I want to know the best way to minimize a reduction of ephedrine’s effects over time. I’m aware of the practice of using benadryl to upregulate the beta receptors overtime for drugs that downgrade them (clen, albut’l, ephedrine etc); I’m under the impression that ephedrine aggravates all three types of beta receptors but doesn’t aggravate any of them necessarily heavily.
I’m trying to figure out the best way to cycle this drug if I’m looking only for it’s ergogenic aid in the weight room…
I was thinking 3 weeks on, 25mg just the days I train five or six days a week, then the 4th week a back-off week with benadryl therapy and no ephedrine; And I could repeat this continuously. Does this sound good or would I require more time off of ephedrine to maintain it’s maximum benefits at these doses? I’m thinking I probably wouldn’t at these doses, with benadryl, and with one week off for every three weeks on.
Any body else got any opinions or material I can read about ephedrine cycling? I’ve searched the internet but couldn’t find what I was looking for.
Don’t know if this will help…it’s from Author Rea…
Unlike Clenbuterol, Ephedrine and Norephedrine did not cause an excessive adaptive response and therefore continued to effect thermalgenic activity for months.
Both induce the release of “Noradrenaline”, which in turn stimulates all three beta receptor sub types, and both can stimulate the same receptor-sites directly to some degree. Ephedrine products induce the thermalgenic effect by stimulation of all 3 receptor sub types, but 35-40 % of their stimulatory effects are upon type 3 beta receptors.
This is significant because the response governing activity down-regulation of beta 2 receptors is not possible with beta 3 receptors. So ephedrine products have potential long term effectiveness. Simple? Beta-3 receptor stimulation increases the break down of fats. This also results in an increase in uncoupling protein levels. It should be noted that Ephedrine products increase the conversion of T-4 to T-3 by the liver. (Yup!!)