Josht9210's TRT Log - Depersonalization, Panic Disorder, Agoraphobia, Etc

I usually feel as you described in the middle of the 5th week on new protocols, it usually will pass by week 6. A beta blocker might not be a bad idea during protocol changes.

I’m on a beta blocker right now and it brought my blood pressure down to 116/72 down from 150/100.

Which one if you dont mind me asking? I might as well kill 2 birds with one stone if it tackles anxiety.

My bp isnt the worst rn but when i get panicy or tense or work out i really feel it.

How are the side effects? Libido? Fatigue? Tired 24/7?

And do you stay on it 24/7?

Bisoprolol (5mg), generic for Zebeta. It worked immediately. I get rashes and burning in skin on almost all blood pressure medicines, taking pepcid to control skin reactions.

Does it help at all w anxiety? Is there fatigue? Weak erections? Low gym intenisty?

Trying weight the pros and cons. I see the doc in 24 hours so tryna figure this out.

Getting a lot of contradicting statements. Ik I’ll get some side effects but I mainly need; libido, less anxiety, and preferably no insulin sensitivity or whatever i heard bbs cause

Stuck on;
Propanolol, atenolol and clonidine

I am looking for something to be on 24/7…

Doctors said no bueno to b blockers, my bp was normal and pulse was barely up (102)
Really annoyed because I tried to donate couple days ago but my pulse was over 100.

My anxiety has been ridiculous lately, Like I feel “real” again, but anxious lol. It’s really hard to cope with, prior to trt I was just always numb and didn’t really gaf about anything or get bothered by much, good and bad though.

Now I’m just like hyper alert, hyper aware. Still even on my ssri dosage. I yolo tried aromasin 12.5 the other day, didn’t do anything, still anxious af. I’ll try to lower my dosage, its just annoying because I want to be able to blast so I’m trying to trouble shoot this so I can blast now and then… Part of the reason I got on trt was confidence, help with anxiety, libido, depression… so far I’ve only fealt like its bypassed my ssri and made me feel “real” and anxious, which I’m sure I could’ve achieved by coming off my ssri… I know I have a very special and complicated case of anxiety that isn’t just generalized anxiety but I don’t wanna give up…

The only time I escape my anxiety is at the gym but even there I feel weird for pacing back and forth … I’m actually scared to take this girl(shes been waiting a couple weeks) on a date right now because idk how If I’ll end up having a panic attack or anything in this phase.

I’m thinking of treating the anxiety from an anxiety pov and not trt pov from here on, it just sucks though because the trt has def affected it and idk what to do. Have an appointment with neurologist and psychiatrist for anxiety/migraine issues… I’ll see where that leads me, any advice helps guys

Be careful my friend. I read many of the posts and notice you look at every issue you have and blame TRT or make changes to compensate. This makes for hell wirh hormones.

The body needs a dose that works and then you sit on that dose in your blood for a good year. Trt takes many months to produce its beneficial effects. Not all you can feel. After a year you will look back and realize the difference. until then be patient.i know it’s hard once you feel a solution had been found, but you gotta give yourself tome.

I had anxiousness and many do on trt. Fix it wirh your breathing and meditation and don’t look to medication and other external solitons.
Otherwise it wlll constantly be a pain in the ass. I had bad anxiety / anxious behavior starting trt and I handled it by thinking it through and realizing my body has a load of hormones and it’s going through changes. Breathe through and stop trying to think about everything that’s bothering me. Breathe in. Breathe out. Shut the mind off.

BP and etc will be up as your body changes and adapts to trt. It takes time and it might seem to not work, but it is and after a year you will be much better off. If you keep changing doses and adding removing things it’s going to be hell getting this therapy dialed in.

Sure they are real, but I can guarantee you are making things worse by worrying about everything.

Be careful. I’m not trying to put ya down or be rude. I just read your posts from beginning to end (not all but many) and that is what I noticed.

I’ve spoken to so many guys who had rediculous anxiety and they kept changing their doses and prescriptions. Adding this: lowering that and changing frequencies and etc

What was the solution! Simplicity. Give the body what if’s missing and give it time. Focus on the mental aspect of life.

Anyways several took my suggestions and left it alone: blood work showed good levels and there was nothing to change. Months later they are still great. No more crippling anxiety and sleep issues. Before that they were analyzing every blood value, trying this supplement and complaining of this symptom and that symptom.

Just food for thought. Take what you can and leave the rest.

Every time you change your dose it’s like a woman whose hormones fluctuate. Think about that. You want to stabilize your mood yet you keep increasing and decreasing hormones.

