I’m checking to see if anyone has experience with Wegovy while being on trt and strength training.
A couple of years ago I stopped lifting and taking test and hcg (and a couple of cycles of tren). I had a pretty good physique at 6’3 242lbs and 13% bf when I stopped and I’ve since lost all of my gains and gained quite a bit of fat having all the symptoms of low trt.
I just turned 50 and I’ve recently restarted lifting and a trt regimen but without the hcg. This week my doctor prescribed me Wegovy because of my bmi, hypertension and family history.
I’m not looking to turn into the hulk on 200mg of test (my prescribed dose). But I would like to get to some semblance of what I was before but leaner.
I’m curious if the Wegovy will enhance or be a detriment to what I’m trying to do.
I haven’t been able to find anything on-line about trt with strength training and Wegovy.
My insurance covers all but $24.99 of the prescription and I have a coupon that made the Wegovy free so I’m thinking about trying it. Thank you!
The thing you have to be careful about with these weight loss drugs, is to get enough protein, because you won’t be as hungry, so it’s a double edged sword. Ritalin has this affect on me, and I looked anorexic because I was barely hungry.
I’ve thought about that and agree with you. I expect it to be difficult with little to no appetite. When I eat it would have to be very clean, high protein.
Semaglutide appears to be one of those too good to be true treatments. We probably have about 200 patients using it, with roughly half being men. Some of them were seriously obese. Some have experienced nausea and diarrhea, one overdosed himself. It’s a step up dosing program, so it’s easy to drop the dose back if necessary. Some split the dose and take it twice a week which resolved the nausea.
So far, the most weight anyone has lost is 80lbs. I’m not aware of anyone who has experienced any malnutrition issues.
I’ve used two different GLP meds, currently using Liraglutide (the short version of this). I’m tired almost all the time, from the low calories and the “always full” feeling. This makes training well a chore, I do go on walks for my cardio but even that is getting tired quickly. And bought of low blood sugar if I do too much activity without eating enough.
Will it help you lose weight? Yes. Will it interfere with your training goals? Almost certainly.
I think this comes down to dose, nutrition and goals (don’t be expecting to be hitting bench PRs left and right, unless you’re a newbie haha). I think many are just in such a hurry to be lean that they are doing to much. Where I think it helps is sticking to a 3-4 month cut at a reasonable rate of weight loss.
I think some of the issues in dosing come from medical guidance meant for morbidly obese people that don’t exercise and eat for entertainment / vice / coping mechanism. 2.4 mg/wk of semaglutide seems insane to me. IMO, use the minimum effective dose to keep the weight coming off at something like a pound a week. Use it so that food doesn’t always have to be on your mind when cutting.
Yes that could be right. I think there is a direct impact by tricking your body into thinking you’ve just had a large meal that adds to the low energy. I’m doing about 500-700 cal deficit and I’m just so much more tired that usual
Do you think that could be because of adherence to the diet for a longer time because of the drug?
I think a calorie deficit becomes more difficult the longer it is maintained. The first week at negative 500 kcals at 15% BF is a lot easier than week 20 at 10% (and energy would be lower too). The thing is without the drug, not many people find themselves at week 20 in a consistent deficit. They start eating more, losing slower, just maintaining weight, or even by 20 weeks putting some back on.
It is just my hypothesis TBH. I don’t know that the GLP-1 agonists don’t make some people more tired FTR.
I do know that many people who do manage to get very lean complain of similar lack of energy though.
I am debating in my head on taking a small diet break or continuing on. I know in my frigid state, beach weather is only about 6 weeks away, and I am not as lean as I’d like right now (are we ever though lol).
I guess my reasoning for the break is take a week off and eat more on purpose. I can do that even on the .375 mg of semaglutide, but then hit it hard for about 5 weeks. I worry that if I go on that I’ll basically lose like 1-2 lbs over the next 6 weeks because of diet fatigue. I guess I don’t know that would happen though, and I also don’t know that if I took the week break I’d be super motivated and hit it hard for 5 weeks.
