Changed Dose Two Weeks Ago, Feeling Worse

Pharma TRT
1

Hey all,

I was taking 70mg test cy 2x a week along with 1mg week of arimidex split over 4 doses. This put me at about 1200 total t and 11 e2 (I’m aware you’ll think that was too low).

Anyway because of accelerating hair loss and concerns about ai I decided to lower my dose to 120mg total and no ai. I did this about 2 weeks ago. I recall when I briefly ran at 130mg my test was much lower (around 800).

Anyway it’s been 2 weeks and for the last few days have felt listless and gloomy. I have depression issues but this feels qualitatively different. I doubt this is all in my head because it just dawned on me today to wonder if it was the reduced dose. So my questions are:

  1. Might I feel a difference in just two weeks if I’d reduced my t dose?
  2. If so, might this be a short term thing? Might (and I don’t really know what I’m talking about here), my testosterone receptors have down regulated and now need to upregulate to adjust to new dose?
    I realize that a lower dose may just not work for me, I’m just wondering at what point I should decide it isn’t working.

Thanks!

2

Probably still too early to tell. I’d give it another few weeks before getting blood work and exploring the effects of changing your dose.

2 Likes
3

Like iron_yuppie said its still too early…4 to 6 weeks and gauge from there. Do you take any other supplements? Do you have recent blood work results you can put up for us to see?

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4

It takes a minimum of 6 weeks to your body to adapt to dosing changes. You cannot know if lowering the dosage will not work unless you give it enough time, you are just looking for a way out of how you feel, if you don’t allow your body time to get used to the new dosage, I don’t imagine you’ll ever feel good on TRT if you don’t give it enough time.

Everyone feels a little off after a dosage change.

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5

Feeling a bit off as well but who gives a fuck it’s only been 2 weeks for me as well. Patience is the name of the game. Everything else clicks good. Excited to see labs in 6-8 weeks time.

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6

Give it time mate, as everyone is suggesting. Then manage from there.

7

11 for E2 is too low. Back off the anastrozole or stop it completely

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8

Did you even read the post? He already stated he stopped it.

Op need to give at least 4 more weeks for things to settle down. Then gauge symptoms and labs.

9

Thank you for clarifying all knowing Charlie.

And FYI no I usually don’t have time to read the entire thread.

10

Np. I do the same thing. But am just a regular joe