Taken From: http://www.newhope.com/nutritionsciencenews/nsn_backs/Nov_01/estrogen.cfm
This breakdown occurs primarily in the liver, and the excreted metabolites flow out in the bile or urine. Estradiol and estrone undergo this breakdown through a process called hydroxylation, an enzymatic activity in which the parent estrogen is transformed by the addition of a hydroxyl (OH) group at specific positions on estrogen’s molecular ring.
Estrogen molecules are composed of carbon ring structures that are named numerically. Estradiol has 17 carbon atoms and can be hydroxylated at particular points on that ring. Considerable research has shown that major metabolites of estradiol and estrone are those hydroxylated at either the C-2 or the C-16 positions. Hydroxylated metabolites at the C-4 position also are present, but in lesser amounts. We might think of this process as parent estrogens (estradiol and estrone) begetting daughter estrogens (C-2, C-4, and C-16 hydroxyestrones and hydroxyestradiols). The problem is, some of these are the proverbial good daughters and some are bad daughters. I’ll describe how the “bad” daughters can cause significant trouble.
What makes an estrogen good or bad? That has to do with the biological activity, or potency, of that estrogen. Estrogens are important in a host of cellular activities that affect growth and differentiation in various target cells. This is normal and beneficial, but too much estrogenic stimulation can have a negative effect. Therefore, properly metabolizing and excreting estrogens is crucial. This is how the daughter compounds differ substantially. If these estrogens are metabolized into the 2-hydroxylated estrone and estradiol, they lose much of their cell proliferative and estrogenic activity and are termed “good” estrogen metabolites. Studies show that when 2-hydroxylation increases, the body resists cancer, and that when 2-hydroxylation decreases, cancer risk increases.
I mean that’s from menopausal women but it applies to us as well (E2).
Fiber will help with Insulin, which was said earlier is extremely powerful.
Here is some more to help: Google is our friend
EDIT: hard to read here (gaianaturopathic.com)
Optimizing Estrogen Metabolism
- Minimize exogenous estrogens â?? meats, dairy, use of plastics, etcâ?¦ (Use organic where possible).
- Regulate bowel activity â?? maintain optimal elimination via making time to eliminate regularly, ensuring adequate
exercise and increasing fiber content in diet. (see below).
- Liver support:
ï?· Increase foods to support healthy liver i.e. lemon water; beets; carrots etcâ?¦
- Maintain good weight control:
ï?§ Increased fatty tissue increases estrogen synthesis
ï?§ Maintaining good weight control has an effect on balancing androgenic hormones
ï?§ Eat foods that have low glycemic index
- Decrease pesticide/herbicide exposure â?? organochlorides bind to estrogen receptors and have estrogen-like effect
(organic lawn and garden care and organic foods recommended).
- Do not microwave or store food in plastics. Plastics have been shown to mimic estrogen in the body. (Yes, those
Nalgene bottles too! â?? Bisphenol A, Pthalates
- Eat only unprocessed yogurts and chesses (preferably organic choices). No commercial milk and milk products â??
milk is very high in estrogen b/c dairy cattle are continuously pregnant.
- Water â?? drink only good quality water. Best source is reverse osmosis and to support with extra minerals. But drink
at least filtered or spring water. Drink at least 8 â?? 10 glasses each day.
- Increase complex carbohydrates in the form of whole grains (i.e. buckwheat, kasha, brown rice, millet, quinoa,
etc.), starchy vegetables (no fluffy white potatoes), legumes (they decrease glycemic index). Increased glucose
means increased insulin, which in turn decreases sHBG (sHBG normally binds to free estradiol) resulting in an
increase of free estrogen in the blood.
- Eliminate simple carbohydrates. This means no breads, cakes, cookies, muffins, sugar etc. Anything made with
processed flours must be eliminated.
- Decrease saturated fats and Increase omega-3-fatty acids.:
Fish oil (from a good source â?? Nutrasea, Nordic Naturals). Omega-3 FAs enhance 2-Hydroxyestrone and shunt
pathway away from 16-�±-Hydroxyestrone (more carcinogenic than original estrogen that is being broken down).
- Increase fiber in diet. Fiber binds unconjugated estrogens in gut. Fiber also increases bowel function decreasing
the likelihood of reabsorption of estrogen products from gut due to stagnation of fecal matter.
- Probiotics:
a. Decrease insulin
b. Decreases abnormal bacteria and balances gut microflora
c. Decreases transit time of waste matter
d. Increases bowel function
- Flaxseed meal â?? highest lignan content (lignans decrease aromatase activity and increases sHBG (converts
androstenodione to estrone). Eat 3 TBSP ground flax per day (buy a coffee grinder and grind it fresh daily). Make
it part of your morning ritual.
- Think twice about drugs/medications â?? Cimetidine, marijuana, birth control pills, synthetic estrogen (Premarin),
[quote]schanz_05 wrote:
Darkane wrote:
Interesting.
How’s your Zinc Intake? Also some xenoestrogens might be coming into play. Get rid of glade plug in’s and stuff in the house.
Do you drink out of plastic bottles? What about hot liquid out of plastic?
Try Stainless steel bottles, or glass.
Secondly cruciferous vegetables should be a priority. Broccoli, cauliflower, Brussels sprouts, collared greens, cabbage, cucumbers, bok choy, brocoflower, arugula etc.
Consume as much of these as you can. I do 30oz/day minimum. (about 2 pounds)
I’ve also read some stuff on estrogens and the liver metabolizing them. So a milk thistle supplement with some dandelion might be the ticket.
Make sure fiber is high enough, this can be as much as 50g/day for some. I’m personally at 50g/day when low carb… That’s what it takes for me.
Give er shit man
Thanks for your reply.
A few things:
I was taking ZMA on a regular basis and stopped for some reason. I will get back on that stuff again. I know it helps keep testosterone in check, which with me, my testosterone was in the normal range. So not sure if it will help but I will give it a try.
Im not big on scents and stuff like the glade plug ins you mentioned. I’ve thought about whether xenoestrogens have been sneaking in somewhere and cannot come with anything really. I don’t routinely drink water out of plastic water bottles.
I eat spinach every day pretty much but not a whole lot else for green veggies. Could you explain what the significance of eating fibrous green vegetables and getting enough fiber has to do with keeping estrogen levels in check?
Thanks again for your reply.
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