Stop thinking about blasting and stuff. Focus on health and what’s in front of you. That stuff shouldn’t even be on your mind man.

Good luck

Thanks, I will try to stick to my perscribed protocol for now, but god this sucks rn. Blasting is so.ething that will always be on my list but I guess I’ll try to stabelize first

Stick to the dose that worked for you.

What’s up with the thyroid? I had serious depression and other mental issues until I fixed it.

Lots of women have anxiety and depression with low thyroid.

I would get that looked at ASAP and not wait and hope.

For guys like me TRT didn’t work until I started thyroid meds t4/t3 armour thyroid.

Good night

Dr saya w defy said my t3 was in perfect range, he didn’t mention my old t4 or tsh. I worry about messing with my t3 and t4 in fear of more anxiety.

How are you holding up man in terms pf anxiety and overallhealth? Is it going into positive outcome? I havent started my journey yet, Iam still waiting for my things.
Would like to ask you aboutthe paininthe chest, I have it no mattet what I do and like agression. No matter what I do I cant shake it off. I can help myself a little by lifting very hard. Have you had it sometimes?

I’m tolerating. I’m really stubborn and gonna make trt work no matter what. Chest pain is on and off but mine is more so from elevated rhr. My bp has been perfect for a while now.

I don’t get aggressive but I am irritable from anxiety.

Looking more into my issues and estrogen may be good for my brain.

I am glad to hear that. Wishing you best of luck. Iam also sick and tired of the fucking anxiety, so I love seeing your progress. Keep us updated.

On the anxiety note, have you tried CBD oil?

I’m sensitive to cannibinoids, my first panic attack was from weed. I won’t touch anything weed related regardless of thc levels.

But yeah I’m so-so, I’ll do whatever it takes though.

Bisoprolol is a cardioselective beta1 adrenergic receptor blocker. More potent mg/mg than atenolol… so I want some…

@josht9210 firstly… nice trap development… good genetics in relation to muscle bellies

Secondly, why did you’re doc say no to a B.B. amoreliating physical sides manifested in part due to anxiety will eliminate (partially) physiologic sides, both reinforce one another like a viscious loop, and breaking said loop is pivotal to quealming overall anxiety

I know meds aren’t always the best answer but a resting pulse of 106 is pretty high (I used to get very anxious at times, and the racing pulse associated with anxiety make it exponentially worse…) I use atenolol now to aid with social interactions/daily anxiety… and the lack of a fast pulse associated with social interaction and whatever occasional bouts of anxiety I get now makes it SOOOO much easier to control… I can just think “this is retarded, what am I worried about”… then I’m no longer anxious anymore… but with the fast pulse I start thinking “well I’m dead”

Thanks @unreal24278 its actually funny how big I was able to get natty at 23.
Only using creatine & arginine for pumps, i was 173 lbs but I def had a lot of waterweight making me look fuller, no pro hormones or sarms or exogenous t. I actually have decent ab insertions, they are symmetrical, my issue is overly large obliques lol

Idk shes not against trt but shes against the fact that I chose trt and now its causing needs for other meds she said. I’m not too concerned, going to a psychologist and nuerologist to see what they know about hppd/visual snow/centeral sensitivity.

Actually learned a lot about centeral sensitivity that I think you could benefit from. Do you ever get head aches or migraines, with or without aura, light sensitivity etc? Usually that sort if preceeds centeral sensitivity syndrome.
Migraines pretty much create a feedback loop that causes white matter scarring in the brain which leads to centeral sensitivity. Apparently drugs like verapamil and topimax can help cut off this feedback loop. Calium channel blockers and sodium channel blockers are often used so I’m sure I’ll get some sort of sympathetic nervious system deregulator. I actually just started Lamotrigine(sodium channel blocker, if it helps it will explain why I always feel over stimulated) after this research, ancedotley used to help with dpdr, migraines, vss, hppd, ptsd etc.

Also very interesting role estrogen plays in neurons. E2 occupies nearly every neuron in the body, this is why people feel like garbage crashing e2. Also why women suffer from migraines after hormonal spikes, pregnancy etc, they actually use oral contraceptives to prevent menstural migraines. Idk this is all very interesting to me because I’ve been sensitive to light ever since mdma and constant tension head aches, usually this preceeded my anxiety/dpdr. I’ll probably be getting propanolol from a psych, but I don’t want it to effect workouts or libido, any advice for dosing schedule? I also believe propanolol can help in aiding with migraines and what not due to breaking the migraine loop involving the constriction of blood in the brain. I’m sure glutamate also plays a role in fibromyalgia, and centeral sensitivity. However usually those disorders are treated with pro gaba medications as opposed to glutamate inhibitors, lots of the meds used are anti siezure meds, benzos, lyrica, etc.

