To Supplement Gurus

I have recently been told by a colleague of mine that Cayenne aka Capsicum can be an extremely powerful herb used for various reasons such as : Fat-Loss, Improve Circulation, blood pressure regulator, reduce in inflammation, and treat muscle soreness after workouts. Do any of these claims have any validity? Should I make it a must-have in my daily regimen?

Various google searches have given me hokey-pokey homeopathic sites all selling various “natural” products, but nothing concrete. Any help would be appreciated.

I know enough to say if you are going to expieriment, go easy with that substance…

There’s an article in the new Scientific American that makes similar claims about Cumin. No doubt they will raise your metabolism somewhat but I wouldn’t expect miracles. If nothing else, they taste good and may open up new culinary avenues.

Like the previous poster warned: be careful experimenting, especially if you’re trying large doses in capsules, that stuff can burn on BOTH ends.

[quote]Kruiser wrote:

Like the previous poster warned: be careful experimenting, especially if you’re trying large doses in capsules, that stuff can burn on BOTH ends.[/quote]

That Ring of Fire!

[quote]HandOfGod wrote:
I have recently been told by a colleague of mine that Cayenne aka Capsicum can be an extremely powerful herb used for various reasons such as : Fat-Loss, Improve Circulation, blood pressure regulator, reduce in inflammation, and treat muscle soreness after workouts. Do any of these claims have any validity? Should I make it a must-have in my daily regimen?

Various google searches have given me hokey-pokey homeopathic sites all selling various “natural” products, but nothing concrete. Any help would be appreciated. [/quote]

Actually, there’s some great animal data that shows an increase in BAT thermogenesis; apparently acting via sympathetic upregulation.

In humans, there’s less data, though enough to show that when the proper capsaicin active is used, there’s an increase in thermogenesis.

I haven’t done a thorough review of capsaicin in a while, but I recal an interesting study that came out in, I think, 2000, that showed when women consumed 3mg active capsaicin w/ meals, thermogenesis increased. The interesting part was that capscacin appeared to work better in lean, as opposed to obese subjects when consumed prior to meals.

If you’re interested in doing a more recent review of literature, I’d recommend you stop doing general web searches, and just go directly to PubMed. It’s far more technical, but also far more accurate - it’s an NIH site that contains links to practically every published research worth reading.

BTW, I think the dosing in animal studies, as well as human studies, have run up to 3mg, per kg bodyweight; if I recall, the effect was dose-dependent in rodent models, but I don’t recall any such specificity in human studies.

The sidenote, as has been mentioned previously, is that capsaicin “burns”. Yes, you’ll get a warming sensation - that’s the thermogenic effect - but if you take a dose too aggressive, don’t expect anything different than had you downed too many jalopeno peppers.

As a personal suggestion, I like using capsaicin and things along that line. The thermogenic effect is quite noticeable - which, from a marketing standpoint is good - and there are some nice side benefits of such: antioxidant capacity & GI motility, as well as aiding in those who suffer from motion sickness.

Hope this has helped. - chris

[quote]Lockwood wrote:
Actually, there’s some great animal data that shows an increase in BAT thermogenesis; apparently acting via sympathetic upregulation.
[/quote]

how much BAT do humans have as a percentage of adipose tissue? not very much after infancy.

though it may certainly help upregulate some pathways, i doubt that the extract on its own will be ridiculously powerful (i mean compared to HOT-ROX Extreme and the like). there definately seems to be a strong thermogenic effect and as for the dose dependence and such, animal models utilizing rodents for thermogenesis experiments should be taken with a grain of salt as they have much BAT which adult humans do not. this will skew results if we try to apply from rodents to humans.

good point about going straight to pubmed.