[quote]uwacop wrote:
Spinal Muscular Atrophy
[/quote]
Yeah, sorry for the misunderstanding, English is my second language and I suck with the abbreviations. My wife already pointed out what you meant by SMA. One of our friends actually has it (since early childhood).
Indigo-3G and Carbolin 19 sound like some promising compounds for weight loss and overall health.
You could also try a whole foods paleo diet where you dial down the carbs as much as possible while upping the proteins and establishing a moderate fat intake based on what your wife can handle (there are problems with fatty acid metabolism in SMA but mostly in infants)
In your wife’s case, even though she’s stuck with a genetic problem, there may be a possibility this diet would help optimize her cell metabolism and slow her decline (by possibly optimizing SMN2 output). Other benefits would be weight loss and improved overall health, so no reasons to not try it Since she’s not very active carbs should have a smaller place in her diet anyway.
Your wife may actually do better on multiple small meals spread out over the day if she has trouble metabolizing fatty acids. Trial and error should establish that and another reason why high protein may be the way to go (and personally I think it’s healthier for a cell to metabolize proteins than ferment carbs).
The official jury is still out but ketogenic diets are starting to look like a very promising way to overcome or help overcome a range of very serious illnesses, like cancer, MS, Crohn’s and a myriad of other crap, probably by resetting cells metabolisms to their natural state.
In the case of SMA however there are also problems with fatty acid metabolism, so even though a carby diet is not good for anyone in this case you may have to dial back a bit on the fat as well.
It may be initially difficult (energy level wise) to switch to a high protein paleo diet so be prepared to stick with it for at least 8-12 weeks so your metabolism can get used to it.
For paleo diets: An easy read to start with is Robb Wolf’s book, the paleo solution.
Talk to your doctor about this diet, it may be wise to monitor certain blood levels. (I hope your doc is open to the idea)
Good Luck