Look at studies regarding cognitive function and daily smokers over prolonged periods of time (heavy daily use mind you)… some studies indicate the deficits only last between 72hr-1 month post abstinence, others indicate perhaps deficits are permenant, esp when use is initiated prior to the age of 17… we don’t have enough general research pertaining to marijuana to come to an adequate conclusion due to restrictions imposed via it being (unfairly) schedule I (or equivalent in most countries)… Occasional use for most appears relatively harmless, nothing compared to even mild/moderate rates of drinking in terms of neurological/overall damage induced.
NDMA receptor blockcade mediated neurotoxicity is a huge concern with ketamine use/abuse. ketamine induced neurotoxicity is dose/situation dependent, there is literature to state in an acute setting (for certain circumstances) perhaps ketamine may elicit a neurodegenerative via BDNF activation. Prolonged abuse of ketamine is neurotoxic. The effect of ketamine on neurology pertaining to occasional users/anaesthetic use (for those frequently put under) remains relatively unknown.
Addict? I haven’t partied since December, and my exposure to recreational drugs doesn’t pertain to frequent use… aside from cannabis it’s merely a number of select occasions. The drug I’ve personally had problem with is alcohol, wherein I would drink not to have fun/for recreation, but to numb pain/anxiety. Neither problematic episode regarding booze lasted very long as I managed to realise it was problematic behavior and thus quit drinking abruptly. Haven’t been drunk since December. It should be noted this wasn’t an addiction either, it was substance abuse as a crutch… There was no semblance of psychical addiction, otherwise quitting cold turkey would’ve induced serious withdrawal symptoms/potentially killed me. Admittedly stopping abruptly the second time wasn’t exactly the easiest thing I’ve ever done, it wasn’t comparable to the most difficult thing I’ve ever had to do either.
Alright, if you’ve got an 85% occlusion in multiple arteries, try eating a healthier diet to reverse the buildup… tell me how that goes. The problem is you fundamentally don’t understand the process of plaque build up, theoretically one may be able to reduce the amount of plaque they have… but it’d stem from MAJOR lifestyle changes over a very long period of time… continually using AAS during this time won’t allow for this.
You’re the one justifying certain behaviors by refusing to believe scientific literature on the basis of anecdote, using an “but I’m fine, I haven’t died yet thus it’s not dangerous” type logic. DNP lowers you’re WBC count, sometimes to the point of inducing life threatening agranulocytosis. This is about the worst thing you could possibly do during a pandemic scenario revolving around a viral illness.
You’re case report refers to an elderly male with a host of health ailments (and potential neurodegeneration to begin with), giving him (or anyone) opiates for that matters effects executive function… Just as taking a few hits off a joint (non medicinal and without a tolerance) five minutes before a test would deleteriously impact test performance. The impact doesn’t appear to be permenant following abstinence. Opiates acutely do fuck with cognition, they’re highly sedating… And they give the user a “high” (can’t say I’ve ever understood what it’s all about), but some people love them. Aside from fentanyl and the prospect of addiction (so long as you know what you’re getting) opiates aren’t actually that dangerous (acutely). If you take 20mg oxycodone (say you’re a kid and you stole you’re grandma’s prescription… Apparently people do this… this is an incredibly stupid thing to do) it’s a hell of a lot safer than binge drinking to reach an equatable state of intoxication. Doesn’t pertain significance as not many people who use oxycodone, heroin etc use it “just once”, it happens, but it’s rare.
So around 1.5g/wk, not extremely heavy, not mild either. Given the strength of test/primo mg/mg in comparison to test alone I’d say this is fairly reasonable. No problem there
Our opinions align here, aside from the cooperation aspect… I get agitated by the amount of people who buy into this “deep state cooperate conspiracy theory” within the medical industry. Yes, these large companies are focused on making a profit, but generally (aside from alcohol/tobacco) these companies aren’t interested in hurting their consumer base. The only time I harbour mistrust/skepticism related to the government, the establishment as a whole. Many a times I believe politicians and/cooperations have a vested interest at heart, same can be said about large cooperations. The criminalising of marijuana to begin with was based on hatred towards immigrants, people of different race etc… Not because it was a legitimate detriment to the populace. If anything, criminalising the substance made it far more popular than it otherwise would’ve been.
