Pretty much with slightly more tension in the lats that way. You can’t really uncouple these muscles nor should you really be trying to unless you are a bodybuilder competing at higher levels who needs to specifically bring out a single muscle.
Use both on pull day if you want. Or just use the regular lat pulldown and low row pulley towers - doesn’t really matter all that much unless you are already insanely jacked and lean.
Better yet follow one of the many plans already available for free on this site.
https://www.t-nation.com/training/the-best-damn-workout-plan-for-natural-lifters/
What is your current training history and what is your goals? If you have access to these machines I am going to assume you have access to a gym.