Good ol soviet german doping programs. As thorough as us Germans are, the documentation is a major contribution to PEDs in pro sports.
Nice read
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Man the GDR was meticulous.
Testosterone esters played, and still play, a significant role in Olympic sports. Before 1974, such drugs were primarily used as merely another group of anabolic-androgenic steroid preparations. However, after the introduction of in-competition controls, albeit infrequent, in the mid-1970s, testosterone esters suddenly gained special importance as undetectable alternatives to be used for “steroid bridging” (also known as “bridging therapy”) in the last weeks before competitions. Consequently, after ceasing administration of the readily detectable synthetic steroids, athletes of both sexes were routinely injected with testosterone esters of various fatty acid chain lengths. This precompetition program of repeated intramuscular injections of testosterone esters had by then become a common procedure in several countries. This is also evident from the analysis by the West German, IOC-approved Doping Control Laboratory in Cologne of the unused aliquots of urine samples (“B samples”) taken during the 1980 Olympic Games in Moscow: Even at the games, 7.1% of all female urine samples were still positive for testosterone doping, as revealed by a testosterone:epitestosterone (T:E) ratio >6 ([62](javascript:;)), including samples from athletes in events such as fencing, in which androgenic doping is uncommon. Only since 1982, when doping tests for testosterone were introduced by the Medical Commission of the IOC for the 1984 Olympic Games (in fact, it had been announced by the International Athletics Association earlier) have T:E values >6 become rare findings.
In the GDR sports system, however, this “bridging” by testosterone injections was used through the late 1980s, as has been documented for hundreds of male and female GDR athletes. [Fig. 4](javascript:
, for example, shows the pattern of testosterone bridging in 1981–1984 for athletes in several events. Moreover, several male and female athletes used testosterone ester injections throughout the season, in addition to their Oral-Turinabol and mestanolone tablets. Consequently, virilizing side effects in female GDR athletes were frequent and pronounced. Höppner reported the following to the Stasi on August 30, 1979: “Now as ever before testosterone is injected in irresponsible amounts, and this even at competitions where it does not matter so much that spectacular records are achieved.”
When it became clear in 1981 and 1982 that the IOC would introduce doping tests for exogenous testosterone, Höppner, who was a member of the respective international commissions, reported this threat to GDR success in international sports to the governmental and sports authorities. A symposium to face this problem was held in Leipzig on June 24, 1981, which included six professors and a senior researcher and physician. The protocol and copies of some lectures of this and other similar meetings have been saved ([42](javascript:;)) and published in total elsewhere ([10](javascript:;))([11](javascript:;)).
At the 1981 meeting, the following was proposed and agreed to:
- to determine alternatives to the exogenous application of testosterone,
- to replace testosterone by its precursor, androstenedione, various forms of dihydrotestosterone, dihydroandrostenedione, or dehydroepiandrosterone (DHEA), and
- to administer testosterone as well as dihydrotestosterone by nasal spray,[4](javascript:
In the ensuing years nasal spray preparations containing testosterone or androstenedione were indeed developed in collaboration with VEB Jenapharm, tested, and used in top athletes—some of whom did not like this mode of application (as described by some athletes; see refs. ([11](javascript:;))([12](javascript:;))([32](javascript:;))).
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Do you have an LFT comparison per mg/day comparison for the two?
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What is LFT?
I wondered about this. I hyperlinked on the term above but i guess you cant see it on the phone version of the site.
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I’m not sure. There are a few spots in post 22 I think that look like they didn’t copy over that well. They look like this:
Not sure if that’s what you are talking about. I did look through the PDF that has Ben Johnson in it, and found the dosage per year thing pretty interesting.
If you run it again even a few of these would give you decent idea. Oxandrolone much easier on the liver.
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Just go to the source document:
I’m not repairing all that.
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I’ve never done liver labs on orals TBH. I do bloods during cruise. Alt and AST are generally in range but top of range or a little higher (1-5 points above).
I’m guessing tbol is worse in the liver.
I haven’t confirmed this hypothesis, but I’m thinking var processed by the kidneys mostly, where tbol is mostly processed by the liver. I’d guess then that var will be harder on the kidneys and tbol harder on the liver. If I’m picking which organ I’m going to stress, I pick liver. It seems to have better recovery abilities. Maybe this logic doesn’t play out though?
I get a 403 restricted warning on the last post when I click.
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That’s too bad. Good read.
https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/cpt1973145862
Fair point. Run your CMP14 and get your eGFR estimate as well so you can compare liver vs kidney impact head to head. I didn’t see any impact on my kidney with 50 mg/day for a few weeks. Slight elevation in ALT/AST.
New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race | NEJM
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