I tried it (Victoza) and like the insulin and type 2 medicines with the exception of Jardiance, it only works on the first dose only, after that it’s either potassium deficiency within 24 hours or no affect at all.
All types insulin cause paralyzing fatigue and weakness, feel extremely hot!
My endocrinologist is stumped and told me he’s never seen anyone respond to these type 2 diabetes medicines like me. If I increase the dose, I get a one time benefit, then nothing. TRT is the only thing that continues to work the longer I’m on it.
Ha, I am in the same boat. I have been on for 5 weeks and am taking 3-5 days off as a break to see if I can get some energy back, then go back in for another 5 weeks. We have a work-related bonus vacation to Bermuda coming up and I wanted to be ALAF for that trip.
It’s kinda funny how diet fatigue still kicks in even without an appetite. I think the mental effects are still there of the constant counting, low-satisfaction eating while on a diet.
This is the conspiracy nut in me, going through my notes, I changed my brand of testosterone 2 weeks ago, and kinda noticed these changes since then. My brain tells me that’s impossible, test is test, and Depo-Test should be just as good as Hikma. But IDK. You start to look at what’s changed and it lines up.
@systemlord made a good point about mineral deficiency as well. I can def tell that medication I take isn’t kicking in like it used to due to the changes in GI system. Maybe some vitamins and minerals are also impacted?
These are all very thoughtful and helpful responses, thank you.
This is making a lot of sense to me. Combined with training and diet I do think Semaglutide should be helpful to get my levels back in order. I think maintaining at a healthy level will be key instead of stepping up the doses if not necessary as has been mentioned by others above. I’m guessing my doctor can stop me at a certain mg if it’s optimal for me. Does anyone know if the compounding pharmacies Semaglutide is identical to the name brands? I’m just curious since it is patented. You would be able to split up your dose etc. with the compounded product and if insurance ever stops paying for it that would be the rout I would go if necessary. Thank you-
I just found some data on beta blockers enhancing, prolonging the effect of type 2 diabetes drugs. I wonder if the beta blocker was the reason for my response to type 2 medicines.
By law I don’t think it can be. The stuff I got from South Lake was always mixed with something. The Semaglutide part is likely the same, but they can’t sell the exact same formulation.
its very new + like the shots pushed for you know what, UNTESTED so you are the beta tester’ intermittent fasting + cutting bad carbs dropped my BP + made all my yearly tests better, except cholesterol the docs opinion which is STILL misunderstood by most mainstream docs IMO
this stuff is one of those too good to be true chemicals. no long term data. once you stop you will regain the weight. who knows what hidden side effects (other then nausea/energy levels). energy to workout might take a large hit. hard to keep protein levels up.
I honestly would prefer an ADHD stimulant over this. i tried a 0.1mg injection months ago…4 weeks taken out of my life. i get that not everybody has this bad exp.
but why not try something like the carnivore diet, where you naturally won’t over eat (while keeping protein decent).
Ppl misunderstand what this medication does. They think it burns fat, or does something unknown or untested to allow you to lose weight. That’s not it. This medicine is what allows you to do IF. It’s what allows you to try carnivore, or keto, or whatever diet du jour is currently trending. This is what allows you monitor calories in. When you say “why don’t ppl just do ,” yeah we know that. This is what makes that possible. The cravings stop, the constant food thoughts stop, the constant hunger stops, and then we can do the things that are needed to lose weight, be healthy, be normal.
This idea that you “naturally” won’t overeat on a certain diet is nonsense. You can overeat on any diet, any plan. If the cravings and the “noise” is there, no amount of beef or cow heart is gonna stop it.
Rant over; it just bugs me when ppl take this attitude that anyone using GLP (or any other weight loss drug) is just missing the ONE DIET TO RULE THEM ALL that will fix their problems. That’s not it at all.
i dont know. I only tried 1 injection once. there is some studies. 2/3 after 1 year.
so you go through chemical hell, loose lets say 30lbs in 6 months. then after 12 you regain 20.
so total in 18 months you lost 10lbs while being in chemical eating straightjacket.
there is also studies that people loose muscle. so in addition now you fucked your lean mass, which will further drive down your metabolism. win/win isnt it