I am interested In supplementing with t3 In the future with my next cycle, I have read different articles online regarding dosages, and side effects, however I can’t find a clear cut answer if it will likely permanently shut down your thyroid after use or not, lots of contradicting info. I plan on only using 25mcg if I do go ahead with it, and only for 4 weeks. Has anyone here used it without a prescription? If there is a high risk of permanent shutdown I am not going to add it in the mix.
Highly unlikely that you’d be permanently shut down from using it in the way most people do. The real question is why will you be doing this? Because unless the answer is “I’m competing” it’s not going to be a good enough reason to mess with your thyroid. Looooots of shit can go wrong when you go down that road.
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No real risk of permanent shutdown. Also no guarantee of results. I assume that you want to take T3 for weight loss, but I have never found it to be very effective for that. I’ve used doses up to 75mg and not really seen any difference. And before anyone is a smartass, it was pharma grade, lol.
Thyroid hormone stacks with your natural production. There is no shutdown at all.
It’s also incredibly catabolic. Take too much and it will break down your muscle. It’s powerful enough to catabolize muscle when in a heavy steroid cycle. Consider taking clen instead if you’re doing it for fat loss.
I tried Clen for a couple weeks before and could not handle the sides, I was getting mad anxiety, jitters and kept dropping things even at a low dose. I’m already down to ~11% body fat, just wanted something to help get down to single digits. The more I look into it the less interested I am though now.
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You pretty much have to start at 5mcg and taper up. But yeah. I’ve heard it’s pretty shitty for sides. I have some, but am afraid to take it, Lol.
Best bet is probably test + anavar or winsterol + masteron / proviron with a small calorie defecit if you want to be on cycle. Otherwise, just calorie defecit with caffeine and synephrine.
Eat less, combined with some low dose test and medium dose mast or anavar. Way easier than messing with your thyroid. Unless you’re competing it makes no sense to take those kind of risks.
PS I’m pretty fat right now (stress really is the ultimate killer) so me saying “eat less” wasn’t meant to be snarky. It’s just really the only way. I’m doing it right now and it sucks, but at least I’m not feeling like I lost my mind because I loaded up on crazy drugs to try to do what I know can be done with a plan and willpower. If you’re at 11% you have discipline. Use that to get to 9%. You have the power within you. Don’t doubt your vibe.
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Thanks for the replies guys, I’m going to go with the advice and keep the thyroid meds out of my cycle. Recovery after is hard enough sometimes without throwing my thyroid out of whack lol
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Sorry yes micrograms. Bulking=fat fingers=typos.
IMO, having blood work showing you need it, is justification, but I’m this context that is very unlikely. I have the blood work showing I likely need it, but am tapering off of it because I just don’t want to run it forever. I think with the body recomp, that my thyroid will improve.
Totally agree. If it’s medically justified then carry on. But when it’s just about our own vanity—and that’s what 99% of steroid users are in it for, myself included—it’s simply not worth the risk.
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Holy balls that is a lot of clen. A lot for most people is 100-150 mcg. This dude was taking 1,500 mcg.
With that stack of drugs I doubt I would be able to sleep. It sounds absolutely horrible. It would feel like what I imagine being on meth would be like, while stuck in a sweat lodge.
It is a lot for sure but I think it’s more of a testament to how fast beta adrenergic receptors desensitize. Going from 20 mcg to 1.2 mg in 6 months is a 60 fold increase. If you’re looking at the average clen user they always start at 20 and go to 120 mcg in about 6-10 weeks. So in 6 months I would expect him to be at like 300-500 mcg if the increase is linear but it isn’t. Receptors desensitize exponentially ( B = S - (S-B0)e^-kt ) which means that you need to increase the dose more and more. That’s how you end up with 1.2 mg a day and you have the same side effects as you had all along. They desensitize too.
I gotta point out 2 things here.
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Taking Clen is retarded. Taking Clen for more than a few weeks is beyond retarded. Beta-sympatomimetics have a direkt cardiotoxicity and decrease the oxygen supply (here: ratio) to the heart during exercise. They induce irreversible changes in the myocard. That this guy didn’t drop dead is a wonder.
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The desensitization effect is linked to point 1. It’s a survival mechanism that prevents the heart from being under constant adrenergic stimulation which is exactly what you do with Clen (half life!).
IMO desensitization/tolerance is a remarkable process.
I read two case studies with Z-Substances and there is a guy who went from 10 mg/day to grams per day in a few weeks (more than a hundred pills a day). (In this case it’s not a simple desensitization but it is still a tolerance build up that is extremely fast.)
Desensitization is a process that is worth getting to know too. For example receptors can send signals into the nucleus after they are encapsulated in endocytosis. And that’s just one of the spooky things going on during this complex process. Good work has been done on the desensitization of beta-adrenergic receptors and u-opioid-receptors for people who want to look it up.
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No matter how many times this is said there are still guys who use it. Then when they don’t get the results they wanted they step up to DNP. It’s insane what non-competitors will do in order to avoid dieting.
One thing was not mentioned explicitly in this thread: Clenbuterol and T3 work synergistically. Your post mentioned it but I’ll break it down for simple understanding. T3 upregulates beta adrenergic receptors on which Clen acts. This means the body is more sensitive too adrenalin while you feed it with high doses of it (Clen).
This is a double whammy for the heart.
Take these two together and you increase the risk of heart disease dramatically.