Time line for TRT results?

Hello, I was wondering if those who have had experienced hypogonadism followed by testosterone replacement therapy could tell me a general time line for how the results came.

Stats:
Age: 18
Pre-HRT Testosterone: 271
Protocol: 100mg per week divided into two doses per week.

I’ve been on TRT for 2 weeks now.

When could I expect the following?

-Improvement in Lean Body Mass / fat storage in chest/abs
-Improvement in Libido
-Improvement in mood
-improvement in depression/anxiety

etc.

[quote]jdinatale wrote:
Hello, I was wondering if those who have had experienced hypogonadism followed by testosterone replacement therapy could tell me a general time line for how the results came.

Stats:
Age: 18
Pre-HRT Testosterone: 271
Protocol: 100mg per week divided into two doses per week.

I’ve been on TRT for 2 weeks now.

When could I expect the following?

-Improvement in Lean Body Mass / fat storage in chest/abs
-Improvement in Libido
-Improvement in mood
-improvement in depression/anxiety

etc.[/quote]

When you say “TRT,” I assume that you are on T only, correct? Everyone is going to be different based on their situation prior to treatment. I, for example, was a mess. I initially had to address some of the lowest T levels my doc has ever seen as well as correct adrenal issues. A couple months later I started adjusting my thyroid levels.

I think around the 9 month mark, after testing and adjusting dosages a few times, I started to really notice big improvements in libido and mood. Monitoring how I felt at different estrogen levels was imperative in dialing in libido and mental clarity. Thyroid hormones, in my case, seemingly plays a large part in depression. Anxiety is something that I am still working on and having the most trouble with, but it is certainly much better than before HRT.

Continue to educate yourself about how hormones work and observe how your body reacts to treatment. Good luck.

The outcome depends on one’s E2 levels and management.

Ok pre-treatment, my E2 levels were 31…does that help?

Read all you can and let time tell you how you are doing. It takes time for level to change and dose changes to take affect. This is a life long treatement so expect it to be onging education

E2=31 can create estrogen dominance problems when T is low. I had low T, as an old guy, with pre TRT E2=17 and I have obvious estrogen problems. With your injections, E2 has nowhere to go but up. It is very likely that you need active estrogen management. Read the protocol for injections sticky and find the book referenced there ‘the testosterone syndrome’

[quote]jdinatale wrote:
Hello, I was wondering if those who have had experienced hypogonadism followed by testosterone replacement therapy could tell me a general time line for how the results came.

Stats:
Age: 18
Pre-HRT Testosterone: 271
Protocol: 100mg per week divided into two doses per week.

I’ve been on TRT for 2 weeks now.

When could I expect the following?

-Improvement in Lean Body Mass / fat storage in chest/abs
-Improvement in Libido
-Improvement in mood
-improvement in depression/anxiety

etc.[/quote]

I went/am still going through a hypogonadal period. The recovery is not instantaneous. Although I am working on restoring levels naturally, the first thing I am noticing is a return in chest hair and an increase in the rate of beard growth. These are surefire indicators that rising androgen levels are taking hold.

If you have been low for a long time, you should feel the effects pretty quickly, and I’m guessing it would be in the energy department first (assuming estradiol levels are held at a reasonable level.

Depression might take a while longer. It takes some time for your brain to heal. Yes I said heal b/c depression does physically damage your brain (shrinking hippocampus).

Anxiety would indicate “adrenaline dumping.” Testosterone is a calming signal. It should help you out provided, once again, that estradiol is held in check.

You must also realize that pumping your system full of testosterone WILL NOT make you feel better if other systems in your body are not optimized FIRST. If your adrenal glands are underactive, high levels of testosterone will make this condition worse and you will feel very bad. If your adrenal glands are overactive (too much cortisol…hypercortisolemia), you can run into low T and a variety of other problems.

If your thyroid is underactive, you will feel bad. I beleive that increasing testosterone levels will lower thyroid activity.

You need to ensure that your adrenal glands can handle the T. Do a 24hr saliva cortisol test if you haven’t already.

Get a full thyroid panel done, if you haven’t already

BTW, you are very young (18). Have you determined if it is primary or secondary hypogonadism? If secondary, get pituitary checked out to rule out hypopituitary. What’s your diet like? I really hope you covered all of your bases before hopping onto TRT at 18.

Chem