Hey all,
Thanks for your help here. I am really looking for some help and advice to solve my ED problem. It’s an abnormal situation.
I was doing Test E about 85mg/week for about 9 months. Added in two cycles of Anavar for 6-8 weeks at 40-50mg daily. Felt incredibly good and no issues with ED, libido, etc. I woke up one morning and had terrible migraines that I’ve never had before. Never gave blood during the time on TRT but after the migraines I went and gave blood. Had high blood pressure at time of donation but didn’t test hematocrit or hemoglobin levels.
Day after giving blood my migraines subsided but I started noticing when I was having sex with my girl I would go limp and it has progressively gotten worse. I’m trying to figure out what happened because pre-migraines I never had any ED problems. Been off TRT and Anavar since 9/23 where hormone clinic put me on clomid and HCG for atrophy. Saw Endo on 4/15 who said to do only clomid(since I’m looking to have kids) which I’m doing 25mg EOD for about 5 weeks now to reset my body.
Any advice would be greatly appreciated! Here’s some of my labs(4/9/24) below:
Total T: 482 (Range: 240-871)
Free T: 11
SHBG: 25 (Range: 19-83)
Estradiol: 47
These labs are from when? After TRT and Var? Your SHBG isn’t as low as I would expect on Var. Your FT and TT are also pretty low for a TRT regimen, even at trough.
Hey man, thanks for your help. Labs are from 4/9/24. Been off TRT and Anavar since 9/23 where hormone clinic put me on clomid and HCG for atrophy. Saw Endo on 4/15 who wanted me to do 6-8 weeks of clomid only to get a good baseline.
This could be a big factor. You’ve changed something and now your hormones are looking for homeostasis.
Anavar is not part of a TRT regimen. Did they give itto you? If so, IMO look for a new doc/clinic.
Way too much drug pedaling at “HRT Clinics”
How old are you?
1 Like
No I ended up getting the Var from a friend of mine. It seems like after the migraine/high blood pressure episode that is when I noticed the ED which is why I decided to get off TRT thinking it was either that or the Var that caused it. I know a lot of factors here but that was the turning point from what I noticed.
I’m 33, not overweight overall pretty healthy.
The timeline is a little confusing. Do you have current blood work? Your issues with your girl were recent or back in 2023?
Sorry I know the timeline is a little all over the place. TRT/Var was stopped on 9/23 once I had the migraine episode and high blood pressure. A week or so after the episode I noticed I wasn’t able to keep an erection which is why I stopped the TRT and went to Clomid/HCG which I’ve been taking since 9/23. On 3/24 is when my Endo said to only do Clomid to get a good baseline of where my levels are. Assuming at the time of the migraines my hematocrit and hemoglobin were high but would have thought now that they are normal the ED would have gone away but it still persists.
Here’s labs(4/9/24) below:
Total T: 482 (Range: 240-871)
Free T: 11
SHBG: 25 (Range: 19-83)
Estradiol: 47
Thanks for your help!
Gotcha, you just needed to give it another week without the Var. Kinda jumped the gun on stopping TRT and going to two drugs that can also be problematic for libido.
Optimal is 1:1 SHBG:Estradiol.
Have you had your prolactin checked? Cabergoline will fix relatively quickly if too high.
I had sporadic ED and minimal sensitivity. I fixed both of the above and back to normal.
Thanks man. Do we think I just needed to get off the var and stay on TRT when this happened. Hoped after a couple months things would have returned to normal but I know switching my regimen from TRT to Clomid probably didn’t help.
Yep prolactin was checked and came back normal. I’ll see about getting an AI once I can get updated bloodwork. Thanks for your help
1 Like
Interesting, I’ve never heard this before. Can you expand on it a bit?
This was according to a consult I had at Defy recently. I had never heard of that either and haven’t had time to research.
I had two issues. High prolactin and high estradiol (high absolute value also) to SHBG ratio. Solved both so not sure exactly which was the issue. Likely both.
Oh interesting, never thought about that. I could try that next.