Yeah man. Wasn’t sure your history.
@roscoe88 that’s not entirely accurate. It CAN help with erections but it can also destroy libido in some or raise it in others.
Try the building blocks first. Give your body a chance.
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Will do.
@physioLojik what do you think of 5 htp?
@charlie12 I think it’s great 
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My wife takes this in the am. Helps with stress during day.
My reading indicates 5htp crosses blood brain barrier better than l tryptophan.
I wonder if wife should take 1 in am and 1 at night.
BTW never knew about gylcine. Am saving this info. Your great. If I would have been in this forum and knew you I would have done differently then the Xanax for a week.
@physioLojik.
It’s a timed release.
I’m still researching this serotonin subject and all of its effects on various systems. Quite the little rabbit hole. I saw physios comment earlier about no sweat and I’m currently diving into that.
I wasn’t much help brother but I’m glad to offer anything I can!
Good luck with it man!
Damn! Thats Rich Piano type size (I’m aware of the grammatical error, I find it funny to spell his last name like that may he RIP)
OLLLLLLLLLLLDDDDDDDDDD (just kidding)
Actually I think you meant yay or yeet, not lame.
300mg is a nice cycle, never used that much b4 but literature backs it up as sufficient to gain significant amounts of muscle mass
Depends, for the recreational intermediate to advanced gym rat I totes agree. For a competitive bodybuilder and/or dude on the verge of an IFBB pro card 500-1g if gear or even more if IFBB pro seems reasonable. Granted I wouldn’t ever venture into that territory.
I have so much built up test from my script that I haven’t used. I’m prescribed 150mg per week but have using so much less. I think test is good for a long long time.
I may try an actual cycle of 300mg a week at some point. I’ve never done a steroid cycle in the past (just my trt).
@roscoe88 have you tried varying your dosage slightly from week to week. This has been recommended by @physioLojik and others on here. I didn’t have the increase in libido that I expected from trt either until I started varying my dosage by 20mgs or so a week. It has worked well for me.
I can tell you that I suffer from depression. It gets really really bad. It didn’t occure to me until about two days ago that I haven’t had an episode since starting hcg. So that’s been about three months. Not even a little episode. I haven’t had my estrogen levels checked but I am not on ai’s.
How does that work and why is it helpful? What’s the body response that’s beneficial.
There is definitely some validity to your theory from a pharmacokinetic standpoint. The problem is that from a pharmacodynamic standpoint ie what the drug does to the body, we simply don’t really know. This is the point I was making, as there are no studies I have seen which address what effect smaller more frequent injections have on estradiol levels. The one study I saw with daily T injections was done by a private group who also gave twice weekly HCG and DAILY Arimidex, so you cannot draw any conclusion as to E 2.
The other point that really needs to be emphasized is that the same drugs at the same dosage can have very different effects in each individual. That’s the essence to me of pharmacodynamics. My first TRT cycle was 100 mg of cypionate once a week with 0.5 mg of Arimidex along with the injection. My TT hit >1500 on day 3 and this was four weeks after I started. Someone else may see a level of less than 600. Age, SHBG, and other factors are probably involved.
I think physio’s point of optimizing the body one hormone at a time is still the best rule. For now I am going to continue at 40 mg subcu q 3.5 days, and hold everything else for at least 4 weeks when I will see my current urologist. He’s letting me run the show just like my last doc.
I appreciate everyone’s input and feedback.
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So what I think I am understanding you to say is that theoretically I am correct in how the drug will be concentrated in the body, but how the body reacts to that concentration will be completely individual. Is this about the jest of it?
If so, I could say that the 3xW protocol is still probably more effective in making that determination, because of the slower ramp time. If the concentration ramp is wildly fluctuating, and a particular individual has a rapid metabolism and aromatases faster, is it not fair to say that this guy could end up suffering worse because he would have to wait a longer period due to the fact that his (lets call it aromatase threshold for lack of a better term) was over shot so badly on the higher single dose?
It seems that the more frequent protocol would be more effective at not having those threshold overshoots and thus in turn help to not have wild spikes in E2.
I guess if someone doesn’t aromatase much, or has a much slower test metabolism then it wouldn’t matter either way, but that further outlines the argument for more frequent protocols doesn’t it?
If a weekly protocol can have a drastically different effect in two different people (one of them having no issues and the other having tremendous spikes in E2), and a more frequent protocol can minimize the overshoot of E2 even if one of the individuals has a faster aromatase rate, then wouldn’t it be less stressful to someone starting TRT to begin with frequent injections, and then judge over 6-8 weeks how his E2 levels are reacting, rather than give him one big injection that could possibly surpass his “aromatase threshold”?
Thank you for responding by the way. I learn a ton by engaging in these conversations!!
Edit to add…
This…
I 100% absolutely agree with and all of my above points / theories are based on a protocol that follows this premise exclusively.
Mmm the docs that talk about this say this is proven through their experience practicing these protocols. They have someone go on the protocol, run bloods, get feedback, and after dozens or hundreds of clients they realize it to be working.
It is definitely obvious every body behaves diffeeent on medicine and chemicals. I know people who cannot take pain killers because it doesn’t work on them. Others smoke some thc and nothing.
In regards to daily injections and its effect on e2… I have been seeing and reading the arguments for and against this. Here is what I think on this topic. People are saying openly that daily injections with Cypionate/Enanthate more closely mimic the bodies natural rhythm and that’s why they believe it to be superior to larger less frequent injections. In my mind this cant be correct. We know that our bodies before trt and functioning in a healthy manner feed testosterone in pulses. These pulses of testosterone occur at night early in the morning. Because of this we know there is a peak plasma level of testosterone in the morning that begins to decrease immediately and does so throughout the course of the day. This is an issue for some of us because we had testosterone testing done in the afternoon and our insurance companies wont recognize these test for this reason. Once we go to sleep this process begins again. This tells me that our bodies testosterone (which has no ester) has a very short half life. I’ve seen claims that our natural testosterone can drop as much as 30% from morning to afternoon. Based on this knowledge how can we compare injecting a testosterone with a 7 to 8 day half life to our natural production? I have seen the charts and granted the peaks and valleys of testosterone are obviously smaller so that would lead us to believe if anything that the estrogen would behave in a similar fashion. Atleast stay at a more consistent level on a weekly basis. Why is that so important? If our natural levels are fluctuating so much on a daily basis then why would we so unnaturally try and keep our levels so stable on a daily basis? Fluctuations in our hormones is natural and healthy. Test and e2 go up and down daily. Serotonin builds up throughout the day and synthesizes into melatonin to help you sleep. Not to mention your sticking yourself with needles on a daily basis and your using 7 needles a week. I dont know the answer here I just think that anyone who is attempting this protocol use the shortest ester possible. It’s the only thing that makes sense to me. Good luck to you all.
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All one need do is try aqueous testosterone, aka suspension. It’s water based, no ester. In you fast, gone in 4-5 hours. After that injection, you’re looking for a gym or a woman…
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Overdrive is about to drop something big. I’ve been sitting here waiting and checking back for his post for a while and he has been typing a while lol
I agree with this to some degree, but keep in mind that the release of testosterone in our body naturally, when it’s functioning normally, is not near as much concentration at once as the exogenous Test that we inject.
I do whole heartedly agree that ED injections are overkill. It just doesn’t divide evenly with the half life of test Cyp so there is no point where there is a drop in concentration. With at least a small spacing, it gives the opportunity for small fluctuation of up and down. With ED, it’s a steady climb up with no drop whatsoever, or at least a very insignificant drop.