New here, not sure this is in the right place, so if not, please be nice!
52 yo male 6’3” 212lb. Started TRT 3 years ago b/c T was in low 300’s and my libido was getting low. Also, had a vericocele in my left testicle. Not worried about fertility, have 4 kids and am done!
What I take: Inject 1 MG weekly test cyprionate, 1 tab of anastrazole on same day, 1 capsule of enclomiphine 3x week (MWF).
Recently having difficulty reaching climax with my wife. It happens usually, it just takes a long time.
There are some big red flags here. First it’s pointless to take enclomiphine while on exogenous testosterone and if anything will take away benefits of TRT.
Enclomiphine lacks the estrogenic effects that clomid possesses, so you may not be getting the full effects of estrogen, one of the main driver of effects on TRT.
There’s no such thing a 1 mg of Test, it would be nearly impossible to inject 1 mg.
Most men on replacement doses of testosterone do not need anastrozole.
Whoever is providing you with your current regimen doesn’t have any idea how to manage male hormones.
You have too many moving parts to pinpoint what is causing your issues, it’s probably both the anastrozole and the enclomiphine.
You need to learn to communicate your dosages properly. I’m sure you meant 1ml which is still a volume and not the proper way to communicate your protocol. Look at your vial and see what the concentration is… likely 200mg/ml. Then if you’re taking 1ml it would be 200mg per week. Is it that?
Hey! Thanks for the reply. Sorry about the incorrect info. I take 1ML of testosterone 150mg/ml concentration 1x week.
When I originally started this I was taking HCG instead of enclomiphene, but it got taken away, so I was recommended Clomid, but I had read that it caused mood issues and other effects that I don’t remember off the top of my head. So enclomiphene 25mg 3x/week (MWF) was next offering.
It’s seemed to be fine, other than some times being difficult to climax. Recently, though this problem has been more common.
The Anastrozole dose is .5 mg 1x week. My understanding for why I’m taking this is to reduce the estrogen that can cause things like gynomastia.
I’m extremely interested in your thoughts about Clomid instead of Enclomiphene and not taking Anastrozole.
My original test level was low 300s and last time blood was tested it was 927. Estradiol was 34, sex hormone binding globulin was 22 and tsh was 2.32.
This was done in August, so I’m sure it’s changed.
I don’t know if this matters, but I donate blood every 55 days or so.
Let me know if this is more helpful and if you need more info.
Prolactin, high IGF-1, DHT, testosterone and estrogen all contribute to gynecomastia, which is a genetic condition. Gynecomastia is rare around these forums, you don’t hear about it very much.
If this is what your doctor told you, it’s a pretty lame excuse to start anastrozole.
Clomid has a horrible side effects profile! Again it’s pointless to take Clomid while on exogenous testosterone. This T-Mill is just trying to sell you as much as they can get away with even though it’s providing no benefit.
Be careful, you risk crashing your ferritin with repeated blood donations!
Libido is strong, boners usually strong, yesterday not the usual, and couldn’t finish with wife.This is why I came to this site to get some info.
On a side note, when I started my scrotum shrunk significantly and has stayed small. There are times when it’s more like it used to be but usually small. I believe this is normal?
Donate blood because I’ve been told that it’s beneficial while on trt because body producing more rbc and too much can be a strain on the heart.
I feel fine on 150/week besides what I’m experiencing in bed.
Are you saying it would be best to just take the 150MG and cut out the anastrazole and enclomiphine?
Regarding my body comp I am in good shape but store fat in my belly area. I saw on these forums that low estrogen can cause that? I AM 52 so I just figured I needed to exercise more to burn it. Are you saying it could be easier w/o the anastrazole, and even the emclomiphine?
You’re bleed part of the main benefit to TRT. Just ask Lance Armstrong!
My hematocrit is 51% on TRT and had it as high as 57% without problems.
With a secondary erythrocytosis there is an increase in blood volume which enlarges the vascular bed, decreases peripheral resistance and increases cardiac output. Therefore, in a secondary erythrocytosis optimal oxygen transport with increased blood volume occurs at a higher hematocrit value than with a normal blood volume. A moderate increase in hematocrit may be beneficial despite the increased viscosity.
There are over 80 million people that live higher than 2,500 meters and they develop a secondary erythrocytosis. Men in parts of Bolivia for instance have a normal range of HCT from 45-61%. These men are not at an increased risk of thrombotic events nor do they have to undergo phlebotomies to manage their hematocrit.
Yes, dial-in on TRT in isolation. Right now you have too many moving parts.
Also, some men get more side effects injecting once weekly. Splitting up your shots can alleviate side effects.
Absolutely! I took an AI once and my estrogen drop down to 12 and I noticed a lot more belly fat suddenly appeared within two weeks of taking it. The belly fat went away after ceasing the AI.
My Hematocrit in August was 46.1 which shows in standard range and the clinic’s range with 50+ being out of range. What do you mean about Lance Armstrong? Sorry if I’m ignorant. I know he got in trouble for doping but don’t really know what that means.
I don’t seem to have issues with the 1 injection/weekly but would you recommend 75mg on Mondays and Thursdays? And you think this would help with the sex?
That’s what I thought, if you don’t like those ranges, go to a different lab company with a higher cutoff, 51, 52 or 54% cutoff.
I used to have them hematocrit of 55% on TRT and my doctors are we’re never concerned, so long as I had no symptoms.
Your doctors are basing all their decisions on lab ranges, and don’t really know how to interpret the lab values. For them it’s stupid simple, no thought process, no critical thinking, just keep you in range and play it safe.
The guidelines for TRT is <54%, even this number is arbitrary.
Glenn Cunningham, the guy who wrote the Endocrine Society guidelines for hematocrit, stated when ask at a medical conference, where did you come up with the 54% cut off for hematocrit. His response was, we actually don’t have much data to say anything but we had to pick a number and it seemed like a reasonable number.
You most likely have low ferritin levels from repeated blood donations.
Out of curiosity, how do you know so much about all this? I’ve tried to find info on the web and really just usually end up with the same stuff I’ve been told.
To be completely clear about myself, my desire is to stay strong into old age. I see my father and father-in-law getting super weak now and yes, they have not been active much since they were in their 50s so I am continuing to work out and do cardio regularly, but I think having testosterone at a good level into older age will be beneficial. I’m guessing since you’re on this site you feel the same way? I don’t know your age but your thinking is probably the same as mine?
ExcelMale has dozens of up to date studies posted almost daily, linking medical conferences for all to watch and learn.
This is what multiple studies show. A few weeks ago, a 79-year-old came into EM and said he had been on TRT for 25 years, and that he doesn’t have the aches and pains of other men his age.
Free T in the top 25% percentile equals a 53% reduced chance of prostate cancer and reoccurrence. A 30% decreased risk of heart attacks, strokes, and risk of dying.
For women after menopause, estrogen therapy reduces risk of stroke by 62%!