Labs: Low Red Blood Cell and High Creatinine

Curious as to your guys thoughts on my labs. I was feeling symptoms of low t through 2020. Brain fog, no energy, no morning wood, and worst of all NO MOTIVATION to do anything in life which is not me. I had two knee surgeries and a back injury that side lined me from lifting and I ate my feelings and put on 45-50lbs of fat. (I know this didn’t help). That led me to start getting bloodwork. At that time natural my numbers were:

Total T=394
Free T=12.9
SHBG=22.9
Prolactin=13.0
TSH=.882
T4=1.4
FSH=2.3
LH=6.7

In 2021, I started on Clomid for 3 months under an Endo. It bumped my test to 525 but free test stayed around the same. Most of my symptoms were still there, but bc of my test numbers he obviously wouldn’t do testosterone treatments. I have continued on Enclomiphine since and got a hold of some Semaglutide. I needed something to get a win, and Semaglutide did the trick. I was finally able to be disciplined and incorporate healthy eating patterns again. I’ve since went from 250lbs to 207.5 as of this morning. I feel about 75-80% of my old self mentally again. Anyways, here are my current labs.





Things I’d love your expertises on:

-My total test has increased but free test has stayed low?
-Creatinine has always been at the high end (1.3-1.4) but now it has climbed to 1.59. They did an ultrasound of my kidneys last year to be safe and everything was perfect. I stopped taking creatine for 1 month before this lab. I do lift weights 5x a week. I drink 80-100oz water everyday along with one sugar free Monster. Milk thistle also hasn’t changed this number.
-My red blood cells are always low, along with the MCH/MCV being slightly off. I get plenty of b vitamins through food and supplementation. Since test raises increases rbc/hematocrit, would this help with energy per se?
-Estadiol is elevated ever since using Clomid/Enclomiphine. Is this because I’m 20lb over weight or my body likely just high estrogenic?

If you are carrying a good deal of muscle mass and workout a ton slightly elevated creatinine levels aren’t uncommon

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your SHBG raised, which eats up more of your FT. Your TT is elevated because of the SHBG increase.

Higher muscle mass and heavy weight training will keep this number high. mine is over the reference range.

doubt it would affect energy, but it can help increase cardio capacity a bit.

It’s because you’re on clomid. Yes, fat does increase estrogen, but I’d point this increase at clomid before anything else.

Do you know the reference range here? high prolactin can be problematic and related to estrogen.

EDIT

How much vitamin B6, specifically? B6/P5P is shown to reduce prolactin, which can be a strong contributing factor to your lack of motivation.

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Should cap out at 15ng/ml since this appears to be labcorp.

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@blshaw @Andrewgen_Receptors it seems to say 2-18 are mens reference ranges. They have not tested my prolactin in almost 3 years.

Im curious if I should try and come off the Clomid and see if my natural levels will stay the same. Thoughts? It just feels good to feel mentally normal again and lifting/seeing results.

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Your T levels are likely to reduce by doing this, but I think you are a likely candidate for TRT. Only way to tell would be to stop clomid and test bloodwork.

FWIW, TRT is not far off from the cycle you proposed not long ago, and would result in very similar effects - but in a safer manner.

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Yeah that’s what I’m trying to consider-my best course of action. You guys motivated me to drop more fat before starting so I’m going to hammer out my cut for 4-8 weeks and re-evaluate from there.

I have all the products to go either way TRT/cycle.

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Exactly what my doctor said too. My creatinine was elevated even without creatine. My kidney was fine as well

@sandos thanks for the feedback. They sounded so concerned that it worried me!