Is it a bad idea to use a tanning bed when you are already taking Vitamin D say 4-6000iu’s a day?
Are there are negative effects of useing Vitamin D w tanning beds?
I had a long standing skin complexion problem during my teenage years, and it was actually recommended that I consider tanning, even during this I was taking an Anti-biotic for mild acne, which contained Vitamin-D.
I had no side-effects.
Theres a distinct difference between the Vitamin-D you consume versus the natural Vitamin-D your body produces when exposed to sunlight (melanin).
Consult a doctor if you have any existing/pre-existing skin conditions.
I use a tanning bed 2x/week and take 4,000 IUs of D3/day, no problems here. My level stays in the low 60s, which is about the middle of the range for vit D blood levels.
[quote]Oquendog wrote:
Theres a distinct difference between the Vitamin-D you consume versus the natural Vitamin-D your body produces when exposed to sunlight (melanin).
Consult a doctor if you have any existing/pre-existing skin conditions.
[/quote]
Care to elaborate on this?
I don’t think this is true. If I recall correctly, the first step in vitamin D production in the skin is the conversion of 7-dehydrocholesterol to cholecaliferol, which is vitamin D3. Vitamin D3 is what is used in most (not all) vitamin D supplements.
[quote]NewDamage wrote:
Oquendog wrote:
Care to elaborate on this?
I don’t think this is true. If I recall correctly, the first step in vitamin D production in the skin is the conversion of 7-dehydrocholesterol to cholecaliferol, which is vitamin D3. Vitamin D3 is what is used in most (not all) vitamin D supplements.[/quote]
Your right on the cholecalciferol that your skin produces being the same as the kind that’s in supplements, but cholecalciferol isn’t the active form… After cholecalfciferol is produced in the skin it is converted to 25-hydroxycholecalciferol by the enzyme 25-hydrolase in liver hepatocytes. The hepatocytes then store the 25-hydroxycholecalciferol until it’s needed.
When a need arises the hepatocytes release the 25-hydroxycholecalciferol which is then metabolized in the proximal tubule of the kidney by the enzyme 1alpha-hydroxylase into 1,25-hydroxycholecalciferol which is the active form of Vitamin D.
You can only get the active form of Vitamin D by perscription because its actually some really toxic stuff… I’ wouldn’t mess with it because there’s noting fun about metastatic calcification!!! Its usually only given to patients who have chronic renal failure because they often have proximal tubule necrosis… Just a bad deal all around.
[quote]roypw wrote:
Your right on the cholecalciferol that your skin produces being the same as the kind that’s in supplements, but cholecalciferol isn’t the active form… After cholecalfciferol is produced in the skin it is converted to 25-hydroxycholecalciferol by the enzyme 25-hydrolase in liver hepatocytes. The hepatocytes then store the 25-hydroxycholecalciferol until it’s needed.
When a need arises the hepatocytes release the 25-hydroxycholecalciferol which is then metabolized in the proximal tubule of the kidney by the enzyme 1alpha-hydroxylase into 1,25-hydroxycholecalciferol which is the active form of Vitamin D.
You can only get the active form of Vitamin D by perscription because its actually some really toxic stuff… I’ wouldn’t mess with it because there’s noting fun about metastatic calcification!!! Its usually only given to patients who have chronic renal failure because they often have proximal tubule necrosis… Just a bad deal all around.[/quote]
Right - sorry, I wasn’t clear on my question. I was referring to the first step, conversion to D3 in the skin, in relation to D3 supplementation.
Good post though, lots of good info.
It’s impossible to overdose on vit D from tanning; your body will gradually back off the production when it’s reaching high enough levels.
[quote]pinkponyz wrote:
It’s impossible to overdose on vit D from tanning; your body will gradually back off the production when it’s reaching high enough levels.[/quote]
You’re totally right. It would be very hard to cause hypervitaminosis D from tanning… but why you’re right is the really cool part!!! Because as it applies to tanning, vitamin D levels have nothing to do with what is regulating it… and thats just weird!!!
So here goes… Vitamin D is made from 7-dehydrocholesterol. 7-dehydrocholesterol is used by all cells in our body to make cholesterol, because of this it is impossible to down regulate 7-dehydrocholesterol because if that happened our cell membranes would basically suck.
Anyways, there is a ton of 7-dehydrocholesterol in the stratum spinosum and basal of our epidermis. When UVB radiation hits 7-dehydrocholesterol it is converted into Vitamin D3. So the paler you are the easier this can happen because it’s easier for light to penetrate to that level of the epidermis and get all of this going.
Well UVB radiation also stimulates melanin production in the skin which gives you a tan and makes your skin darker, but it also makes it harder for light to penetrate to the levels where the highest 7-dehydrocholesterol are located so not as much of it is converted into Vitamin D3 and serum levels stay in range… Pretty F’in Cool!!!
I get my D3 from Tanning bed and take supps too.
[quote]roypw wrote:
pinkponyz wrote:
It’s impossible to overdose on vit D from tanning; your body will gradually back off the production when it’s reaching high enough levels.
You’re totally right. It would be very hard to cause hypervitaminosis D from tanning… but why you’re right is the really cool part!!! Because as it applies to tanning, vitamin D levels have nothing to do with what is regulating it… and thats just weird!!!
So here goes… Vitamin D is made from 7-dehydrocholesterol. 7-dehydrocholesterol is used by all cells in our body to make cholesterol, because of this it is impossible to down regulate 7-dehydrocholesterol because if that happened our cell membranes would basically suck.
Anyways, there is a ton of 7-dehydrocholesterol in the stratum spinosum and basal of our epidermis. When UVB radiation hits 7-dehydrocholesterol it is converted into Vitamin D3. So the paler you are the easier this can happen because it’s easier for light to penetrate to that level of the epidermis and get all of this going.
Well UVB radiation also stimulates melanin production in the skin which gives you a tan and makes your skin darker, but it also makes it harder for light to penetrate to the levels where the highest 7-dehydrocholesterol are located so not as much of it is converted into Vitamin D3 and serum levels stay in range… Pretty F’in Cool!!![/quote]
Awesome post. It was extremely refreshing to read a post which wasn’t filled with retarded misinformation. Thank you!
[quote]NewDamage wrote:
Awesome post. It was extremely refreshing to read a post which wasn’t filled with retarded misinformation. Thank you!
[/quote]
Thanks!!! I’m currently studying for my first round of board exams so I’ve kinda been using this board to answer some of the more complex questions and keep myself fresh on nutrition and biochem…
So if there’s anything you wanna know feel free to ask. The only questions I won’t answer are the ones asking for direct medical advice.