cognitive impairment may persist for a few days, and after chronic heavy use deleterious effects on memory may persist for a month, if not more (perhaps irreversible, literature is conflicting)
There’s certainly a demeanor certain people have when they smoke TOOOONNNNS of pot, they tend to be very chill, nice people
They are usually depressed
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This is unrelated to the debate at hand but I wanted to ask and see if you knew, is there some reasonable explanation for why someone would metabolize THC/CBD when smoked far quicker than when ingested? In a trip to Amsterdam, my mates would split a joint whilst I’d have to be set up with my own to even get — and maintain – a high while edibles consistently delivered a high.
I see people talking about addiction…
Careful here, because the mechanisms of addiction haven’t been completely ironed out. There are studies that show some people will be addicted to anything, while others can consume pounds of cocaine and never be addicted. I have personally done a fair share of drugs myself and i have never been addicted to anything.
Studies on rats show a very different picture about something like cocaine addiction. Rats (or i guess it was mice, whatever same shit) that had support systems such as other mice to mingle with, wheels to run on, and things to do were less likely to binge on addictive substances like drugs. Yeah, so take that for what you will but we can see that we do not know how all this works just yet.
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Few variables at hand here, we have genetics (individualistic metabolism / elimination of the drug), threshold for intoxicating effects etc. what you use with the joint, strain at hand etc
So firstly, tobacco according to literature appears to increase the absorption rate of THC, so gram for gram you get more THC out of each joint, same philosophy is associated with booze (can link literature if you want)… given that many in Europe and Aus tend to mix cannabis and tobacco together (old habits/ cultural traditions die hard… truth is tobacco is meant to be mixed with hashish, not weed, as pure resin doesn’t burn adequately… or you can mix hashish and cannabis, however this isn’t particularly feasible unless you have a high tolerance as it’ll probably send you off into the stratosphere. Do you’re friends mix with wacky tobaccy/ drink with fat doinks whilst you don’t?
The mechanisms of elimination regarding cannabis isn’t entirely understood, as the current scheduling of the substance dramatically impedes the ability for one to conduct clinical trials/studies. It is known however that blood/salival concentrations of THC is an incredibly inaccurate way of gauging intoxication, unlike alcohol
I don’t reccomend mixing tobacco with cannabis, as tobacco is a highly addictive substance with the potential to induce deleterious effects long term (hell, mild, yet measurable morphological adaptations have been noted in the coronary arteries teenagers who smoke OCCASIONALLY!!!)… the same has actually been noted with junk food, quite a few kids have fatty streaks visibly present, and this is quite concerning as highly atherosclerosis shouldn’t be present when one is 14-16… mango contains myrecene (terpene) which may potentiate certain aspects of cannabis
Edibles are metabolised entraheparically (two peaks), also metabolized to a more potent form of THC (11 hydroxy THC vs 9 delta THC), many can’t handle edibles as 11-hydroxy counterpart is far more psychedelic/ intoxicating in nature. Hence why anyone who says to me (in person) “hey unreal24278 I want to try weed, what do you think of weed… also I don’t smoke so I wanna eat a brownie, my friend florpdoopity can get me one”… I typically say something along the lines of “I don’t think it’s a good idea, as recreational drug use never is… but I do it too, it’s an individualistic decision to make. If you want to try cannabis know edibles are far more potent and can be quite overwhelming for many, if you can’t smoke try one or two bites, wait 2-3 hours, you can always have more… but you can’t have less”.
Entrahepatic metabolism and overall slower elimination of edible cannabis leads to a longer lasting impairment/experience
There’s certainly a genetic element to addiction. I know one individual who tried heroin once and never did it again… I wonder how common that is… others who have managed to maintain a mild cocaine habit (say once every 6-12 weeks) without any detriment. I also know one who smokes cigarettes about 1-2x monthly…
These are obviously exceptions from the norm, as I can name more who have become addicted to and/or died of drug overdoses than I can name who are fine in relation to hard drug use.
