My workout times are either 12:00 noon or 7:00 PM. So I could shoot the 100mcg anytime I want. I forgot that you were also shooting before bed. So I guess this looks like a good protocol as it obviously worked well for yourself. I hope all goes well with the taper.
I woke up this morning and noticed that my nipples were itchy and quite red,i felt around for a lump and as i gently squeezed liquid came darting out…SHITT!!this has never happened to me before. ive read around and found out these could be signs of high prolactin levels…any input on this?
Damn Sota that’s crazy! Galactorrhea from high prolactin is supposed to be very rare in men, if that’s in fact what is happening.
Any sexual side effects?
If high prolactin is the culprit than cabergoline is supposedly the way to go. It’s a dopamine agonist that prohibits the release of prolactin from the pituitary, and at least anecdotally, is very effective.
If it’s not galactorrhea, than I have no clue what could be the cause.
Did the liquid resemble breast milk, or was it more like pus?
Damn bro! Your still not running any aas right?
On a side note I have narrowed down what I plan to do.
- 100mcg a day pegMGF bilaterally in the morning in the intended muscle group. (I workout in the evening). Possibly excluding off days.
OR
- 250mcg 2x a week bilaterally hitting a different muscle group each time.
I will also be running 250mcg a day ghrp-6 split into two injections. 150mcg post workout and 100 before bed. I want to start the dosage somewhat low and increase as needed.
Any advice appreciated as this is my first run with both ghrp and pegMGF.
[quote]sota123 wrote:
I woke up this morning and noticed that my nipples were itchy and quite red,i felt around for a lump and as i gently squeezed liquid came darting out…SHITT!!this has never happened to me before. ive read around and found out these could be signs of high prolactin levels…any input on this?[/quote]
Was this the first day you noticed the nipple tenderness, and then instant liquid? Considering you have been off AAS for several months it would almost have to be associated with the GHRP-6 use. Though I have not read anything similar to this in any of the previous logs I came across.
I am really curious as to if this came about all of a sudden or if it progressed slowly. Please keep us updated.
[quote]arthursaxon wrote:
Damn Sota that’s crazy! Galactorrhea from high prolactin is supposed to be very rare in men, if that’s in fact what is happening.
Any sexual side effects?
If high prolactin is the culprit than cabergoline is supposedly the way to go. It’s a dopamine agonist that prohibits the release of prolactin from the pituitary, and at least anecdotally, is very effective.
If it’s not galactorrhea, than I have no clue what could be the cause.
Did the liquid resemble breast milk, or was it more like pus?[/quote]
It was a clear liquid with a tint of yellow,no puss, just liquid.I dont have cabergoline on hand and probally wont because it is way to expensive. but i do have bromo left over from a test+tren cycle 1 year ago.Could this be used as an alternative?
[quote]dean12345 wrote:
Damn bro! Your still not running any aas right?
On a side note I have narrowed down what I plan to do.
- 100mcg a day pegMGF bilaterally in the morning in the intended muscle group. (I workout in the evening). Possibly excluding off days.
OR
- 250mcg 2x a week bilaterally hitting a different muscle group each time.
I will also be running 250mcg a day ghrp-6 split into two injections. 150mcg post workout and 100 before bed. I want to start the dosage somewhat low and increase as needed.
Any advice appreciated as this is my first run with both ghrp and pegMGF.[/quote
ya ive been off aas for a few months now.
I favor your first choice rather than the second.As far as the ghrp dose, that pattern worked well for me, but from talking to 2thepain, he seems to have a much higher tolerance than i did so basically your just going to have trial and error the doses untill u find what feels right.
[quote]2thepain wrote:
sota123 wrote:
I woke up this morning and noticed that my nipples were itchy and quite red,i felt around for a lump and as i gently squeezed liquid came darting out…SHITT!!this has never happened to me before. ive read around and found out these could be signs of high prolactin levels…any input on this?
Was this the first day you noticed the nipple tenderness, and then instant liquid? Considering you have been off AAS for several months it would almost have to be associated with the GHRP-6 use. Though I have not read anything similar to this in any of the previous logs I came across.
I am really curious as to if this came about all of a sudden or if it progressed slowly. Please keep us updated.[/quote]
There is no lump or tenderness,they are just itchy and a bit red and liquid is coming out of them. i literally noticed it the second i had woken up almost as if it happened over night.dunno about this.I was running high doses of letrozole towards the end of my aas run, could it possibly be a rebound effect?
