Starting TRT Over Soon

Sorry for the error above @Gibbon (I input 300 mg/week every 7 days instead of the 300 mg you were doing every 28 days approx.)

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Very likely you were up close to 3000 ng/dl at peak and now the 755 ng/dl 10 days after injection makes sense.

Sorry for confusion previous graph caused.

Graph as made assumes HPTA shut down from beginning and your injection frequency was long enough where TT levels don’t build up over time from accumulation due to previous doses. Nevertheless, the graph above would be representative after a few months where you would have no endogenous T being produced.

1000

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Assumed inputs/parameters for the absorption/elimination PK model:
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My pleasure and I hope you feel better soon.

“Better” is not good. Yeah I’d say you need TRT.

Thank you. Better is still below the minimum and the total was at 142 or so yeah I need it and it is helping so far.

@highpull Do you have a rough estimate of the average levels those males are hanging around at? The ones doing the 150+ mg per week.

Wow it’s not like I just made a graph of that :sob: pulling in @highpull 's practice data.

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@cliteastwood is right. I am an idiot to make this stuff and posting it. Few really read it or understands it. My bad.

@cliteastwood what’s your numbers, we will add you to the graph. :rofl: Please follow the guidelines in links below.

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Yeah dude a few sentences summary would do wonders lol. I just saw highpull post the doses here and was wondering the average level.

Do you see it above?

Dude I just want to see a simple “the average levels for the guys I see treated is X” based all on highpulls patients. I woke up with a major headache and brain fog today.

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Good question though. I look forward to his response. I hope you feel better.

Not really, hard to tell by referencing my color on the graph.

It’s hard to predict levels based on dosing. I see guys taking the same dose as I with levels below and above mine. Plus, guys taking more who run lower levels, guys taking less with higher levels.

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This statement puts you out of touch. Other forums countless men at 100 and stay there and feel good.

Maybe your patients are of a certain type.

@tareload also has shared data that 100 puts men at upper range and sometimes over.

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This makes sense because we are too attached to doses. In this case all those patients are technically not on the same treatment. Pretty much an attachment to any dose between 100-200 doesnt make any sense due to variabilities.

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I will just leave this here for anyone interested.

This conversation is becoming precious.

Here is your answer:

150 mg/week…low 700 ng/dl, mid 1200 ng/dl, high 2000 ng/dl (these are all mean TT levels)

Where you fall depends of your fT elimination rate and SHBG.

Physiologic range (quite generous on the upper limit) is 300 to 1200 ng/dl.

I drew a picture. 150 mg/week is not a replacement dose for good fraction of men. 200 mg/week even more silly. 100 mg/week or below puts almost everyone within range. Whether you want to be in range is another story. There is no mystery here when you run the numbers.

I actually plotted some members above so you can see where they sit percentile wise in the distribution. Enjoy.

Maybe one of the silliest statements ever uttered on this forum:

Brought to you by our sponsors…math, critical thinking, and human physiology. And now we have a graph in case someone needs that.

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Out of touch? So be it then, however I think the opposite. That is not my experience. I have to rely on my experiences and what is best for the person in front of me. I’m going to listen to patients speaking to me face to face and what they say will carry more weight than what anonymous individuals report on the internet.

I don’t see how that could be accurate. I see a lot of different types. I do have guys taking 100mg a week and if that make you guys happy, fine (could I be “in touch”?). I have guys taking 200mg weekly and I suppose, with them, I’ll have to be out of touch.

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How many would you say use AI???

Less than 5%.

I actually think you are very much in touch FWIW. Got an more of those data sets? Randomize and take 10% even if you have say 5000 samples. We are building a tool not available anywhere else. Thanks!

I am in correspondence with another big name TRT outfit and will be presenting those data as well.

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Looks kinda familiar:

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The out of the touch remark was regarding the statement that starting at 100 is a waste of time.

AND
that those starting at 140-150, 95% of those need to go higher if they need a dose change.

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