Starting TRT Injections. Any Issues I Need to Be Aware Of?

Rise80, We’re currently looking to keep me on the upside of average on the T. I’m getting shots once every 2 weeks to start.

I know T production will drop so not literally what he meant. We’ll be performing blood work I weeks out to keeps an eye on things

Every other week is going to be a rollercoaster. Needs to be once per week minimum.

You won’t know this yet but when you really start hating life tell your doc you’re going to once a week (twice a week may be better). Make a mental note of this.

This planned course of action your doctor has laid out before you is guaranteed to cause suffering. My suggestion is locate a doctor that has experience prescribing TRT or you will have to figure out your own case. The half-life of T-cypionate is 7-8 days, so this dosing every two weeks makes no sense.

I seriously doubt your doctor ordered the necessary lab work (Total T, Free T, estrogen and SHBG) before going forward with TRT, but you should hit the brakes for now and do a little more research because it sounds like you are overly trusting of doctors.

You need to see if your doctor is competent enough to manage your TRT therapy, often doctors target midrange TT levels which keeps men’s testosterone levels suboptimal and symptomatic, this is especially true for those men with high SHBG needing higher levels to achieve symptom relief.

Hormone profiles after intramuscular injection of testosterone enanthate in patients with hypogonadism

In fact, the present study confirmed serum levels of T which were lower than pre-ART value levels on day 14 after administration. Therefore the further decrease in serum T levels on day 14 after administration is considered to relapse of hypogonadal symptoms and to reduce the patients quality of life.

You don’t know your protocol ? Are u serious , “hey doc give me some of that drug , ok thanks cya … “ and you know nothing about it ?! May want to call and be more observant next tine or ask some questions

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When someone has brain fog and extreme fatigue it’s usually thyroid. T also does it but when someone uses words like extreme it usually ends up being the thyroid.

You need a new doc if he injects you every team weeks. You have so many docs and clinics out there that will give you T to take home. Docs do this in the office because they can bill insurance and make extra money because they are doing this for you.

What a stupid doc who doesn’t even know the half-life of the medicine he’s putting in your body.

Sick

Systemlord, The doctor ran a large blood panel and was concerned about thyroid and T based on my symptoms. I didn’t feel like providing the forum an in depth medical history so there was more discussed in the visit that led him to believe that I should be tested for low T

All the items you listed were in the blood testing. TRT I know nothing about so that’s why I was asking the forum and have been doing research. Yes I did jump into taking injections but the doctor told me this was relatively safe and he could give the 1st injection that day. The way I’ve been feeling over the past few years I was ready for a leap of faith if it would help.

Having injections every 2 weeks seems common practice per most of the medical sites. I’m only seeing people on forums recommend weakly injections so I’ve been skeptical about the necessity of weekly injections. I’ll keep researching and see how I’m feeling before changing things up for now.

I was prescribed 100mg of testosterone cypionate every 2 weeks. The drug manufacturer recommend this mucle injection every 2-4 weeks at 100-200mg. Sounds like my doctor has me aligned with this but I’ll talk to him based on how I feel when I get my next injection

So by not posting all relevant lab values, you are getting less useful advice from our knowledgeable members and are getting less out of this experienced. I see this often, men are coming back months later asking when they are not feeling the effects of TRT and they finely post their labs and learn that what they thought was normal is not normal at all.

Sorry testosterone cypionate

Still it’s not enough, you won’t find anyone on any forums injecting 50mg weekly! The average weekly total dosage is 100mg weekly, some choose to split it up into more shots.

There is no nice way to tell you this, your doctor is an idiot! You have a long road ahead of you before you start feeling good again, it’s not going to happen anytime soon working with this doctor of yours.

I’ve been here for over 3 years and have seen your situations like yours end badly, I’ve never seen these every 2 weeks protocols work, let alone at 100mg every 2 weeks.

Don’t be naive, listen to what these members are telling you. We are speaking from personal experience and the experience of everyone who finds there way to this forum. If you see members on forums telling you some that contradicts what these institutions are doing, this should be a cause for concern.

Your levels will be lower than pre-TRT soon and they will remain there until you force a change.

50mg a week isn’t going to do it for the vast vast majority of people. I doubt you will yet anything out of that dose.

I’ll talk to my doctor. Definitely appreciate all the advice.

Odd that every recomend dosage for this medication on the medical websites that I’m finding is 100-200mg every 2 weeks for muscle injections

And that’s why I see post after post after post on here and on Facebook of people saying “I felt great the first week then back to how I was for a few days then worse for the last 3-4 days, why?”

Over and over and over

I don’t know why they recommend that, but it’s stupid. Just look at the half life… 7-8 days, so you’re down to 25% of what you started with by the time you get to 2 weeks.

I have low SHBG (14) and must inject daily when on TRT. There’s a reason why I asked about your SHBG, it’s critical and the centerpiece for every hormonal evaluation. Your doctor specializes in other areas of medicine and probably doesn’t prescribe TRT often.

Dig a little deeper and do more research and you’ll see what we are telling you is 100% the truth.

Do the math, 7-8 day half life, then look at the study I provided, look at the figure 1 graph B, 6 days after an injection levels are below the therapeutic ranges and by day 14 levels are at pre-ART levels. This is at 200mg every 2 weeks, your levels will be at pre-ART levels much sooner because your dosage is half the dosage given in the study.

Once your natural production is shutdown, you are screwed at this dosage, you will quit TRT, anyone would. You’ll be back here in 1-3 weeks saying, “you guys were right” because it happens all the time across multiple forums.

Here’s how it’s done, pre-TRT estrogen and SHBG are factors in selecting an appropriate protocol, if estrogen is between 20-35 when testosterone is low, then if you double or triple testosterone, estrogen is expected to increase substantially therefore causing negative symptoms.

You doctor doesn’t how to managed men on TRT, this is where the guidelines comes in to play, only the guidelines are part of the problem and are outdated. If you doctor does anything other that what the guidelines state and something happens to you, he gets in serious trouble.

If you doctor follows standard of care and something happens to you, he is shielded from getting in trouble.

I also do apologize if I sound standoffish on suggestions my members here. Typically I trust drug manufacturers recommend usage over forum members but definitely taking a close look into all suggestions by members here

No apologies needed, that’s a symptom of low testosterone, standoffish and low motivation in everything you do in life. Usually with everything except testosterone, you can pretty much trust dosing recommendations.

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I know it’s difficult when you are going through all this for the first time. And shots especially can be scary.

There is a lot of bad advice out there. On forums. On websites. On blogs. You are absolutely right to be skeptical. Many doctors know more than some on here like to admit. But I can tell you the advice you have so far in this thread is as straight up correct and useful as you will get.

The standard starting protocol is 100mg per week, once a week. Many doctors differ in frequency. Three weeks in to getting 100mg every two weeks, you are going to be miserable beyond belief.

I am no internet doctor or regular doctor but you need to get an explanation for the dose. Your T production is going to shut down completely. You need a full replacement and then some. I rarely speak in absolutes on here, nor about subjects I’m not sure about. Unless you weigh 65 pounds, your dose won’t cut it. You are going to be miserable beyond what you can comprehend right now.

Your doctor does seem to think you can “top off the tank” literally like I questioned. I believe that at trough between injections with that dosage, you will be near or below your current levels that you’re currently seeking relief from after your own production shuts down.