I will be taking after pics by the end of this week.Apparently pics are not allowed on the steroid forum. i read that on the cellulits thread when it was asked to show pics.What are the rules to this?
micro update,the past week ive been noticing red scratch like lines on my traps and they keep getting bigger, so i came to the conclusion that they are stretch marks which excites me on the fact that im making shoulder improvements but then again i dont want these to get any deeper.i guess theres nothing i can really do about this, correct?
Bromocriptine should be the next best thing, particularly since you have some on hand! I’d start running it ASAP and see if the symptoms subside.
I haven’t found anything associating GHRP-6 with prolactin, but as it’s a relatively new peptide on the block, who knows. Not sure about the letro rebound theory either.
You’ve certainly had your share of bumps & bruises- it will be very interesting to see if the symptoms you’ve experience arise during the GHRP-6 cycles the few of us on here will be (or are now) running.
Until then it will be hard to distinguish with any certainty what to associate with the peptide and what just happened to coincide with it for you.
Hope the issue clears up quickly for you, keep us posted.
Art
[quote]sota123 wrote:
I will be taking after pics by the end of this week.Apparently pics are not allowed on the steroid forum. i read that on the cellulits thread when it was asked to show pics.What are the rules to this?
micro update,the past week ive been noticing red scratch like lines on my traps and they keep getting bigger, so i came to the conclusion that they are stretch marks which excites me on the fact that im making shoulder improvements but then again i dont want these to get any deeper.i guess theres nothing i can really do about this, correct?[/quote]
Bushy just recently ran a thread with pictures of him in it, just no aas pictures I assume.
If I were to guess I would say a letro rebound. However considering how new GHRP-6 is there is probably a lot still unknown. Just to be safe I just ordered myself a bottle of caber.
Im doing reaserach for my upcoming aas cut cycle.
I think im going to keep it fairly simple, 12 weeks Test prop, Mast. prop,winn/var combo,Clen/eca.
Ive been looking into pgcl,ive read several logs and most of them just sound to good to be true its very tempting but the sides just seem unrealistic,explosive diahrea just doesnt sound to pleasant to me.As of now im just still trying to figure out which of my sources to use, which is just really irritating me right now.
The general consensus on PGCL is that the weight loss is from the laxative effect, while the site growth is from the increased inflammation the drug causes. Doesn’t exactly sound like much of a wonder drug to me, but who knows.
By the way, I would assume that it was the GHRP-6 that contributed to the prolactin increase, and not the Letro. A number of studies have shown that GHRP-6 DOES increase prolactin, although the administration of Bromocriptine does indeed negate these effects.
If I can find the study again I’ll post it. Can’t imagine it should be too hard to find.
Why use prop (short ester) on long cycle?
About PGCL: i have researched it too, i think it is a lot hyper extimate. And the weight loss is from laxative as Schmazz says… not so wonderfull. I’ll stick on winny+ephedra+clen+test+diet 
[quote]cadav wrote:
Why use prop (short ester) on long cycle?
About PGCL: i have researched it too, i think it is a lot hyper extimate. And the weight loss is from laxative as Schmazz says… not so wonderfull. I’ll stick on winny+ephedra+clen+test+diet ;)[/quote]
Sorry, i was really brief, prop is going to be ran 1-8 and the remainder will be pct with igf,im just really not sure yet i have to figure out first what i can get my hands on be fore i go further into planning.I wouldnt cut with enth or cyp,i like prop, i get to bloated with long estered tests.and as of now PGCL is an official NO for me.
[quote]Schmazz wrote:
By the way, I would assume that it was the GHRP-6 that contributed to the prolactin increase, and not the Letro. A number of studies have shown that GHRP-6 DOES increase prolactin, although the administration of Bromocriptine does indeed negate these effects.
If I can find the study again I’ll post it. Can’t imagine it should be too hard to find.[/quote]
I you find that id really like to read it.ive looked around but can really find anything on that topic.
[quote]sota123 wrote:
Schmazz wrote:
By the way, I would assume that it was the GHRP-6 that contributed to the prolactin increase, and not the Letro. A number of studies have shown that GHRP-6 DOES increase prolactin, although the administration of Bromocriptine does indeed negate these effects.
If I can find the study again I’ll post it. Can’t imagine it should be too hard to find.
I you find that id really like to read it.ive looked around but can really find anything on that topic.
