I recently started a cycle of Test E 8 days ago and a week or more before that I started my letro to make sure I did not have a problem with gyno… The Letro has killed my sex drive… when will the test e start working its magic on the libido??
I already notice some strength gains and energy and an overall better feel but I’m looking forward to the spike in Libido? I have heard around two weeks is that about right… I been going 250mg e/3days. Anyone with similar exspirience that can let me know a estimate would be helpful?
How much letro are you taking now? You may need to adjust it. Lowering estrogen too much will kill your sex drive. I think starting letro a week before using a long(ish) ester like enanthate was a mistake (especially if you started dosing it at the level you planned to use during the cycle).
regarding the above post:
Well I had heard and got advice that said the Letro takes a while to build up so the advice I got on here was to start it a week before at a lower dose and pick it up as I started my cycle so I was doing like 1.25 mg then bumped it up to about 2mg a few days ago… Anyway I’m prone to gyno and had it in the past so I really wanted to make sure I did not get it again… Do you think I should lower it? Or wait and see when the test kicks in? How long untill I start noticing the effects of the test on libido?
[quote]Smitty22 wrote:
regarding the above post:
Well I had heard and got advice that said the Letro takes a while to build up so the advice I got on here was to start it a week before at a lower dose and pick it up as I started my cycle so I was doing like 1.25 mg then bumped it up to about 2mg a few days ago… Anyway I’m prone to gyno and had it in the past so I really wanted to make sure I did not get it again… Do you think I should lower it? Or wait and see when the test kicks in? How long untill I start noticing the effects of the test on libido?[/quote]
How often are you taking 2mg?
I assume you had non-AAS induced gyno. Figuring out the right AI dosage can be tricky. I think you can try lowering it but be very cautious of gyno symptoms. If you lower it and gyno symptoms show up you will obviously up the dose again.
PLEASE WAIT FOR OTHERS TO SHARE THEIR OPINIONS BEFORE DOING ANYTHING. I am not the brightest or most experienced guy here.
I have no idea how long it will take for the libido enhancing effects to kick in. Things like that are very individualistic.
I got my gyno from pro-hormones and possibly from tren that I took that messed me up I was in college and playing and got hurt and some trainer/teammate told me I could play through my injuries with tren and some pro hormones that were similar to test, well the tren or prohormones gave me gyno I had no clue about gyno at the time and was only taking nolvadex XT post cycle from the GNC I was so stupid…
The moron who got it for me was not to bright obviously but neither was I for taking it, but I thought it would help me play with my injuries and so I did it… Anyway that was when I started doing my research and took letro… It helped and got rid of it pretty well to…
So I learned my lesson on not doing some research that was a couple years ago and have been trying to learn more since then… as for the other question I’m taking the Letro everyday… Anyone else have any suggestions or input on how long it takes roughly for the libido effects of test e to kick in?
On 2 mg of letrozole per day, probably never with regard to when libido will kick in.
Individuals will vary but as a guess at your level of testosterone use more like 3/4 mg per day would be about right.
I would suggest discontinuing letrozole use entirely for 5 days to allow levels to fall to a perhaps-correct level and then try using about 0.75 mg/day. That being a rough figure: a slighly lesser value if more convenient could just as well be chosen.
[quote]Bill Roberts wrote:
On 2 mg of letrozole per day, probably never with regard to when libido will kick in.
Individuals will vary but as a guess at your level of testosterone use more like 3/4 mg per day would be about right.
I would suggest discontinuing letrozole use entirely for 5 days to allow levels to fall to a perhaps-correct level and then try using about 0.75 mg/day. That being a rough figure: a slighly lesser value if more convenient could just as well be chosen.
[/quote]
Thanks again Bill, I will back it down as you suggested and start it at back up .75 mg or less from now on… The reason I was taking a bit more was because I was so worried about converting to estrogen from the last time when I did not use it… Also, this was the dosage I was using to cure my gyno and now since I have it under control I suppose it would be beneficial to back it off unless it starts to get bad again… Thanks again…
Don’t expect results right away. My personal experience with letro suggests that it is extremely effective, but can also be too extremely effective.
I have had two distinct libido crashes from letrozole. Both of them took weeks to fully recover from. It’s no joke, the compounds you are playing with.
Hope this helps as a guideline. It is the next best thing to a good blood test. Actually, the way you feel is more indicative of where your personal threshold is at.
Individual response to letro us highly variable. That makes dosing recommendations and dose experience sharing sort of useless. It is often termed “harsh” as it can kill E2 very easily. Arimidex/anastrozole is recommended as its effects are more predicable.
Note that some are adex over-responders who need to take 1/4th or 1/8th of the expected dose. I would expect that others with that genetic makeup would be hit very hard with letro.
Dose response to adex is reasonably linear which allows one to make good dose change calculations based on serum E2 lab results. I do not
In a TRT context, serum E2=22 pg/ml seems to be optimal from a libido point of view. Libido responds well to E2 changes and libido can be a barometer for general well-being.
Higher estrogen levels will increase body fat and fat deposition patterns.
Elevated serum E2 in the mid thirties [0-54 pg/ml] can mess up mind and body. Elevated E2 can lead to many of the same symptoms of low testosterone, even when T levels are high. The effects on the brain/mind build up over time. For a cycle, one might not recognize what is going on. In a TRT context, these problems can be serious and lead to ED and depression - with high T levels. When a TRT guy with elevated E2 is put on adex and gets E2 near 22 pg/ml, there are profound changes that can take two months to resolve. Brain tissue changes and mental patterns and mood take time to complete.
A post PCT estrogen rebound can also rob one’s libido and mood. This is why I suggest a post PCT TRT dose of adex, 0.5mg/week, for an indeterminate amount of time, tapering out later. You will have to find your own way through that.