Currently on 200mg of test a week IM ED to prevent spikes. Dropped mast and cream due to massive shedding jesus christ hair all over my sink and just everywhere.

It’s honestly pretty sad, I’ve been taught to become my own therapist by my therapist, now I legit have to become my own doctor and bring in studies to my doctors in order to get the medicine I request for off label usage due to the lack of knowledge of rare diseases.

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I’ll give a detailed reply tomorrow after I finish up working (so probably tomorrow late afternoon/evening.)

I’m relation to you’re insertions, would you say you have a large bone structure? What’s calf size?

Lyrica was awful for me, the cognitive deficits I acquired while on were extreme… I still believe the medication induced residual damage/irreversible neurotoxicity still present today

Benzodiazepines I was never prescribed, aside from perhaps diazepam, most medical professionals are very cautious to prescribe benzodiazepines here (diazepam is like the equivalent of a schedule V drug in the US, thus it’s prescribed somewhat more freely). It does appear to have a lower abuse potential due to longer duration of action, slow(ish) onset and time to peak etc.

The strongest med I was ever/have been prescribed for chronic pain was tapentadol… the strongest medication I ever TOOK to manage chronic pain at the time was Oxycodone. Vigorous Exercise and supraphysiologic concentrations of hormones has gone a long way in relation to helping me manage with day to day life. I don’t use pain meds anymore unless it’s an absolute emergency. In which case I have oxycodone, tapentadol or Dextropropoxyphene (however this one is quite dangerous, therapeutic window is very small but I’ve found it to work better than anything else). I’ve only had to use (in relation to chronic pain flaring up) about three or four times this year

I’m scheduled for a cortisone shot within the subacromial bursa of my shoulder… so that should provide some relief (also have legitimate pathology regarding my joints and connective tissues)

As to you’re predicament being sad, that’s exactly why I started researching medicine in the first place… keep it up, rare and/or uncommon disorders aren’t purposely forgotten about, they just don’t cater to the uniform demographic… just like school, thus the ones with lesser known ailments are typically forgotten as it’s theoretically more practical to treat the 99.9 percent rather than the 0.1, by being you’re own advocate (something I’ve had to learn to do an awful lot throughout my life at this point) you can still make life of adequate quality

You’re situation regarding MDMA is a very unfortunate one, however there are known consequences that may stem from the use of recreational drugs. You made the decision to use them, you had an unfortunate reaction and now you must live to the best or you’re ability with the setbacks you’ve been given

Whilst we don’t have a whole lot of research on MDMA induced neurological/ nervous system imbalance, I imagine as laws loosen up and more research is allowed (as the conservatives die out #jokes) we will have a better understanding and thus a cure

Even the use of cannabis can have fairly dire consequences for a select few (long standing psychosis is debated) but look up cannabinoid hyperemesis syndrome

I’m mesomorph. Always been medium build, also ex wrestler. I don’t have measurements but my calves are also genetically gifted. I will get leg pics soon, my quads are lacking rn, calves have great muscle bellies though.

Yeah I’m hoping the legalization of weed and soon psychadelics will bring more research into the consequences all though im opposed to the use of both. I havent touched a recreational drug in 10 years. Weed was the first drug that induced panic for me. Also had a bad expierence with laughing gas at the dental office at age 12, everything went 2d

I’m actually taking half of the prescribed 5mg dose, I’m getting the same BP numbers I got on the full 5mg dosage. This stuff is powerful mg per mg.

Week 10-11? I’ve lost track… Kind of depressed over the anxiety, can’t seem to figure it out… Gonna try to lower dosage and go subq… Psychiatrist apt on the 3rd and neuro on the 10th… Hoping to get some propanolol for when I decide to do my blasts, hopefully lowering my dose will keep my anxiety at a baseline and allow me to sustain good gains/libido/energy. Kind of bummed at how things have gone, I really put a lot of research and effort into trt and its just turning out to be another thing my body is sensitive too… I can barely drink more than 1 cup of coffee a day and thats pre trt… Sucks man. Kind of been toughing it out and I’m still determined but, been kind of avoidant in person due to my anxiety… Its dumb because its not even racing thoughts or anything, just a feeling of overstimulation. Going to neuro/psych to discuss my cns/anxiety issue but still, sucks.