[/quote]
[i]
1: Clin Endocrinol (Oxf). 1996 Jan;44(1):67-71.
Hexarelin, a synthetic growth hormone releasing peptide, stimulates prolactin
secretion in acromegalic but not in hyperprolactinaemic patients.
Ciccarelli E, Grottoli S, Razzore P, Gianotti L, Arvat E, Deghenghi R, Camanni G,
Ghigo E.
Department of Clinical Pathophysiology, University of Turin, Italy.
OBJECTIVE: In man, new synthetic peptides such as hexarelin have been shown to have a potent and dose dependent GH releasing activity. Furthermore, a significant PRL releasing activity has also been demonstrated, but this has been investigated in less detail. We have therefore evaluated the effect of hexarelin on PRL and GH secretion in patients with active acromegaly or pathological hyperprolactinaemia. DESIGN: Hexarelin (2 micrograms/kg i.v.), a modified derivative of GHRP-6 of the following structure:
His-2-Me-D-Trp-Ala-Trp-D-Phe-Lys-NH2, or placebo, was administered in random order on two separate occasions. PATIENTS: Eight patients with active acromegaly (ACRO, 6 F and 2 M, mean age 61.7 years, range 56-73), 6 with macroadenomas and 2 without radiological signs of tumour, and 6 female patients with pathological hyperprolactinaemia (HPRL, mean age 31.2 years, range 18-47) 5 with microadenomas and 1 with empty sella, were studied. Fourteen normal subjects (NS, 8 F and 6 M, 27.1 years, 24-30) were studied as controls…
CONCLUSIONS: Our data show that the PRL releasing effect of hexarelin is preserved in acromegaly but lost in pathological hyperprolactinaemia. In contrast with acromegaly, the GH releasing effect of hexarelin is also blunted in hyperprolactinaemic patients.These data demonstrate that patients with pathological hyperprolactinaemia are partially refractory to the activity of hexarelin.
2: J Clin Endocrinol Metab. 1993 Dec;77(6):1641-7.
Effects of a prolonged growth hormone (GH)-releasing peptide infusion on
pulsatile GH secretion in normal men.
Jaffe CA, Ho PJ, Demott-Friberg R, Bowers Cy, Barkan AL.
Department of Internal Medicine, Department of Veterans Affairs Medical Center,
Ann Arbor, Michigan.
Bolus injection of the synthetic hexapeptide GH-releasing peptide-6 (GHRP-6) reliably promotes GH secretion. However, desensitization to the GH-releasing effects of GHRP has been shown to occur during short term iv infusion. To determine whether humans would remain responsive to prolonged exposure to GHRP and to study the mechanism of action of GHRP, we compared the effects of a 34-h iv infusion of either GHRP or normal saline on parameters of pulsatile GH concentration in nine healthy young men… There was no change in either GH pulse frequency or interpulse GH concentration. During GHRP infusion, the GH responses to the GHRH
boluses were augmented; however, baseline TSH was lower, and the GH and TSH/PRL responses to GHRP and TRH, respectively, were smaller. We conclude that the pituitary remains sensitive to GHRP during a prolonged GHRP infusion. The mechanisms of the GHRP effect on GH secretion are uncertain, and the possibility that GHRP acts as a functional somatostatin antagonist is discussed. The contrasting effects of GHRP on GH and TSH/PRL secretion could be due to differential effects of GHRP on the pituitary and hypothalamus.
[/i]
Uh…“Kids, don’t try this at home!”
Let me see if I can give this one more try… Here’s my theory:
You said that you used Letro during your PCT. My best guess is that you’re experiencing an estrogen rebound from the letro. GHRP-6’s prolactin release abilities is believed to be mediated by Estrogen (E2) in the study: “these GHRP-6 actions may be modulated by E2 at both hypothalamic and pituitary sites.”
My best guess is that because the prolactin is mediated by E2, and you’re probably on a letro rebound, I’d say you were in the wrong place, at the wrong time, injecting the wrong stuff. You’re E2 levels got high because of the rebound, and this mediated the prolactin release from the GHRP-6.
Now call me crazy - but here’s my idea. Try the Bromo you have, but you may also want to try running an AI with it. If the release of prolactin is TRULY mediated by E2, then an AI would cut back the E2 levels, and thus relieving the mediation of prolactin release by the GHRP-6.
STUDY CITED: http://lib.bioinfo.pl/pmid:9681512