Individual response to letro us highly variable. That makes dosing recommendations and dose experience sharing sort of useless. It is often termed “harsh” as it can kill E2 very easily. Arimidex/anastrozole is recommended as its effects are more predicable.
Note that some are adex over-responders who need to take 1/4th or 1/8th of the expected dose. I would expect that others with that genetic makeup would be hit very hard with letro.
Dose response to adex is reasonably linear which allows one to make good dose change calculations based on serum E2 lab results. I do not
In a TRT context, serum E2=22 pg/ml seems to be optimal from a libido point of view. Libido responds well to E2 changes and libido can be a barometer for general well-being.
Higher estrogen levels will increase body fat and fat deposition patterns.
Elevated serum E2 in the mid thirties [0-54 pg/ml] can mess up mind and body. Elevated E2 can lead to many of the same symptoms of low testosterone, even when T levels are high. The effects on the brain/mind build up over time. For a cycle, one might not recognize what is going on. In a TRT context, these problems can be serious and lead to ED and depression - with high T levels. When a TRT guy with elevated E2 is put on adex and gets E2 near 22 pg/ml, there are profound changes that can take two months to resolve. Brain tissue changes and mental patterns and mood take time to complete.
A post PCT estrogen rebound can also rob one’s libido and mood. This is why I suggest a post PCT TRT dose of adex, 0.5mg/week, for an indeterminate amount of time, tapering out later. You will have to find your own way through that.
[quote]KSman wrote:
Individual response to letro us highly variable.
[/quote]
Do you have proof of this?
If this statement is true for Letrozole, I would assume that it would hold true for every drug known to mankind.
Do you have proof of this?
If some populations “over-respond” to Anastrozole,you are essentially saying an individual’s response to the drug is variable. If this is true wouldn’t your statement about Letrozole also hold true for Anastrozole?
I feel great besides the low sex drive… I’m not achey at all I have great mental clarity and feel awesome I will stop the dose for a few days and then take much less under 1 mg of letro per day and see how that works… Since I have only been on it a couple weeks and the test 8 days or so I’m sure that the test will boost it a bit regardless and the backing off the high dose of letro will help as well… I appreciate all the help from all of you guys keep the info coming its good stuff.
Libido is a very individual thing. I had very blotchy libido during my test e cycle too. Ironically, now at the end of week 2 of my test taper pct, libido has been much more consistent on doses ranging from 100 mg/w (for 4 stasis weeks) down to the current 60mg/w. I am still using a minimal dose of 0.5mg/w Adex to avoid estrogen rebound.
[quote]W.H.B. wrote:
KSman wrote:
Individual response to letro us highly variable.
Do you have proof of this?
That makes dosing recommendations and dose experience sharing sort of useless.
If this statement is true for Letrozole, I would assume that it would hold true for every drug known to mankind.
Arimidex/anastrozole is recommended as its effects are more predicable.
Do you have proof of this?
Note that some are adex over-responders who need to take 1/4th or 1/8th of the expected dose. I would expect that others with that genetic makeup would be hit very hard with letro.
If some populations “over-respond” to Anastrozole,you are essentially saying an individual’s response to the drug is variable. If this is true wouldn’t your statement about Letrozole also hold true for Anastrozole?[/quote]
In regards to both the anastrozole and the letrozole both compounds are created from pharm companies, available to buy in powder online, and also available from research chemical websites… The quality of the product and subsequently its effective dose is likely to change. That it to say that .25mg/EOD from a reliable source might be equivalent to what is said to be .5-1mg from any of the number of research chemical sites. (as obv each company will have its own accuracy). This is how I would account for the idea that anastrozole has “over-responders” and also the idea that sharing dosages in regards to letrozole is useless.
[quote]Dynamo Hum wrote:
Libido is a very individual thing. I had very blotchy libido during my test e cycle too. Ironically, now at the end of week 2 of my test taper pct, libido has been much more consistent on doses ranging from 100 mg/w (for 4 stasis weeks) down to the current 60mg/w. I am still using a minimal dose of 0.5mg/w Adex to avoid estrogen rebound.
On cycle (11 weeks). I was at 580mg/w test e.[/quote]
Yes I was using 25mg proviron/d from day1 and then upped the dose to 50mg/d for weeks 7 through 10. dbol 30mg/d for the first 5 weeks. 250iu EOD hCG all through. 580mg test /w all through.
I don’t mention the proviron for just that reason. I never felt the purported benefits of it at all?
hCG kept the testes plump, but libido was really weird. At one point I wasn’t getting very hard, yet I was on a hair trigger for ejaculation? Very weird and not in a good way.
[quote]W.H.B. wrote:
KSman wrote:
Individual response to letro us highly variable.
Do you have proof of this?
That makes dosing recommendations and dose experience sharing sort of useless.
If this statement is true for Letrozole, I would assume that it would hold true for every drug known to mankind.
Arimidex/anastrozole is recommended as its effects are more predicable.
Do you have proof of this?
Note that some are adex over-responders who need to take 1/4th or 1/8th of the expected dose. I would expect that others with that genetic makeup would be hit very hard with letro.
If some populations “over-respond” to Anastrozole,you are essentially saying an individual’s response to the drug is variable. If this is true wouldn’t your statement about Letrozole also hold true for Anastrozole?[/quote]
I would like to answer my own take on this.
Yes everyone is different and everyone responds to all drugs different
the dosing suggestions are just that,suggestions.
they are what normaly works but are in no way set in stone.
some will take more and some less.
example my mother takes 1 benadryl and shes knocked out cold.
I have to take 2 of the same dose to get the theraputic amount from allergies.
if I take 3 im asleep like with her one.