You don’t need to use dmso to absorb pgf-2 through the skin. The molecular weight of pgf-2 is low enough to pass through the skin on its own. The only question is would enough pgf-2 get to the fat cells before it is taken up into the bloodstream.
Sure you can use a 22 gauge needle to inject pgf-2 but why would you want to when you can use a 27 gauge needle? 27 gauge needles are used to inject insulin. You know those 1 cc syringes that come prepackaged with the orange cap over the needle.
Finally before you use pgf-2 try to find out as much as you can about this prostaglandin before you use it.
I don’t think I would use pgf 2. I used it twice not only did my biceps hurt for hours and I mean intense, don’t move, muscle cramp pain on top of that I dumped for a lengthy time. No telling what it would do to the muscles in your face.