If your diet and exercise continues and you don’t go crazy with eating garbage then yes. You may gain little back once you stop as your insulin sensitivity will change but with good habits you’ll be fine. The key is keeping the dose low enough to be effective and still being able to eat tha cals you want to eat. If you take too much and suppress your appetite too much you’ll prob be ravenous when you stop. For pure fat loss I would take retatrutide first then tirzepatide then semaglutide. That for me was the order of mose effective to least effective. Your mileage may vary.
GLP-1s only work while you take them. They suppress ghrelin and other appetite regulating hormones, but when you stop, those hormones often rebound to levels higher than before treatment. This is why many doctors keep patients on long-term maintenance doses. It is a money grab.
GLP-1s drastically reduce caloric intake, which lowers your RMR as your body adapts to fewer calories. Muscle loss also reduces metabolism and RMR, and this isn’t just due to lack of protein as many try to push.
Weight regain after stopping will happen. Some studies have shown 2/3, 50%, and 80% of lost weight comes back. How can anyone expect to suppress their appetite to the point of eating a fraction of their normal intake, then return to “normal” eating without consequences when stopping the drug?
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@OTay
I agree with some of your statements but from personal experience with a person who has always trained hard, done cardio and had a good diet you will not lose muscle unless you are sedentary. You will not gain very much weight back if you don’t go crazy with the drug and binge when you come off and rebound.
Insulin sensitivity will decrease once coming off which may put a couple pounds on as your body isn’t as efficient at processing glucose but that’s about it.
Bottom line is taking a glp1 while living a lifestyle that most of us on here live will give give you issues once you stop unless you take too much and/or don’t train and eat properly when you come off.
I have tried sema, tirzep and retat and have not gained more than a couple lbs when I came off.
Aren’t you in the States? I don’t know how to access it.
Yes
My email is in my profile.
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Um, I’m going to show myself as being really dense here, but I don’t see it.
You have to hit the expand on the right.
I’ll send you an email shortly.
Ah! That explains it.
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Where can you get retatruride? Not FDA approved yet
I’m considering Tirzepatide now. I’m on BMI 29 rn, And I’ve also heard that it works wonders with gut fat which is harsh to impossible to eliminate with any form of diet or exercising.
We really don’t talk sources on here.
Fat loss is not selective. You lose it where you lose it. Tirzepatide is also good for fat loss. I’ve used both with great results.
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From what I read, I’m not talking about “abdominal” fat, but “visceral fat”. Theoretically the visceral fat is the fat between the guts. And this fat is not something that it seems to be removed simply by reducing the total body fat. It seems to be a persistent fat, that even some people with 10 or 12% body fat, still could hold a ton of visceral fat.
And theoretically again, these medicines help, for some reason reducing this gut fat.
Maybe is bullshit, not gonna lie. Here is some info I found about the topic (minute 10.45)
We all lose fat differently. Only way to find out how you lose fat is to do it. Both retatrutide and tirzepatide are great tools to help lose bodyfat.
What are you currently doing and what are your stats?
Do you have a training/diet log?
In my country you can only get a legal recipe for tirzepatide with a BMI over 30 or if you have a bad condition with BMI over 27.
In my case I’m currently in 29 so I think I could manage to get a tirzepatide recipe. For retatrutide I don’t really have a way to get this for now.
Go with that then. Start at 2mg. It works great. Make sure to follow dosing recs. If your feeling nauseous you can split the injection dose.
In my country it starts at 2.5mg then 5mg and then it jumps to 10mg (obviously you can take one 2.5 and 5 for 7.5mg)
The problem is the money.
My idea was to start on 2.5 for 1 or 2 months and then move into 5mg and stay there for the rest 4-5 months. More than 5mg will be hard to afford ngl.
But I don’t really want to reduce overall fat. I don’t have any rush to reduce fat. Personally I wanted to take it for that visceral fat thing that I’m not even sure if its true or if its bullshit. If you see some minutes of video you will hear what “theoretical” benefits he talks about, which maybe are overhyped.
2.5mg is fine. You don’t have to move up in dose if it is still working.
You can’t spot reduce fat. Don’t care what anyone says. It just doesn’t work like that. Typically visceral fat will stick around until your overall BF level is reduced.
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Its weird because once you get say, 12% body fat, noone will give you a recipe of this so if it could be any true that visceral fat could be reduced for health purposes, it won’t be accessible only via alt-markets.
?. Not really sure what your saying.
I think, you can’t get a prescription if you are lean, even if you have visceral fat.
If your trully 12% why would you need it?