Never put test in the fridge, it will be crystalize.
Ask your doc for Proviron, its better for lowering SHBG.
Patience is key. It takes a couple months (at least) to really feel the benefits of any new protocol. There is usually a little boost early on, followed by a down-turn when your natural production stops, followed by an upturn as levels stabilize. Expect some ups and downs over the first couple months and try not to read too much into every fluctuation.
1 Like
So,I have both of these. It has sweet dick all to do with anything. Having MTHFR also does NOT actually mean that you have 30% effective detox anything.
LOL. An hour later will not have any effect on your skin, or ever actually at that dose. What happened was your T levels elevated because the Enanthate was starting to enter your system and you were at full natural production still. You had a higher free T to work with.
You are a mental case. Stop obsessing. Enanthate takes at most a couple of HOURS to start working, it takes 6 weeks to become stable. At 2-3 weeks your natural production will die off and you test levels will drop to only what the Enanthate is providing.
So, doctors prescribe higher volumes of test to lower SHBG, becauseā¦higher levels of androgens lower SHBG. Lower levels of androgens raise SHBG. Thatās how it works in normal function, they live in balance and the body uses SHBG to warehouse androgens. In your case, something else is wrong, and you may or may not figure out what it is. Itās not mercury, I promise. It also has absolutely nothing to do with the MTHFR gene mutation. That would simply result in you being intolerant of folic acid and needing methylated versions (maybe, not always) of certain things like Folate. It means your ability to perform the methylation cycle internally is hampered, but no one can actually apply a specific percentage to how much as the mutation affects each individual to a slightly varying degree.
1 Like
I donāt know who āHeā is, but Iām guessing heās not a real doctor. Starting with the goofy name given to a mix of drugs and supplements in an attempt to mystify the process, Tamoxifen will not do anything for your SHBG, but is effective if you have gyno or breast cancer. Donāt take Vitamin D without knowing your actual level and if you need it, it can actually do you harm. And the HCG is an LH analog that stimulates natural production of the testes - not well tolerated by everyone.
1 Like
@dlsmith - This makes sense, thanks for the input thatās really helpful. Iām new to this as you can tell.
@hardartery - Well, in my case it did have something to do with a sharp decline in health, as detoxing + methylfolate + methylB12 did sort out 80% of my issues. You are right in the respect that it doesnāt absolutely mean that will happen in all cases, but if you have it and you get problems, it would be sensible to look at the methylation cycle.
I agree it may not be related to these low test issues, but it did occur around the same time as the above, and I have spoken with people who say SHBG could have something to do with high levels of toxins. Who knows for sure, but what Iām trying to do here is gather as many data points as possible. To try and figure this out. Iām certainly not going to do that by doing nothing. If you think that is mental, then you are welcome to think that. But itās served me well in the past. Thanks for the comments on the other points, all good to know and much more enlightening than the doctor Iām speaking with. I fully agree it sounds weird. He is a āproperā doctor from MaximumClinic but thatās doesnāt mean anything unless the protocol is sound.
@mhmtali Thanks, thatās the second person saying use proviron, been reading about it and looks promising. Do you do proviron with test, or on itās own? What would you think is the best way forward considering I have already done 2 injections of test?
This I believe. I doubt the detox had more than a positive mental effect. Donāt take that the wrong way, mental is important. It has a huge effect on how we feel and recover from things, but it is just that - mental. Your SHBG absolutely is indicative of a problem, I just donāt think that youāve found the cause yet and the drug/supplement cocktail is great way of adding a stack of variables to the situation all at once, making it impossible to know what actually did or did not do what.
Proviron is probably a great choice, just know that it IS going to be suppressive of your natural production and would probably be better if used with some dose of testosterone in combination,
Lol. I did have a mercury filling removed without protection was breathing mercury vapor for 45 mins. I can assure you detoxing did have an effect. My hair, blood and skin tested high for it, I had all the symptoms of mercury toxicity and the chelating agents they use (EDTA, ALA, cilantro etc) had profound effects on my health (both positive and negative over different time frames), and you can literally test your piss when the mercury comes out. I still canāt take more than 6mg of ALA every 3 hours without aggravation and the only thing that ALA does in that doses and frequency is chelate metals. The effects are physical as well, ectopic heart beats which have been measured and recorded with FibriCheck, muscle tremors. Iād be amazed if that was all in my head. But itās a remote possibility. Nothing at this stage of my life would surprise me.
Yea adding another stack of variables I can see being an issue. Have zero intention to do that stack he suggested. Spoke with him today, agreed to just do test at 200mg a week for 8 weeks and see how that works. Proviron it seems canāt be done long term, but maybe will cycle it depending on the results.
Hoping this works, if not then itās off to the monastery.
Here at the updated labs if anyone can make any recommendations:
Blood work prior to starting T + HCG (the original posted blood numbers were 3 months before starting)
SHBG: 77 (normal range 13.5 - 71.4)
Test: 1110 (normal range 240 - 871)
Free: 14.70 (1.3%) (normal range 5.71 - 18.74)
E2: 26 (normal range 11 - 44)
After 4.5 weeks
SHBG: 69.9 (normal range 13.5 - 71.4)
Test: 2163 (normal range 240 - 871)
Free: 41.20 (free as a percentage 1.9%) (normal range 5.71 - 18.74)
E2: 45 (normal range 11 - 44)
Would say things have improved, but not where I was expecting.
@traveling-man I guess this is more complex than I originally thought it would be
1 Like
Add what the normal ranges are
Done.
Were you ever on finasteride? Even once?
@samguy19 Never
Any else have any other idea what could be going on here? Is the test likley to go down to a normal range? Can you continue TRT at those levels? What are the next steps?
@systemlord @enackers Any idea bros?
Whatās the question again?
How do you feel?
Are you taking biotin?
I couldnāt continue treatment at these levels, I think the question can only be answer by you, any negative symptoms?
@systemlord @ncsugrad2002 Yea taking biotin in a b-complex, 60mg.
Okay, so no negative side effects, apart from a little water retention. So what is the normal protocol (next step) for this situation? Stop, take a break, change dose, drop HCG? How long can you continue with 2000+ T levels before bad stuff starts happening? How much time do I have to see what happens? Any pointers would be great. Thanks 
Iād just drop the HCG and things should come down on their own. That is, assuming you felt fine before you added HCG in the first place
People do it for years, decades even.
It isnāt this OMG cataclysmic event because youāre over the normal range. Iāve been at 1500+ for the better part of a year now and my blood pressure and HCT are actually lower than they were pre TRT. Iām not saying you should necessarily stay where youāre at if you donāt need levels that high to feel normal. Iād probably drop the HCG first and see where you settle out at. If you still feel fine at that point, then stay there. If you start feeling worse as levels decline, Iād still leave out the HCG and bump your T does up some to get your levels back up to whatever it takes to get rid fo any lingering symptoms, whatever those might be.
1 Like
Biotin should be suspended a week before doing blood tests, because it interferes with the hormonal results.
I also would have tried Proviron before committing to TRT for life. It has shown a great ability to bind to SHBG, along with a really low hepatoxicity, so that could have been your silver bullet.
@appassionato I do have a box of it, but you canāt use proviron long term. I will give it try however.
In my head I was like Iāll try it for 6 weeks (a normal steroid cycle) and come off if the results are bad. Loads of mixed results here, so at worst I figured would help drop some body fat.