Some initial findings indicate that it depends on the concentration of the virus one is exposed to - supposedly that’s why a lot of medical staff, exposed to higher concentration of the virus, perished while people who picked it up from secondary sources (surfaces etc.) have midler symptoms.
However this is still in the realm of speculation.
That is interesting. Do other viruses follow that finding?
I guess I always thought that a small amount turned into a large amount inside the body?
It seems to make an intuitive kind of sense.
Mild absorption of say a few hundred million individual microorganisms, not bad.
Bombarded by billions per day, day after day, while being physicaly and psychologically stressed = really, really bad.
It would match similar viruses. SARS and MERS etc.
Precisely, and then going down with a bad case is really bad. They aren’t easily replaced and it it’ll end up with a very important resource being out of action or, God forbid, on death’s door.
This is true, yes. To some degree the “large amount” also depends on the extent of immunogenicity the virus displays–how fast and how much of an immune response is generated by the virus. This varies by virus through myriad methods.
Think of it like a building fire, with the fictional situation set such that the speed of the fire department response is dictated by how many people pull the alarm. The more people and the sooner they pull the alarms, the faster the firefighters get there. That’s high immunogenicity. A slow, lazy pull of the alarm means the fire has more time to spread and intensify before the truck gets there.
However broadly speaking you’re very much right.
In general for respiratory illnesses. You’re talking about “viral load”, or # viruses per some unit of volume (say, in a mL of blood, or whatever). The specific kind of viral load we are talking about for infection is called viral “shedding” which is the amount of viral particles a person gives off in sneezes, coughs, etc.–their infectiousness.
It gets tricky though, because in general the frequency and duration that someone is exposed to the virus are known risk factors, which is obviously true of medical staff. This is true for the recent Ebola outbreaks as well as numerous other infectious diseases.
Factors that affect the likelihood of a severe case are:
Immunogenicity–how much of a virus presence is needed to cause an immune response
Frequency of exposure
Duration of exposure
Viral load (viral shedding) in an exposure
There are numerous others naturally.
EDITED–to clarify that viral shedding is the term we need to look at when talking about viral loads
Maybe?
I don’t actually know. Like I said, to me it seems intuitive, like a dose dependent response. And the stressor are guaranteed to exacerbate.
BUT I don’t actually know any of this, and wouldn’t want it to be mistaken for actual knowledge.
Nor I, but very smart people I know, Aragorn included, have mentioned it as an issue. Like you, I can grasp that it seems like it should be an issue.
My virologist friends have all mentioned it, so I take it to be a good bet, even if it’s not confirmed yet.
I thought “viral load” was pretty much agreed on.
Stress and being overworked weaken the immune system. And it’s not like no doctors or nurses might have underlying conditions.
No surprise here:
Trump signed the stimulus Bill.
“I want to thank Democrats and Republicans for coming together and putting America first,” Mr. Trump said at the ceremony to sign the bill in the Oval Office".
No Democrats were present for the signing, and an aide to House Speaker Nancy Pelosi confirmed she wasn’t invited.
I wouldn’t know, I suck at biology. And frenzied reading of Nature articles during lockdown cannot make up for years of ignorance.
You know how we tell kids “Don’t make faces or it will stay that way.”.
Well that actually happened last time Nancy got shit faced.
Anyhoo, do you think there is any validity to the accusation that she held up that bill to continue stuffing it with pork.
If so, how much? Like half? Maybe half of the accusations are true?
Cuz if that were true, even half, I wouldn’t invite her either.
So confusing… From everything I see on TV it kills the old and people with 2-3 conditions… Not exactly sure all the conditions but seems to be diabetes, heart disease, and respitory stuff. Possibly smokers or people that vape… Totally doesnt make sense thou… Every other day reports of healthy people dying. Young people too… I heard a texas a&m rb died of it… But at same time seats like non of the guys in NBA that caught it head such to say. Sears like they just brushed it off… I would think good cardio gives you a fighting chance but who knows.
Hell of a way to find out there was a previously unknown/undetected condition.
Searched for that, but this was all I found:
Rhode Island police began stopping cars with New York plates Friday. On Saturday, the National Guard will help them conduct house-to-house searches to find people who traveled from New York and demand 14 days of self-quarantine.
“Right now we have a pinpointed risk,” Governor Gina Raimondo said. “That risk is called New York City.”
New York is the epicenter of the coronavirus outbreak in the U.S., on Friday reporting a total of 44,000 cases.
If the rate of growth in coronavirus cases continues, the New York City metropolitan area will suffer a more severe outbreak than those experienced in Wuhan, China, or the Lombardy region of Italy.
There is no guarantee, of course, that current trends will continue. What has happened to this point can’t be used to predict what will happen next. It is possible that social distancing will soon slow or arrest the growth of cases.
But what can be said is that the New York metro area has had less success in flattening the curve, at this point in its outbreak, than Wuhan or the Lombardy region did at the same point in theirs. And some other American metropolitan areas appear to be on a similar path.
Here are four ways to measure the size of the outbreak across the country’s metro areas.
The fact that you even asked the question, @SkyzykS, emphasizes something that I’ve said often on this site: 1) the DEMS need a new PR firm 2) they need a dedicated, unwavering, “We are 100% always right/They are 100% always wrong” “news” organization dedicated to their cause like “FOX” and 3) the benefit of the Russian mis-information machine.
There are ~ 53 GOP Senators and ~ 200 GOP Members of the House. So what did they do…sit in their chambers; pleading and crying…" Oh, please, PLEASE, Miss Pelosi! We be good! Could 'ya please just give us a TINY bit of that Pork…we be SO appreciative if you do!"
Bullshit. All sides got some of what they wanted while conceding things to the other side. That’s how it works. Change the Law…or more importantly…be prepared to give back any little piece of pork that may benefit you and/or your district or State.
Right.
So no. The bill was held up because 1) it is a HUGE piece of legislation 2) wording in Bills is all important, which has Congressional Aides and Lawyers working around the clock 3) the lack of oversight, controls and contractual agreements just weren’t there. Protect your workers, folks…not just buy back a lot of stock, fire people and give executives huge bonuses and 4) It was demanded that these large corporations be put under contractual agreements. ( Much like the GM bailout during the Obama Administration).
One last thing that I alluded to in another thread…you can hate these experienced DEMS like Pelosi and Shumer all you want (not the AOC’s and Talib’s of the Party)…there is one thing these Inglorious Bastards know how to do…that’s to put together huge Legislation like this; negotiate it; twist some arms/give some-take some…and get it passed.
They weren’t invited to the signing because Trump is a narcissistic, vindictive, small little man.
Why? Did they fire MSNBC and CNN?