Just a quick question, for anyone who has any idea. How toxic to the liver would an average steroid dose be, compared to a standard drink of alcohol? Would a daily dose of 17-alkylated muscle juice be equivalent to drinking a whole bottle of hard spirits in one day, or equivalent to just a six pack??
People can drink heavily for years before the liver gives way, so I don’t see how a cycle or two is going to kill one’s liver unless steroids are greatly more liver toxic than alcohol. Somehow, I don’t think they are that much more toxic than alcohol…
No ideas yet? Alright, let’s use methandienone (DBol) as the standard benchmark of comparison, since it is the prototype from which all other steroids were developed.
"More specifically, it’s C-17 alkylated oral steroids that are perhaps detrimental to liver function. But the evidence is equivocal at best. A 1990 computer-assisted study of all existing medical literature found but three cases of steroid-associated liver tumors. Of those three cases, one subject had been taking outrageously large doses of C-17 oral anabolics without cessation for five years, and a second case was more indicative of classic liver malignancy. "
[quote]bushidobadboy wrote:
Yeah, nobody REALLY knows the answer to this as there just hasn’t been enough clinical research on humans. Like anything else though, people respond differently, so the only SURE way to ‘beat the system’ involves getting regular blood panels done. Having said that, minimise use of the really toxic ones (drol, dbol, winny, halo) and practise sensible use of the others, no longer than 8 weeks, with an equal time off, and you ‘should’ be OK. [/quote]
I think the real danger of prolonged use of these 17-AA drugs is changes in blood lipid profiles.
[quote]bushidobadboy wrote:
Prisoner#22 wrote:
bushidobadboy wrote:
Yeah, nobody REALLY knows the answer to this as there just hasn’t been enough clinical research on humans. Like anything else though, people respond differently, so the only SURE way to ‘beat the system’ involves getting regular blood panels done. Having said that, minimise use of the really toxic ones (drol, dbol, winny, halo) and practise sensible use of the others, no longer than 8 weeks, with an equal time off, and you ‘should’ be OK.
I think the real danger of prolonged use of these 17-AA drugs is changes in blood lipid profiles.
I agree, and the fact that 90% of the time these compounds will be coupled with test that requires use of an AI (ideally), just compounds the issue, especially letro which stamps all over E and hence lipid profiles. P22, what do you think about running a low dose of nolva through out an oral cycle, as nolva s estrogen mimicking effect in the liver can possibly offset some of the damage to lipid profiles…?[/quote]
The trick is using just enough AI to keep estrogen levels in normal physiological range. The doses administered of letrozole to cancer patients are unneccessary for use ancillary use in a steroid cycle.
For example of femara I usually use between 0.625 mg ed or eod. The less the better.
Of course blood work would be best method of confirming the approach.
from everything i have read the whole liver thing is blown out of proportion. but if your drinking booze and taking tylenol and eating hfcs there is a possiblitly of messing it up down the road. but most of the people that use orals normally dont do any of these things and are healthy in every other aspect of their lives so i dont think its a big deal.