My problem here is when you refer to “cooperations” you’re talking about the medical community, at least I think you are. It is within the medical communities best interest to keep the populace healthy in order to lessen burden on an already taxed healthcare system. We have enough problems stemming from shitty lifestyles, disease (autoimmune for instance), congenital etc for medical professionals to earn through visitations.
Actually 1-2x yearly my chronic pain will flare up briefly. During which time I’m happy to take the pain medication prescribed in my name at the dosage indicated.
Agreed, if you can actually afford it without any long term ramifications.
I don’t like hypothetical scenarios here as these are highly implausible. But imagine I decide to act like a massive idiot (actually I know someone who this DID happen to) and decide to take some fentanyl on a night out without any prior experience/tolerance (perhaps I’m drunk, perhaps I’m taking laced xanax/oxycodone… whatever). The second serious respiratory depression sets in I’m given narcan. The amount of damage induced will pale in comparison to cycling over many years/taking DNP. Keep in mind you’ve said ALMOST overdosing. A benzodiazepine overdose probably won’t kill you either so long as it isn’t combined with other substances, nor is it likely to seriously harm/induce structure alterations to you’re internal organs.
Almost overdosing on alcohol once (so I throw up) but I’m not paralytic/requiring paramedics probably won’t kill me/induce significant harm if it was ONCE and only once, granted there are case reports of acute myocardial infarction etc) stemming from otherwise healthy, yet highly inebriated young people. Furthermore I probably won’t acquire cardiomyopathy (aside from the VERY rare instance of binge ethanol induced takotsubo cardiomyopathy… reversible), renal/liver failure (you said, nearly overdose… Not overdose overdose) from getting very drunk once… It is possible, though unlikely. I’d be more likely to die from behaving like an idiot/getting hit by a car from wondering into the street, getting into a fight etc.
How, by telling you flirting with potentially near lethal dosages of drugs is a bad idea? Or by telling you there are long term implications regarding you’re decisions? You’re the one who has decided to completely ignore current science/literature on the basis of “corperatinos have vested interests”.
Which corporations? The majority of scientific research is funded via government grants, you make a request… if they approve, you’ve got the funding (very simple way off putting it). Typically the government won’t be heavily involved within the study and many studies pertaining to the health status/implications of AAS use outwardly try account for bias. The case reports of sudden death, cardiomyopathy, renal/hepatic failure stemming from AAS use (hepatic failure being sole to C17AA compounds) aren’t “bias” or “corporate bullshit”… neither are the MANY case reports that exist regarding DNP fatalities.
You can’t get on the treadmill for more than five minutes… does this scream “healthy, no adverse effects” to you?
What’s you’re current resting heart rate on Clen, DNP, tren, EQ and test… if it’s over 90, does that scream healthy to you?
How so? What BS? Which part of my messages are clouded in BS, give me exact specifics pertaining to the exact “corporations” at fault here. If you wished for me too believe perhaps in part due to government propaganda during the 80s/90s anabolic steroids were unnecessarily scheduled as a controlled substance (because cheating in sport, can’t have non American’s winning). That they shouldn’t be stigmatised because they aren’t as dangerous as they’re made out to be… that there’s a TON of public ignorance today regarding AAS etc I’d believe you. As a matter of fact the FDA, congress etc opposed the ban, stipulating they weren’t dangerous drugs of addiction (at least in an acute setting).
Societally we unjustly are very tough on AAS. Unlike marijuana, recreational drugs etc I don’t believe public opinion regarding anabolic androgenic steroids will ever shift.

