My doctor has prescribed me to be on Celebrix for two to three months. I would rather not use it for so long so I stopped after three weeks and the pain, inflammation and relate issues are quickly rearing their ugly heads again. Just looking for some guidance from others who have had to use NSAIDs for extended periods of time. Anything one can do to mitigate the side effects?
So far as I know there is no means, while taking the same amount of the same drug, to reduce the increase in cardiovascular risk that these drugs present.
I would see if aspirin and a natural anti-inflammatory approach (for example curcumin, fish oils, and a concentrated phytonutrient source); and if wanting to go beyond this one might add N-acetyl cysteine, glutathione, DHEA, and/or a mushroom extract such as is sold by Mushroom Harvest. I don’t know if each of those added things mentioned really adds anything – the combination certainly seems to help though even though it may be overkill.
Btw these latter points were brought out in an article that BT posted relatively recently. Nice find on his part. I would have used the others anyway but wouldn’t have thought to use the mushroom extract.
Thanks. I am finding inflammation a bigger issue than I thought as of late. I used curcumin for a while but found higher doses (6 caps a day) lead to heart burn. (I have an excess acid issue that I am trying to figure out.) I plan on trying curcumin again, though at low doses.
How much fish oil do you suggest? I did not notice anything on the 4 caps of Flameouts that is recommended?
Where should I go to find “concentrated phytonutrient source); … N-acetyl cysteine, glutathione, DHEA”? Right now, I think over the top might be needed.
How long would to long be for something like Ibuprofen? I have inflammation under my knee and have been taking Ibuprofen for some time now. However, I fear the the cardiovascular risks may be to much, that and I hate the photosensitivity.
Is Curcumin a good alternative to Ibuprofen for inflammation?
[quote]Bill Roberts wrote:
So far as I know there is no means, while taking the same amount of the same drug, to reduce the increase in cardiovascular risk that these drugs present.
I would see if aspirin and a natural anti-inflammatory approach (for example curcumin, fish oils, and a concentrated phytonutrient source); and if wanting to go beyond this one might add N-acetyl cysteine, glutathione, DHEA, and/or a mushroom extract such as is sold by Mushroom Harvest. I don’t know if each of those added things mentioned really adds anything – the combination certainly seems to help though even though it may be overkill.
Btw these latter points were brought out in an article that BT posted relatively recently. Nice find on his part. I would have used the others anyway but wouldn’t have thought to use the mushroom extract.[/quote]
i heard that glutathione supplementation was useless as it cant be absorbed properly? is this not true? everything ive read has said that whey protein and additional NAC is much better for increasing glutathione levels than actual glutathione supplements
It isn’t efficient. As to whether it’s useless I don’t know: I’ve only read the abstract of a study on that and it was not possible to determine from the abstract whether the amount absorbed was essentially zero or was, to use their terms, not “clinically significant.”
It is more efficient to increase amount of cysteine, for example with N-acetyl cysteine.
For that matter if consuming enough whey protein as you mention, there may be no issue of cysteine availability anyway.
I do want to emphasize again that what I wrote above is not optimized: that is to say, I haven’t determined that each thing mentioned adds significantly.
While at this point I still can’t rule out coincidence, on the mushroom extract my experience was that the exact same protocol upon having the mushroom extract added gave a rapid major jump in improvement (of chronic muscle inflammation of certain muscles); running out of it gave a rapid major worsening; and re-introducing gave the improvement again. So of the various things that I listed beyond the proven fish oils, curcumin, and good supply of phytonutrients, my guess is that the mushroom extract may be the most helpful. This would be assuming a situation where immune modulation might help, which might or might not be the case for the OP (no way to tell from the post.)
You’re probably making a good point on the glutathione: the amount of bang for the buck it may be adding could be quite poor.
[quote]xXSeraphimXx wrote:
How long would to long be for something like Ibuprofen? I have inflammation under my knee and have been taking Ibuprofen for some time now. However, I fear the the cardiovascular risks may be to much, that and I hate the photosensitivity.
Is Curcumin a good alternative to Ibuprofen for inflammation?[/quote]
the cardio risk? i’d worry about my kidneys so stay hydrated