Environmental factors are also an underlooked factor, a huge reason as to why some turn to drugs is in relation to a sense of discontentment. I recall seeing a rodent study (and while we aren’t rodents some correlation is possible) wherein a utopic/optimal society was given to rats, they had the option here of living out normal life or taking coke/heroin/whatever… I can’t eemenber the specifics correctly but I do believe the rats were intitiallt exposed to the drugs. After exposure recurrence rates when living decently were very low, however there was a small portion that no matter what… kept coming back (genetic factors).
Many indulge within drugs/alcohol to escape the mundane, painful or depressing aspects of reality. Using substances as a crutch IS a very slippery slope to addiction. And I’m a hypocrite here as I’ve done this very thing before (for example going out and getting drunk because I felt excluded/unwanted within a cohort, the overwhelming sense of rejection inducing emotional pain and thus I decide instead of actually dealing with it I’ll merely repress it with intoxicating substance)… and the problem is, this method works, at least acutely… until you wake up and all you’re problems are still there, but sometimes now they’re compounded and you’ve got work, school etc to go to… but you feel so shit you don’t want to do anything, coupled with the shame from you’re actions be nigbt before it’s somewhat reinforcing to just go back to whatever you were doing initially to block the pain… over time magnitudes of problems build up (if you decide to follow this route)
Sorry for bad grammar, using a shitty oldish phone that I dropped today and thus slightly damaged the screen
You forget that people especially at festivals are extremely irresponsible. And 150 mg is the standard dose. 2 of these tabs and you’re intoxicated at 300 mg. For people who don’t know what they do this is dangerous and two times the normal dose is not a large gap. These were also just two of the adverse events that could happen.
Is it? My friends typically start with 100mg then gauge the effects a couple hrs later
None of my (CLOSE) friends have ever come close to 300mg, I believe 160 was the max they’d ever taken and I was told supposedly the comedown was absolutely horrid
Sounds like you need new friends with better lifestyle choices. You’re too smart to get caught up in such things.
Ehhhhh, I don’t care what they do in terms of recreational drug use. That isn’t my problem, if anything I’ve helped dispense advice relating to harm minimization that has had a positive overall impact
They’re good guys, I judge based on character (as in, whether they’re good people), rather than whether they decide to occasionally pop a pill at a party. So long as nothing is pushed on me that I’m not comfortable with, then I’m okay.
Substance abuse is rampant amongst the teenage demographic, at least where I am I guess… that isn’t a particular excuse, but if it isn’t mdma or whatever it’s copious amounts of booze. I’m not going to drop my friendships because of decisions they make that ultimately have no effect on me
However I do appreciate you’re concern
This is how I lost my best friend though, he became somewhat of a drug addict, either using whatever he could get his hands on or drinking copiously on a daily basis… he transformed from an awesome, funny, outgoing guy full of potential to a shell of his former self… and the transformation was actually pretty quick (say 9 months), who leeched off others, had no reliability and generally did nothing other than make an ass out of himself. After having to pick him out of a rut about four times over the course on 9 days or so, I decided I had to leave him as I couldn’t help him and he’d only drag me down
I am a little out of touch with that scene being 20 years your senior but it wasn’t amongst my choice of friends and I still believe that it’s who you surround yourself with. It may also be as you said… your demographic.
No prob my friend. It just bothers me to see someone so intelligent have so many anecdotal experiences at your age. I’m not implying theyre your fault, but still make sure you surround yourself with like minded folks and don’t get caught up in others poor decision making.
It also disturbs me somewhat, as I do believe I’ve seen far more than I perhaps realistically should have
There’s a time and a place for bad decision making… it’s called college… or brief stints on holiday…
As to my previous post, dropping my best friend was one of the hardest things I’d I’ve had to do, as we had been practically inseparable for many years. However I do believe at the time and Ariel currently it was the right choice to make. He said after I left America once again that he’d realized his faults and that he was going to go sober… this lasted about three weeks
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