Since it seems some of you don’t actually want a discussion on the subject and refer all of your knowledge to direct quotes from authors with no references, I guess we can start with:
Iacono G, Cavataio F, Montalto G, et al. Intolerance of cow’s milk and chronic constipation in children. N Engl J Med 1998 Oct 15; 339:1100-4.
concluding: [quote]Soy milk decreased chronic constipation in young children[/quote]
According to Mark R. Corkins, MD, CNSP, SPR, at the 2005 Annual Meeting of the Pediatric Academic Societies in Washington:
[quote]studies in humans show that nutrition and growth are equivalent to cow’s milk-based formulas. A reproductive study of more than 800 adolescents who received soy-based formulas found no differences, and IQ studies in 9- and 10-year-olds found no differences between those who were given soy-based formulas. Vaccine response was also no different in children who received soy-based formulas.
According to Corkins, long-chain polyunsaturated fatty acids (LCPUFAs) are essential to the development of the infant’s nervous system. LCPUFAs are naturally found in breast milk, and some formulas contain supplements, although Corkins said that breast milk is the best option for supplying LCPUFAs to the infant[/quote]
Centre for the Evaluation of Risks to Human Reproduction. DRAFT NTP-CERHR EXPERT PANEL REPORT on the REPRODUCTIVE and DEVELOPMENTAL TOXICITY of SOY FORMULA. January 2006.
and
Strom BL, Schinnar R, Ziegler EE et al. Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood. JAMA. 2001 Aug 15;286(7):807-14.
states:
[quote]Studies in children
"Giampietro et al. (ref 156 in full text of report, freely available) … conducted a retrospective study to determine the hormonal and metabolic effects of long-term feeding of soy formula in children. The study population consisted of 48 children age 7-96 months who had been fed soy formula exclusively for at least 6 months…
In terms of results, the authors found:
“Height and weight were in the normal range for all children, and there were no differences between soy-fed and control groups. No signs of precocious puberty in girls or of gynecomastia in boys were found. All 17a-estradiol concentrations were below the method detection limit of 20 pg/mL. No significant differences were seen in serum or urinary measurements, except that soyfed infants had significantly lower urinary calcium and significant higher urinary phosphate in children 7-24 months old compared to control children.
The authors concluded that long-term feeding of soy formula in infants did not produce estrogenlike hormonal effects. They suggested that their findings confirm the theory that phytoestrogens have a low affinity for ERs and therefore produce only weak biologic effects…” [/quote]
It also states:
[quote]n addition, Strom et al examined exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in adults:
“DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study conducted from March to August 1999 among adults aged 20 to 34 years who, as infants, participated during 1965-1978 in controlled feeding studies conducted at the University of Iowa, Iowa City (248 were fed soy formula and 563 were fed cow milk formula during infancy). MAIN OUTCOME MEASURES: Self-reported pubertal maturation, menstrual and reproductive history, height and usual weight, and current health, compared based on type of formula exposure during infancy. RESULTS: No statistically significant differences were observed between groups in either women or men for more than 30 outcomes.”
“CONCLUSIONS: Exposure to soy formula does not appear to lead to different general health or reproductive outcomes than exposure to cow milk formula. Although the few positive findings should be explored in future studies, our findings are reassuring about the safety of infant soy formula.” [/quote]
As far as adults:
[quote]Studies in adults
“Studies in men used dietary additions of tofu (198), soy milk (201), or a soy supplement (200). Interventions were applied for 1 or 2 months. These studies found no effect of the intervention on serum testosterone or 17a-estradiol,…Mitchell et al. (200) found no effect of a daily soy supplement with 40 mg isoflavones on testicular volume or semen analysis parameters after 2 months of treatment. There were only 15 subjects in this study.” [/quote]
Bottom line, I am not saying there is no risk. I am saying fearmongering is a little uncalled for.