529 pmol/L * 1 nmol / 1000 pmol * 288.431 ng / nmol * 1 L / 10 dL = 15.3 ng/dL = 153 pg/mL to 3 sig figs as per measurement
Note: 1 ng/dL = 10 pg/mL
What you typically see is ng/dl if you are getting an accurate equilibrium dialysis free T test. Ref ranges vary from 5 up to 28 ng/dl depending on lab. Your number above is 15.3 ng/dl for comparison.
Also there’s a misleading direct RIA fT test that is typically reported in pg/ml.
You’d have to post an old test or do some more hw to determine what you typically get back from lab.
Who is they?
Your TT above is 597 ng/dl. You can use online calculator to plug in SHBG and TT and confirm fT number i converted for you.
Various Forums and YouTube TRT guys state many people don’t feel “optimized” until their Free T hits 25 and better yet, 30+.
Holy crap, so despite 15.3 being HIGH according to Canadian labs, I’m at half of what these guys are saying, Was it another unit they are talking about? LOL
I’d have to see the particular assay you used to measure TT. The upper ref range 25.7 nmol/l (741 ng/dl) tells me it doesn’t have 1:1 correspondence with say Labcorp LC/MS-MS assay which has a higher ref range. So I’d put 28 ng/dl as true top of fT ref range. It’s all very arcane.
But to your point, I have a hard time understanding a guy on TRT running a fT of 50 ng/dl long term. But that’s just me.
This optimization lingo is all bullshit. What are we optimizing? What’s the time horizon? Blah blah. See my TRT thread if you want more info and entertainment.
The issue as framed above is that the fT above is calculated on SHBG and TT. Since the TT above wasnt LCMS we dont know the absolute accuracy of the calculated fT above. Relative vs absolute error.
I think a lot of times people are freaking on the upper ref range of their TT assay and think there is a major conspiracy. Sure TT levels are dropping some [obesity, etc] but the other reason is labs are using an immunoassay for TT thats highly correlated with LCMS result but the parity plot is not slope of 1 and intercept of 0. So they see the upper ref range at 600 or 700 ng/dl and are like WTF?
Then you take this result and calculate fT which propagates the absolute error on the TT result.